A Comprehensive Review on Insulin Resistance

By:

Ayesha saddiqa, Luqman Hakeem, Muhammad HannanSaleem, Arooj Aslam, Hussnain Ahmad, Kashif Nawaz, Umer Ali, Hafiza Rabia Shaifq, Nabila Iqbal, and Muhammad Kaleem Ullah

Volume: 10 | Issue: 01 | Year 2024 | Subscription
International Journal of Immunological Nursing
Received Date: 03/08/2024
Acceptance Date: 04/08/2024
Published On: 2024-04-15
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Citation:
Ayesha saddiqa, Luqman Hakeem, Muhammad HannanSaleem, Arooj Aslam, Hussnain Ahmad, Kashif Nawaz, Umer Ali, Hafiza Rabia Shaifq, Nabila Iqbal, and Muhammad Kaleem Ullah A Comprehensive Review on Insulin Resistance International Journal of Immunological Nursing. 2024; 10(01): -p.
Abstract

Abstract

Insulin resistance is a complex condition where cells in the body, such as those in the liver, fat, and muscle, do not respond properly to insulin. Insulin resistance can be temporary or incurable, leading to increased insulin production known as hyperinsulinemia, which may contribute to obesity and eventually progress to type 2 diabetes. This mini review elaborates the historical context of insulin discovery and its therapeutic use. It highlights the importance of insulin and insulin resistance in the context of metabolic diseases and discusses factors contributing to insulin resistance, such as poor diet, obesity, heredity, physical inactivity, and certain medical conditions. Lifestyle changes and pharmacological therapies are suggested for managing insulin resistance. The role of insulin in maintaining blood glucose levels and its resistance in various tissues, leading to compensatory hyperinsulinemia, are also discussed. It emphasizes the significance of understanding risk factors, lifestyle changes, and pharmacological interventions in preventing and treating insulin resistance. Additionally, it touches upon insulin’s effects on glucose metabolism, the insulin resistance syndrome, and the clinical diagnostic entity known as metabolic syndrome. The impact of various factors on insulin secretion and production is also mentioned. Overall, the it provides a comprehensive overview of insulin resistance, its consequences, and approaches to its management.

Keywords: Insulin Resistance, Obesity and Diabetes, Hyperinsulinemia, Metabolic Syndrome,

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Citation:

Ayesha saddiqa, Luqman Hakeem, Muhammad HannanSaleem, Arooj Aslam, Hussnain Ahmad, Kashif Nawaz, Umer Ali, Hafiza Rabia Shaifq, Nabila Iqbal, and Muhammad Kaleem Ullah A Comprehensive Review on Insulin Resistance International Journal of Immunological Nursing. 2024; 10(01): -p.

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