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58 articles for “drug targets”
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Targeted Drug Delivery and Nanotechnology: An Overview
Abstract: Targeted drug delivery is a special form of drug delivery system where the medicament is selectively delivered or targeted only its site of action and keeping rest part of the body relatively free. Drug is a substance used for prevention, diagnosis, treatment and cure of a disease.Drug and medicine are synonym of each other and commonly used interchangeable. But there is minor difference in between both the terms. Drug is …
Published in International Journal of Composite and Constituent Materials · Vol. 6, Issue 1, 2020 · pp. 34–38 Read article
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Microscopic Avengers: The Rise of Nanorobots in Biomedical Engineering
Abstract: Nanorobotics is an emerging field at the intersection of nanotechnology and robotics, offeringa promising new frontier in biomedical engineering. Nanorobots, at the scale of a fewhundred nanometres, are designed to perform a variety of tasks within the human body,ranging from targeted drug delivery to precise surgical procedures. This article explores theevolution, design, functionality, and applications of nanorobots in biomedical engineering,highlighting their potential to revolutionize healthcare.The evolution of nanorobots has seen …
Published in International Journal of Nanomaterials and Nanostructures · Vol. 9, Issue 2, 2023 · pp. 10–15 Read article
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Nanotechnology Based Drug Delivery System for Cancer Therapy
Abstract: Nanotechnology has the potential to revolutionize cancer diagnosis and therapy. Advances in protein engineering and material science have contributed to novel nanoscale targeting approaches that may bring new hope to cancer patients. Several therapeutic nanocarriers have been approved for clinical use. However, to date, there are only a few clinically approved nanocarriers that incorporate molecules to selectively bind and target cancer cells. This review examines some of the approved formulations …
Published in International journal of Nanobiotechnology · Vol. 5, Issue 2, 2019 · pp. 8–36 Read article
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In silico evaluation for the repurposing of antiviral drugs towards multiple targets of monkey pox viral disease
Abstract: Objective: Monkeypox is a growing public health problem. The disease is caused by the monkeypox virus. The latest epidemic has been linked to previously unknown mutations and variations. Tecovirimat is a poxvirus medication that has been licenced by the US Food and Drug Administration (FDA). Otherwise, there is little pharmacopoeia and scientific interest inmonkeypox. Computational screening and molecular interactions were used in this work to investigate the possible repurposing of …
Published in International Journal of Animal Biotechnology and Applications · Vol. 9, Issue 1, 2023 · pp. 22–32 Read article
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Automated Diagnosis and Drug Delivery System for Colon Cancer Using Biosensors and Nanostructures
Abstract: Colorectal cancer stands as a significant global health challenge, necessitating innovative approaches for early detection and effective treatment. This paper presents a novel framework for addressing this challenge by integrating biosensors with nano materials and nano structures to create an automated system for colon cancer diagnosis and treatment. The proposed system leverages the unique properties of biosensors for real-time disease detection and the advanced capabilities of nano materials and nano …
Published in International Journal of Nanomaterials and Nanostructures · Vol. 10, Issue 1, 2024 · pp. 10–23 Read article
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Targeted Nanotherapy and Advanced Biosensing: A Novel Approach to Preventing and Treating Fibrodysplasia Ossificans Progressiva
Abstract: Fibrodysplasia ossificans progressiva (FOP) is an exceptionally rare and debilitating genetic disorder marked by the gradual transformation of soft tissues into bone, severely impairing movement and reducing lifespan. This review delves into the potential of cutting-edge nanotherapy and advanced biosensing technologies as novel strategies for both preventing and treating FOP. Nanotechnology could help make targeted drug delivery systems and real-time monitoring tools that can precisely target the mutant ACVR1 gene, …
Published in International journal of Nanobiotechnology · Vol. 10, Issue 2, 2024 · pp. 11–18 Read article
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Review Article on: Nanoemulsion based intranasal drug delivery to Brain
Abstract: The bloodbrain barrier (BBB) controls and restricts the entry of therapeutic medications because it plays a critical role in protecting the brain from toxins.Nasal medicine administration allows for immediate drug delivery into the brain through the nose-to brain pathway.avoiding both the first pass impact and the blood-brain barrier. Various novel and promising formulation approaches have been explored for drug targeting to the brain by nasal administration. Nanoemulsions have the potential …
