Rizwan Arif, Neha Sahu | International Journal of Chemical Engineering and Processing | Vol 10, Issue 02 | pp. 9-14 | ISSN: 2455-5576
Abstract
The rapidly evolving field of drug development continually seeks innovative methodologies to enhance the efficiency, specificity, and scalability of molecular synthesis. This paper explores recent advancements in synthetic chemistry, focusing on techniques that have shown significant promise in addressing the challenges faced in drug discovery and development. Automated Synthesis: The advent of machine learning and artificial intelligence (AI) in synthetic chemistry has led to the development of automated synthesis platforms. These systems can optimize reaction conditions, predict synthetic routes, and accelerate the discovery of new compounds. Biocatalysis: Utilizing enzymes as catalysts offers a green and highly specific alternative to traditional chemical synthesis. Advances in enzyme engineering and directed evolution have expanded the substrate scope and improved the efficiency of biocatalytic processes, making them integral to modern drug synthesis. Photoredox Catalysis: This method harnesses light to drive chemical reactions, enabling the formation of complex molecules under mild conditions. Recent innovations in photocatalyst design and reaction optimization have significantly broadened the applicability of photoredox catalysis in drug development. Green Chemistry: Sustainable approaches to synthesis are increasingly prioritized, with a focus on reducing waste, minimizing energy consumption, and utilizing renewable resources. Innovations in green chemistry are critical to developing environmentally friendly and economically viable synthetic methods. The synthesis of drug candidates has become more sophisticated with these innovative approaches, facilitating the discovery of new therapeutics and improving the efficiency of drug development pipelines. This paper provides a comprehensive overview of these advancements, highlighting their impact on the pharmaceutical industry and future directions for research.
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How to cite this article
@article{ArifR2024,
author = {Rizwan Arif and Neha Sahu},
title = {Innovative Approaches to Molecular Synthesis for Drug Development},
journal = {International Journal of Chemical Engineering and Processing},
year = {2024},
volume = {10},
number = {02},
pages = {9--14},
issn = {2455-5576},
url = {https://journalspub.com/publication/ijocep/article=14665}
}