Potential of Novel Carriers for Effective Management of Acetaminophen Induced Hepatotoxicity

Archana Dhyani; Divya Juyal

International Journal of Applied Nanotechnology

Potential of Novel Carriers for Effective Management of Acetaminophen Induced Hepatotoxicity

Abstract

Liver is a vital organ of the human body. It plays an important role in the human body. Acetaminophen when taken in therapeutic doses, it is used in the treatment of various conditions. Hepatotoxicity is the prime factor responsible for drug withdrawal from the market. There is no doubt that hepatotoxicity requires considerable attention and that every viable measure be taken towards an efficient mechanism for hepatoprotection. The overdose of acetaminophen causes acute liver failure. The hepatotoxicity can be treated by targeting the liver by the various carriers like liposomes, nanoparicles, phytosomes etc. However the hepatoprotective therapies require better targeting, stability and better bioavailability. Such focus areas can be effectively met with the aid of lipid based delivery systems which can prove to be a breakthrough in the field of hepatoprotection. Keywords: Hepatotoxicity, acetaminophen, acute liver failure

Keywords

Full text

The full text of this article is available to subscribers.

On a subscribing campus you are let in by network address, with no login at all.

One-off purchase. Permanent access to this article, no account needed.

A year of online access to every article in International Journal of Applied Nanotechnology. Or choose several journals →

Article details

Potential of Novel Carriers for Effective Management of Acetaminophen Induced Hepatotoxicity

Abstract

Keywords

Read more of it

Publish your article

Abstract

Keywords

Related articles

Investigation of 2, 4-D Hepatotoxicity and Lepidium sativum Antitoxicity on Rat Tissue using FT-IR Spectroscopy

A Study of Self-Healing Polymer Nanocomposites with Filler Effect

Has Graphene lived Up to the Hype?

Safety, Toxicology, and Regulatory Science of CT Nano‐Contrast Agents in Radiology

Quantum Dots in Oral Diagnostics and Theranostics:Promise and Preclinical Status

Quantum Dots in Oral Diagnostics and Theranostics: Promise and Preclinical Status

Read more of it

Publish your article