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    Study of the Effect of SLS Loading on the One-Pot Synthesis of Substituted Piperidines

    Abstract: Piperidine derivatives represent a vital class of nitrogen-containing heterocycles with extensive pharmacological and industrial significance. Their synthesis has garnered considerable interest due to their presence in numerous bioactive molecules, including drugs with CNS activity, analgesic properties, and antimicrobial effects. Traditional multi-step synthetic pathways are often time-consuming and resource-intensive. To address this, one-pot multicomponent reactions (MCRs) have emerged as an efficient and eco-friendly alternative, allowing for the rapid construction of complex …

    Published in International Journal of Green Chemistry · Vol. 12, Issue 1, 2026 · pp. 1–9 Read article

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