Ansh Kumar Bhuva, Jenish Parvadiya, Kabhi Khanna, Tazmeen Shafi | International Journal of Composite Materials and Matrices | Vol 12, Issue 02 | pp. 16-23 | ISSN: 2582-435X
Abstract
Due to the limits of conventional grafts, large bone deficiencies resulting from illness or trauma continue to be a significant clinical challenge. Autografts, while osteoconductive and osteoinductive, are limited by donor availability and morbidity, and allografts/xenografts carry risks of immune rejection and disease transmission. In contrast, 3D printing (additive manufacturing) enables fabrication of patient-specific bone scaffolds with controlled architecture, composition, and bioactivity. Using techniques, like selective laser sintering (SLS), stereolithography (SLA), and fused deposition modelling (FDM), as well as materials ranging from biodegradable polymers to bioactive ceramic, recent developments have produced innovative porous implants. This review surveys the state of 3D-printed bone grafts, covering printing methods, scaffold materials (e.g., PCL, PLA, ceramics, composites), and strategies to enhance biological performance (growth-factor loading, coatings, cell-seeding). We discuss preclinical and emergingclinical applications, along with current challenges (e.g., vascularization, mechanical strength, regulatory hurdles) and future innovations (4D-printing, smart biomaterials, AI-guided design). By integrating mechanical and biological cues, 3D-printed scaffolds promise to overcome many shortcomings of existing grafts, paving the way for truly personalized bone regeneration.
Keywords:3D printing, bone tissue engineering, bone regeneration, additive manufacturing, biodegradable scaffolds, personalized medicine
Keywords
3D Printing, bone regeneration, additive manufacturing, biodegradable scaffolds, bone tissue engineering
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How to cite this article
@article{BhuvaAK2026,
author = {Ansh Kumar Bhuva and Jenish Parvadiya and Kabhi Khanna and Tazmeen Shafi},
title = {Revolutionizing Bone Grafting: A Survey of 3D Printed Solutions},
journal = {International Journal of Composite Materials and Matrices},
year = {2026},
volume = {12},
number = {02},
pages = {16--23},
issn = {2582-435X},
url = {https://journalspub.com/publication/ijcmm/article=27008}
}