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By: Dr. Kazi Kutubuddin Sayyad Liyakat.
Professor and Head, Department of Electronics and Telecommunication Engineering, Brahmdevdada Mane Institute of Technology, Solapur, Maharashtra, India
Biopolymers – naturally derived macromolecules, such as polysaccharides, proteins, and polyhydroxyalkanoates – have emerged as a versatile toolbox for next-generation medical technologies. Their intrinsic biocompatibility, tunable degradation kinetics, and capacity for molecular functionalization enable the design of devices that communicate with living tissue rather than merely coexist with it. This review synthesizes recent advances across four inter-related fronts: (i) drug-delivery carriers, where chitosan-based nanoparticles and hyaluronic-acid hydrogels provide stimulus-responsive release profiles; (ii) tissue-engineering scaffolds, exemplified by silk-fibroin matrices and 3D-printed alginate-gelatin composites that recapitulate native extracellular-matrix cues; (iii) wound-care and regenerative dressings, in which collagen-laden electrospun fibers accelerate hemostasis and promote angiogenesis; and (iv) implantable devices and bio-inks, including poly-l-lactic-acid (PLA) and poly-l-glycolic-acid (PLGA) microsystems that integrate seamlessly with host biology. By juxtaposing mechanistic insights (e.g., polymer– cell adhesion, enzymatic degradation pathways) with translational case studies (clinical trials of PLGA sutures, FDA-approved alginate wound gels), the review highlights how rational polymer engineering bridges the gap between bench-side synthesis and bedside impact. Critical challenges – batch-to-batch variability, sterilization‐induced property loss, and regulatory complexities – are examined, and a forward-looking roadmap is proposed that leverages hybrid biopolymer-synthetic composites, bio-orthogonal click chemistries, and AI-guided material optimization to realize truly “smart” medical implants.
Citation:
Refrences:
- Polymer Applications in Energy Generation and Storage: A Forward Path. J Nanoscience Nanoeng Appl. 2024;14(2):31–9.
- Sayyad L. Review of Biopolymers in Agriculture Application: An Eco-Friendly Alternative. Int J Compos Constit Mater. 2024;10(1):50–62.
- Mulla NR, Liyakat KKS. Pipeline Pressure and Flow Rate Monitoring Using IoT Sensors and ML Algorithms to Detect Leakages. Int J Artif Intell Mech Eng. 2025;1(1):20–30.
- Mulla NR, Liyakat KKS. Nuclear Energy: Powering the Future or a Risky Relic. Int J Sustain Energy Thermoelect Gener. 2025;1(1):52–63.
- Mulla NR. Sensor-based Aircraft Wings Design Using Airflow Analysis. Int J Image Process Smart Sensors. 2025;1(1):55–65.
- Sayyad KKS. Cardiovascular Modeling with Computational and Mathematical Methods. Res Rev J Bioinform. 2025;12(2):1–11.
- Mulla NR, Sayyad KKS. Air Flow Analysis in Sensor-Based Aircraft Wings Design. Recent Trends Fluid Mech. 2025;12(2):29–39.
- Mulla NR, Sayyad KKS. IoT Sensors to Monitor Pipeline Pressure and Flow Rate Combined with ML Algorithms to Detect Leakages. Recent Trends Fluid Mech. 2025;12(2):40–48.
- Mulani AK, Shaikh HT, Liyakat KKS. Nuclear Power Generation Using UO2 Materials. J Adv Elect Eng Devices. 2025;3(2):27–40.
- Shaikh HT, Liyakat KKS. Empowering the IoT: The Study on Role of Wireless Charging Technologies. J Control Instrum Eng. 2025;11(2):29–39.
- Shaikh HT, Liyakat KKS. Pre-Detection Systems Transfiguring Intoxication and Smoking Using Sensor and AI. J Instrum Innov Sci. 2025;10(2):19–31.
- Desai VA. AI and Sensor Systems Revolutionizing Intoxication and Smoking Pre-Detection. J Control Instrum. 2025;16(3):15–26.
- Shaikh HT. The Future of Coastal Resilience: Harnessing Satellite Technology. Adv Res Commun Eng Innov. 2025;28–36. Available from: https://matjournals.net/engineering/index.php/ARCEI/article/view/2281.
- Shaikh HT, Liyakat KKS. Sensor-based Intelligent Wearable Glasses. J Digit Circuitry Innov Elect Devices. 2025;1(2):16–24.
- Sayyad KKS. Nanorobots: The Fight against Cholesterol. Nano Trends J Nano Technol Appl. 2025;27(2). Available from: https://journals.stmjournals.com/nts/article=2025/view=205244
- Shaikh HT, Liyakat KKS. Pre-Detection Systems Transfiguring Intoxication and Smoking Using Sensor and AI. J Instrum Innov Sci. 2025;10(2):19–31.
- Mulani AK. Microwave Signals: A New Frontier in Non-Invasive Medical Diagnostics: A Study. J Microw Eng Technol. 2025;12(3):27–41.
- Mulani AK. Revolutionizing Optical Fibre Field Distribution with Linear Finite Element Method. Trends Opto-electro Opt Commun. 2025;15(3):31–41.
- Shaikh HT, Liyakat KKS. Robust Access Control Mechanisms in IoT Security using VHDL Programming. J VLSI Des Signal Process. 2025;11(2):31–40.
- Mulani AK. Optical Fibre Pressure Sensor in Medicine: A Study. Recent Trends Sensor Res Technol. 2025;12(3):18–27.
- Abhangrao CM, Liyakat KKS. A study on hybrid intelligence in COBOT. J Mech Robot. 2025;10(2):15–29.