Nanocapsules applied in pharmaceutical delivery systems.Nanocapsules used in Drug Delivery System

Volume: 10 | Issue: 02 | Year 2024 | Subscription
International journal of Nanobiotechnology
Received Date: 08/01/2024
Acceptance Date: 09/14/2024
Published On: 2024-10-11
First Page:
Last Page:

Journal Menu

By: Vivek L. Ahire, Vaibhavi [email protected] D. Patil, Vaibhav G Badgujar, and Dinesh P. Badhane

(1-4)Student, Department of Pharmacognosy, Ahinsa Institute of Pharmacy, Dondaicha, Maharashtra, India

Abstract

Nanocapsules, which are minute vesicles composed of a parent material shielded by a polymer casing to encase the drug in the nucleus while regulating the drug’s dispensation and targeting capacity, represent a ground-breaking advancement in the realm of pharmaceuticals. The purpose behind the creation of nanocapsules is to enhance their efficiency and functionality by leveraging various methodologies like polymerization, solvent diffusion, dialysis, and supercritical fluid technology. These nanocapsules introduce a groundbreaking strategy for drug delivery by furnishing a method for controlled release, enhancing the drug’s bioavailability, and facilitating precise delivery to specific anatomical locations in the body. Through rigorous exploration of different nanocapsule variations, their immense potential for effectively delivering a wide array of medications, particularly antibiotics, peptides, and proteins, has been unveiled, showcasing their exceptional adaptability and utility in medical treatment. By managing the pace of drug release, nanocapsules can significantly prolong the therapeutic impact of medications while diminishing undesirable side effects, thereby enhancing patient well-being. Moreover, nanocapsules perform a crucial function in amplifying the solvency and permeability of poorly-soluble medications, which in turn fosters optimal absorption and dispersion within the body. Notably, in clinical scenarios, the demonstrated efficacy of nanocapsules in treating an extensive range of illnesses, encompassing malignancies, cardiovascular ailments, and infectious maladies, underscores their potential as a transformative technology in the realm of drug delivery. The promising versatility of nanocapsules in addressing a diverse spectrum of medical conditions signifies their importance as a multifaceted tool in the therapeutic landscape.

Keywords: Nanocapsule, encapsulated, polymeric membrane, salting out

Loading

Citation:

How to cite this article: Vivek L. Ahire, Vaibhavi [email protected] D. Patil, Vaibhav G Badgujar, and Dinesh P. Badhane, Nanocapsules applied in pharmaceutical delivery systems.Nanocapsules used in Drug Delivery System. International journal of Nanobiotechnology. 2024; 10(02): -p.

How to cite this URL: Vivek L. Ahire, Vaibhavi [email protected] D. Patil, Vaibhav G Badgujar, and Dinesh P. Badhane, Nanocapsules applied in pharmaceutical delivery systems.Nanocapsules used in Drug Delivery System. International journal of Nanobiotechnology. 2024; 10(02): -p. Available from:https://journalspub.com/publication/nanocapsules-used-in-drug-delivery-system/

Refrences:

  1. Ezhilarasi, P. N.; Karthik, P.; Chhanwal, N.; Anandharamakrishnan, C. (2012).“Nanoencapsulation Techniques for Food Bioactive Components: A Review”. Food and Bioprocess 6 (3): 628– 47. Doi:10.1007/s11947-012-0944-0 (https://doi.org/10.1007%2Fs11947- 012-0944-0) .S2CID 98381808(https://api.semantiCscholar.org/CorpusID:98381808)
  2. Nagavarma, B V N; Yadav, Hemant K S; Ayaz, A; Vasudha, L S; Shivakumar, H G(2012). “Different Techniques for Preparation of Polymeric Nanoparticles –A Review” (http://www.ajpcr.com/Vol5SupPl3/1128.pdf) (PDF).  Asian  Journal of Pharmaceutical and Clinical 5(Suppl 3): 16–23
  3. Nagavarma, B V N; Yadav, Hemant K S; Ayaz, A; Vasudha, L S; Shivakumar, H G (2012). “Different techniques for Preparation of Polymeric Nanoparticles – A Review”(PDF). Asian Journal of Pharmaceutical and Clinical 5 (Suppl 3): 16–23.
  4. Mironov V, Kasyanov V, Markwald RR. Nanotechnology in vascular tissue engineering: from nanoscaffolding towards rapid vessel biofabrication. Trends in biotechnology. 2008 Jun 1;26(6):338-44.
  5. Guinebretière S, Briancon S, Lieto J, Mayer C, FessiH.Study of the emulsion- diffusion of solvent: Preparation andcharacterization of Drug Dev Res 2002; 51: 1-16.
  6. Zaman Addressing Solubility through Nano Based Drug Delivery Systems. J NanomedNanotechnol. 7, 2016, 376.
  7. El-Shabouri, H. Positively charged nanoparticles for improving the oral bioavailability of cyclosporin-A.Int. J. Pharm. 2002,249, 101–108. [CrossRef]
  8. Nagarwal, R.C.; Kant, S.; Singh, P.N.; Maiti, P.; Pandit, J.K. Polymeric nanoparticulate system: A potentialapproach for ocular drug J. Control. Release 2009,136, 2–13. [CrossRef] [PubMed]
  9. Sindhwani S et al. Three-Dimensional Optical Mapping of Nanoparticle Distribution in Intact Science Advances. 1, 2016, 10.
  10. Kepley C. Fullerenes in Medicine; Will it ever Occur. J NanomedNanotechnol. 3, 2012,
  11. Kazue M  et        Antimicrobial     Photodynamic     Therapy     with Functionalized Fullerenes:Quantitative Structure-activity Relationships. J NanomedNanotechnol. 2,2011, 109.
  12. Modi, B.D. Anderson Determination of drug release kinetics from nanoparticles: overcoming pitfalls of the dynamic dialysis method Mol. Pharmaceutics, 10 (8) (2013), pp. 3076-3089,
  13. Vauthier and K. Bouchemal, “Methods for the preparation and manufacture of polymeric nanoparticles,” Pharmaceutical Research, vol. 26, no. 5, pp. 1025–1058, 2009. View at: Publisher Site| Google Scholar
  14. Boudad H, Legrand P, Lebas G, Cheron M, Duchene D, Ponchel G. Combined hydroxypropyl-β-cyclodextrin and poly (alkylcyanoacrylate) nanoparticles intended for oral administration of saquinavir. International journal of pharmaceutics. 2001 May 7;218(1-2):113-24.
  15. Demir Genotoxicology of Quantum Dots Used in Medical and Pharmaceutical Sciences. Hereditary Genet. 4, 2015, 151.
  16. Ingale AG et Chaudhari AN. Biogenic Synthesis of Nanoparticles And Potential Applications: An Eco-Friendly Approach. J Nanomed Nanotechol. 4, 2013, 165.
  17. Couvreur P, Barratt G, Fattal E, Legrand P and Vauthier C . 2002 Nanocapsule technology- A Crit Rev Ther Drug Carrier Syst, 19(2), 99-134
  18. Zha, L. & Hu, W. Homogeneous crystal nucleation triggered byspinodal decomposition in polymer solutions. Journal of Physical Chemistry B 111, 11373–11378, doi: 1021/jp068431c (2007)