By: Nilkanta Barmana, Pankaj Kesharia, and Sudip Simlandib
This work presents an analytical solution to provide a real time variation in increase of temperature during laser-treatment of cancer tissues. Energy conservation equation is used to model the respective laser treatment process considering application of the laser and related heat loss as heat source terms. The present prediction is validated first with an existing literature, and extended the same to predict the effect of different process variables such as laser intensity, beam diameter, tissue absorption coefficient, blood perfusion rate, and surrounding heat loss on history of temperature during interaction of laser-tissue. It is observed that temperature of the tissues increases with an increase in the laser intensity and with a decrease in the blood perfusion factor. The effect of other process parameters on the history of temperature is also presented as a parametric study. In short, the present model is able to provide a real time variation of temperature during laser treatment of cancer tissues under various process parameters, which is a helpful model in medical treatment of cancer tissues.
Keywords: Photo-thermal therapy, cancer tissue, laser, analytical model, blood perfusion
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