Published in International journal of Nanobiotechnology · Vol. 10, Issue 1, 2024 · pp. 17–24 Read article
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Revolutionizing Cancer Treatment through Nanoparticle-Based Drug Delivery Systems
Abstract: Cancer is a leading cause of death worldwide, and the treatment options available have significant limitations, including toxicity, low efficacy, and drug resistance. Nanotechnology has made significant progress in recent years, resulting in the emergence of drug delivery systems based on nanoparticles that are used for cancer treatment. These systems offer numerous benefits, including targeted drug delivery, increased drug stability, and reduced toxicity. Nanoparticle-based drug delivery systems are a promising …
Published in International journal of Nanobiotechnology · Vol. 8, Issue 2, 2022 · pp. 8–15 Read article
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Cryogenic Electron Microscopy Reveals Conformational Dynamics and Catalytic Mechanisms of Human Fatty Acid Synthase in De Novo Lipid Biosynthesis
Abstract: Fatty acid synthase (FASN) is a multifunctional homodimeric enzyme central to de novo fatty acid synthesis in mammals. Recent cryogenic electron microscopy (cryo-EM) studies have illuminated the structural basis of FASN catalysis, revealing multiple conformational states throughout the synthesis cycle. These findings show that the acyl carrier protein (ACP) domain dynamically shuttles substrates between spatially separated active sites, while the condensing and modifying regions remain structurally stable. In contrast to …
Published in International Journal of Analytical and Applied Chemistry · Vol. 12, Issue 2, 2026 · pp. 8–25 Read article
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Melanoma’s Nemesis: Assessing the Pharmacological Impact of Curcumin and its Analogues as Inhibitors of Identified Biomarkers Via Network Pharmacology
Abstract: Objectives: Since the advent of next-generation sequencing, melanoma has been recognized as an immensely heterogeneous disease, leading to the discovery of numerous underlying genetic drivers over time. Bioinformatic and machine learning analyses have become increasingly prevalent in risk stratifying melanoma patients with high accuracy, leveraging genetic, clinical, and histopathological inputs. Via various research curcumin has been identified and also shown therapeutic efficacy in Melanoma. In order to reveal the interactions …
Published in International Journal of Applied Nanotechnology · Vol. 9, Issue 1, 2023 · pp. 33–44 Read article
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In-Vitro Evaluation of Control Release of Drug with Carbon Based Nanomaterials
Abstract: Nanomaterials have been introduced as a novel & interesting materials due to their advance properties & their use in nanotechnology applications like nano-sensors, nano-chips, control & targeted drug delivery, diagnosis, gene therapy. These all possibilities are due to their physico-chemical & multifunctional biological characteristics. In medicine, control release of drug is a factor to reduce dosage form in revert reduce side effects. In this work, nanomaterials are using as a …
Published in International journal of Nanobiotechnology · Vol. 1, Issue 1-2, 2015 · pp. 14–18 Read article
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Nanomechanics in Medicine
Abstract: Nanomechanics, an emerging field at the intersection of nanotechnology and mechanics, holds great promise for revolutionizing medicine. This article explores the significant role of nanomechanics in various aspects of healthcare, including diagnostics, drug delivery, tissue engineering, and cancer detection.One of the key applications of nanomechanics in medicine is in the development of nanomechanical sensors for disease detection. These sensors can detect biomarkers associated with diseases such as cancer at very …
Published in International Journal of Applied Nanotechnology · Vol. 9, Issue 2, 2023 · pp. 22–26 Read article
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Revolutionizing Medicine: The Promising Future of Nanobiotechnology
Abstract: Nanobiotechnology is an emerging field that combines the principles of nanotechnology and biology to develop innovative solutions for various applications in medicine, such as drug delivery, imaging, and disease diagnosis. This piece presents a summary of the present status of nanobiotechnology and its capacity to transform the field of medicine. The article discusses the various nanomaterials used in nanobiotechnology, including nanoparticles, nanotubes, and nanofibers, and their properties that make them …
Published in International journal of Nanobiotechnology · Vol. 8, Issue 2, 2022 · pp. 1–7 Read article
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Doping and Its Impacts on the Properties of ZnO Nanocrystals: A Brief Review
Abstract: Research on zinc oxide (ZnO) has surged in recent years due to its extensive range of applications because its unique physical and chemical properties make it ideal for various uses, including acoustic devices, photocatalysis, pharmaceuticals, light-emitting diodes, solar cells and antibacterial agents. ZnO nanoparticles are particularly notable for their biocompatibility, low toxicity and stability, making them suitable for drug delivery and antiviral applications. The versatility of ZnO has led to …
