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By: Kanishka Khatri, Jheel Toshniwal, Anjali Yogi, and Sanjeev Patwa.
Animal testing has played a crucial role in medical research, leading to major advancements like vaccines, treatments, and diagnostic methods. However, this remains a contentious issue due to ethical concerns regarding animal welfare, rights, and suffering. The growing awareness of animal sentience and the potential for pain and distress have intensified ethical debate, prompting efforts to refine regulatory frameworks and research practices. While principles, such as the “Three Rs” (Reduction, Refinement, and Replacement) aim to minimize animal use and suffering, complete reliance on alternative methods, such as in vitro and in silico techniques, is not yet feasible due to the complexity of biological systems. This paper explores the historical evolution of animal testing, its indispensable role in advancing medical knowledge, and its ethical dilemmas. Collaborative efforts among researchers, policymakers, and ethics committees are essential to address these challenges and ensure ethical treatment of animals while fostering innovation in medical research.
Keywords: Animal testing, medical research, ethical considerations, three Rs principles, scientific necessity, ethical theories, alternative methods, biomedical advancements
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