2 publications

• Published Subscription 27 Dec 2024

  Quantification of Morphine, Codeine, and Dihydrocodeine in Carissa carandas Leaves and Fruit Using LC-MS/MS: The Impact of Drying on Alkaloid Concentration

  By Meghna Choudhary, Amit Kumar, Ashok Singh

  Abstract: This study presents a method for quantifying morphine, codeine, and dihydrocodeine in Carissa carandas (Karonda) leaves and fruit, employing morphine-D3 as an internal standard (1 µg/mL) to ensure accuracy. Samples are prepared at 25 ng/mL and extracted using solvent techniques, with an optional solid-phase extraction step to mitigate matrix effects. Quantification is conducted via LC-MS/MS, providing robust sensitivity. Results show that drying concentrates these alkaloids, particularly morphine in fruit, due …

  Published in International Journal of Environmental Chemistry · Vol. 11, Issue 1, 2025 · pp. 49–61 Read article →

• Published Subscription 1 Oct 2024

  Comparative Analysis of Essential Oil Composition and Antioxidant Activity in Carissa carandas L. Fruits from Diverse Indian Regions Using GC-MS Metabolomics

  By Meghna Choudhary, Amit Kumar, Nupur Rani, Mani Ratnam, Jayesh Yadav

  Abstract: Essential oils of Carissa carandas fruits collected from six different regions in India characterized by diverse climatic conditions were investigated for their chemical composition, oil yield diversity and antioxidant activity. The lowest (0.08%) and the highest (19.32%) of each compound in essential oils were demonstrated in fruit samples from Dehradun and Rajasthan, respectively. GC-MS based analysis identified 33 compounds. The main components were limonene, β-myrcene, γ-terpinene, β-linalool, terpinen-4-ol, eugenol, β-element, …

  Published in International Journal of Agrochemistry · Vol. 10, Issue 2, 2024 · pp. 8–16 Read article →