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7 articles for “and NMR Spectroscopy”
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Major Analytical Problems in Current Pharmaceutical Drug Products
Abstract: Substances of pharmaceutical drug products go through thorough analyses to check the safety, efficacy as well as the quality of the final product. There are a number of shortcomings even though much has been done in the analytical methods used in recalls. Such challenges are those concerning method validation, sensitivity, specificity, reproducibility, and regulation. This article on major analytical problems in current pharmaceutical drug products outlines major limitations in the …
Published in International Journal of Analytical and Applied Chemistry · Vol. 11, Issue 1, 2025 · pp. 29–39 Read article
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Synthesis, Structural Elucidation, and Antimicrobial Screening of a Cobalt (II) Coordination Compound Derived from a Thiophene-Containing Schiff Base
Abstract: Abstract An N, O-chelating azomethine Schiff base ligand (HL), chemically identified as 2-{[(thiophen-2-yl) methylidene] amino} benzoic acid, was synthesized by an equimolar condensation reaction between thiophene-2-carbaldehyde and anthranilic acid in absolute ethanol in the presence of a catalytic amount of acetic acid. The corresponding cobalt (II) complex, formulated as [Co(L)₂] · 2H₂O, was prepared by refluxing two equivalents of the ligand with one equivalent of cobalt (II) acetate tetrahydrate in …
Published in International Journal of Analytical and Applied Chemistry · Vol. 12, Issue 2, 2026 · pp. 1–7 Read article
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Reactivity of Niobium(V) ComplexTowards Hydroxamate Ligands
Abstract: A niobium(V) complex with the composition [NbCl(OC₆H₄CH(CH₃)₂-2)₄] was synthesized by reacting niobium pentachloride with four equivalents of 2-isopropylphenol in carbon tetrachloride as a solvent, yielding the product in good quantity. The complex was characterized using elemental analysis, molar conductance measurements, IR spectroscopy, ¹H and ¹³C NMR spectroscopy, and mass spectrometry. Spectroscopic results indicate that the complex exists in a dimeric form, with bridging occurring through isopropylphenoxo ligands. X-ray diffraction analysis …
Published in International Journal of Energetic Materials · Vol. 12, Issue 1, 2026 · pp. 1–6 Read article
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Heterocyclic Oxadiazole Derivatives Through Various Spectroscopic Techniques as UV, IR.
Abstract: The study focuses on the synthesis, characterization, and analysis of heterocyclic oxadiazole derivatives using various spectroscopic techniques, including UV-visible (UV-Vis) spectroscopy and infrared (IR) spectroscopy. Oxadiazoles are a type of five-membered heterocyclic compounds with nitrogen and oxygen atoms. They are important in medical chemistry and materials research and show a wide range of biological activity. The synthesized oxadiazole derivatives were characterized through UV-Vis spectroscopy to investigate their electronic transitions and …
Published in International Journal of Analytical and Applied Chemistry · Vol. 10, Issue 1, 2024 · pp. 1–8 Read article
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Synthesis and Evaluation of Antifungal Properties of 2-((4-((6phenylimidazo[2,1-b][1,3,4]thiadiazole-2-yl)methoxy)phenoxy)methyl)-6-phenylimidazo[2,1-b][1,3,4] thiadiazole Derived from Hydroquinone
Abstract: Thiadiazole, a heterocyclic core, has garnered significant interest from chemists seeking novel therapeutic agents. The synthetic route for the target compounds is depicted in Scheme 1. The compounds were synthesized with favorable yields through the condensation of hydroquinone with various organic reagents. They underwent physical characterization and were analyzed using spectroscopic methods, including infrared (FTIR) and NMR (1H, 13C) spectroscopy. The FT-IR spectrum of the product exhibited a ν(C=N) absorption …
Published in International Journal of Environmental Chemistry · Vol. 12, Issue 1, 2026 · pp. 76–82 Read article
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Synthesis and Biological Evaluation of a Novel Schiff Base Ligand [(E)-2,4-Dichloro-6-(1-((4-Fluorophenyl) iminoethyl)phenol] and Its Metal Complexes
Abstract: The study involved the synthesis and characterization of a novel bidentate Schiff base ligand, [(E)-2,4-dichloro-6-(1-((4-fluorophenyl) iminoethyl) phenol)], derived from 1-(3,5-dichloro-2-hydroxyphenyl) ethanone and 4-fluoroaniline. Transition metal salts (Co (II), Cu (II), Fe (II), Zn (II), Ni (II), Mn (II), Ag (II), Cd (II), Hg (II), and Pd (II)) were used to synthesize metal complexes. The chemicals used were of analytical grade, and solvents were distilled before use. Characterization involved UV, IR, …
Published in International Journal of Analytical and Applied Chemistry · Vol. 10, Issue 1, 2024 · pp. 26–35 Read article
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Commercial Scale Quantification of Lignin
Abstract: Lignin, an aromatic biopolymer, in the terrestrial lignocellulosic biomass constitutes the single largest and sustainable source of biofuels and biochemicals. The recalcitrant nature of lignin is a hindrance to its chemical or biochemical conversion. Moreover, its insolubility in water too is a major challenge in its quantification which is a necessary step prior to and after its conversion. Though there are celebrated quantification methods like the classical Klason lignin method …
Published in International Journal of Environmental Chemistry · Vol. 11, Issue 2, 2025 · pp. 20–25 Read article