International journal of Thermodynamics and Chemical Kinetics

Thermal Decomposition Kinetics of Mefenamic Acid Crystals

  1. S. Ramukutty
  2. E. Ramachandran ✉

Abstract

Single crystals of mefenamic acid were crystallized by gel growth method for the first time in literature. Crystal structure was confirmed using single crystal X-ray diffraction analysis. Kinetic analysis was made from the isothermal thermogravimetric analysis/differential thermal analysis (TGA/DTA) data using Coats–Redfern (CR) relation. Thermodynamic parameters were also determined. Arrhenius equation for mefenamic acid is k = 0.28 × 109 e–116551/RT mol–1s–1. Keywords: kinetic analysis, mefenamic acid, thermal analysis

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