Biosynthesis, characterization of gold nanoparticles using M. indica leaf extractand their anticancer activity

Rajiv Dutta

International journal of Nanobiotechnology

Biosynthesis, characterization of gold nanoparticles using M. indica leaf extractand their anticancer activity

Rajiv Dutta

Abstract

The present study involves the novel approach for the synthesis of nanomaterial holds infinite possibilities as nanotechnology has a major impact on medicine and its application. Leaf extract of Mangiferaindicais a very good bioreductant for gold chloride (HAuCl4·4H2O) which leads to the synthesis of gold nanoparticles. Leaf extract of Mangiferaindicawas mixed with gold chloride (HAuCl4·4H2O) and UV-vis spectroscopy was used to detect the synthesis of nanoparticles. TEM and FESEM were used for size, shape and structural morphology of synthesized nanoparticles. Synthesized gold nanoparticles were in range of less than ~75nm and hexagonal in shape. The gold nanoparticles also showed potent cytotoxic effect against A549 lung cancer cell lines with an IC 50 value of 59 μg/ml/24 h by the MTT assay Keywords: Biosynthesis, Characterization, Cytotoxicity Gold chloride, Nanotechnology

Full text

The full text of this article is available to subscribers.

On a subscribing campus you are let in by network address, with no login at all.

One-off purchase. Permanent access to this article, no account needed.

A year of online access to every article in International journal of Nanobiotechnology. Or choose several journals →

Article details

Biosynthesis, characterization of gold nanoparticles using M. indica leaf extractand their anticancer activity

Abstract

Read more of it

Publish your article

Abstract

Related articles

Intelligent Nanobots: Real-Time Framework for Molecular Pollution Detection and Health Risk Mitigation

An investigation into the use of nanotechnology in medical-military applications

An Overview on Nanomaterial-Enabled Electronic Skin for Physiological Sensing and Biomedical Use

Nanobiotechnology in the Real World: How Lab Ideas Affect Real Life

Enhancing the strength and flexibility of crowns and bridges: advances in materials, design, and nanotechnology.

Xerostomia and Salivary Gland Hypofunction: From Pathophysiology to Nanotechnology‑Enabled Regenerative Therapies

Read more of it

Publish your article