Dr. Kazi Kutubuddin Sayyad Liyakat | International Journal of Polymer Science and Engineering | Vol 11, Issue 02 | pp. 1-15 | ISSN: 2455-8745
Abstract
Biopolymers – naturally derived macromolecules, such as polysaccharides, proteins, and polyhydroxyalkanoates – have emerged as a versatile toolbox for next-generation medical technologies. Their intrinsic biocompatibility, tunable degradation kinetics, and capacity for molecular functionalization enable the design of devices that communicate with living tissue rather than merely coexist with it. This review synthesizes recent advances across four inter-related fronts: (i) drug-delivery carriers,where chitosan-based nanoparticles and hyaluronic-acid hydrogels provide stimulus-responsive release profiles; (ii) tissue-engineering scaffolds,exemplified by silk-fibroin matrices and 3D-printed alginate-gelatin composites that recapitulate native extracellular-matrix cues; (iii) wound-care and regenerative dressings,in which collagen-laden electrospun fibers accelerate hemostasis and promote angiogenesis; and (iv) implantable devices and bio-inks,including poly-l-lactic-acid (PLA) and poly-l-glycolic-acid (PLGA) microsystems that integrate seamlessly with host biology. By juxtaposing mechanistic insights (e.g., polymer– cell adhesion, enzymatic degradation pathways) with translational case studies (clinical trials of PLGA sutures, FDA-approved alginate wound gels), the review highlights how rational polymer engineering bridges the gap between bench-side synthesis and bedside impact. Critical challenges – batch-to-batch variability, sterilization‐induced property loss, and regulatory complexities – are examined, and a forward-looking roadmap is proposed that leverages hybrid biopolymer-synthetic composites, bio-orthogonal click chemistries, and AI-guided material optimization to realize truly “smart” medical implants.
Keywords
Biopolymers, medical applications, drug-delivery carriers, tissue-engineering scaffolds, wound-care, regenerative dressings
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How to cite this article
@article{LiyakatDKKS2026,
author = {Dr. Kazi Kutubuddin Sayyad Liyakat},
title = {Biopolymers in Medical Application: A Study},
journal = {International Journal of Polymer Science and Engineering},
year = {2026},
volume = {11},
number = {02},
pages = {1--15},
issn = {2455-8745},
url = {https://journalspub.com/publication/ijpse/article=22990}
}