Published in International Journal of Chemical Synthesis and Chemical Reactions · Vol. 10, Issue 1, 2025 · pp. 8–25 Read article
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Chemical Synthesis and Functional Engineering of Poly(lactide-co-glycolic acid) in Medicine
Abstract: Poly (lactide-co-glycolic acid) (PLGA) is one of the most extensively studied biodegradable polymers in modern medicine due to its excellent biocompatibility, tunable degradation behavior, and regulatory acceptance. Originally introduced in resorbable surgical sutures and implants, PLGA has evolved into a highly versatile platform for controlled and targeted drug delivery systems. This review presents a comprehensive analysis of PLGA’s chemical structure, synthesis methods, physicochemical properties, degradation mechanisms, and established clinical applications. …
Published in International Journal of Chemical Synthesis and Chemical Reactions · Vol. 12, Issue 1, 2026 Read article
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An Energetic Materials for Sustainable Solutions
Abstract: Nanomaterials are typically described as engineered substances possessing at least one dimension between 1 and 100 nm. Materials at the nanoscale display distinctive or enhanced characteristics, such as increased chemical reactivity, superior sensing performance, and improved mechanical properties. Nanotechnology provides a straightforward, rapid, clean, and cost-effective approach for synthesizing a wide range of organic compounds, encouraging many researchers to transition from conventional synthetic techniques. This article aims to highlight the …
Published in International Journal of Energetic Materials · Vol. 12, Issue 1, 2026 · pp. 7–12 Read article
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Chemical Engineering Aspects of Carrageenan Hydrogel–Silver Composite Systems: Synthesis, Structure, and Performance
Abstract: This review presents a green chemistry-driven strategy for the synthesis, design, and chemical engineering of carrageenan-based hydrogel matrices embedded with green-synthesized silver nanoparticles (AgNPs) for advanced biomedical and pharmaceutical applications. Silver nanoparticles were fabricated through an environmentally benign route employing natural biopolymeric reducing and stabilizing agents, eliminating the need for hazardous chemical reagents and minimizing ecological impact. The synthesized AgNPs were subsequently incorporated into κ-carrageenan hydrogel networks under controlled physicochemical …
Published in International Journal of Chemical Engineering and Processing · Vol. 12, Issue 1, 2026 · pp. 7–27 Read article
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Chemical Engineering Aspects of Carrageenan Hydrogel–Silver Composite Systems: Synthesis, Structure, and Performance
Abstract: This review presents a green chemistry–driven strategy for the synthesis, design, and chemical engineering of carrageenan-based hydrogel matrices embedded with green-synthesized silver nanoparticles (AgNPs) for advanced biomedical and pharmaceutical applications. Silver nanoparticles were fabricated through an environmentally benign route employing natural biopolymeric reducing and stabilizing agents, eliminating the need for hazardous chemical reagents and minimizing ecological impact. The synthesized AgNPs were subsequently incorporated into κ-carrageenan hydrogel networks under controlled physicochemical …
Published in International Journal of Chemical Engineering and Processing · Vol. 12, Issue 1, 2026 · pp. 7–28 Read article
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Nanomaterials in Modern Medicine: Synthesis,Applications, and Future Prospects
Abstract: Nanomaterials have significantly transformed the biomedical landscape, offering novelsolutions for diagnosis, treatment, and disease prevention. Their distinct physicochemicalcharacteristics such as a high surface area-to-volume ratio, tunable surface chemistry, andimproved bioavailability enable precise interactions with biological systems at the molecularlevel. This review presents a comprehensive examination of the synthesis methods andcharacterisation techniques employed to develop biomedical-grade nanomaterials, highlightingtheir structural and functional optimisation for clinical applications. Key areas of applicationdiscussed include targeted …
Published in International Journal of Nanomaterials and Nanostructures · Vol. 11, Issue 2, 2025 Read article
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Nanorobotics in Cancer Treatment: A Study
Abstract: Cancer, a complex and devastating disease, continues to plague humanity. There have been great advancements achieved in conventional treatments, such as chemotherapy and radiation; however, these treatments frequently come with serious adverse effects and limited efficacy against certain types of tumors. In the relentless pursuit of more targeted and effective therapies, nanorobotics has emerged as a promising frontier. This article explores the potential of nanorobots in revolutionizing cancer treatment, drawing …
Published in International Journal of Nanomaterials and Nanostructures · Vol. 11, Issue 1, 2025 · pp. 44–52 Read article