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By: Deepanshi Sharma, Chanchal Malik, Mohammad Mehboob Ali Siddque, and Surya Prakash D.V..
1-3. B.Tech. Student, Department of Biotechnology, Meerut Institute
of Engineering and Technology, Meerut, Uttar Pradesh, India.
4. Assistant Professor, Department of Biotechnology, Meerut Institute
of Engineering and Technology, Meerut, Uttar Pradesh, India.
Withania somnifera (L.) Dunal, often referred to as Ashwagandha or Indian ginseng, is a renowned
medicinal herb widely utilized in traditional medical practices, especially Ayurveda, and it belongs to
the Solanaceae family. The plant has attracted considerable scientific interest because of its wide range
of pharmacological effects and therapeutic possibilities. Different sections of this plant, particularly the
roots and leaves, possess bioactive components that enhance its therapeutic properties. Many
experimental and clinical studies have shown that the plant possesses antioxidant, neuroprotective, anti-
inflammatory, anti-stress, and immunomodulatory properties. It has been used traditionally to boost
physical power, enhance mental performance, and support overall health. Recent studies also indicate
its possible involvement in controlling chronic issues like arthritis, neurodegenerative diseases,
diabetes, anxiety diseases, and cancer. The adaptogenic properties of W. somnifera assist the body in
managing physiological stress by balancing hormones and minimizing oxidative harm. Moreover, its
comparatively low toxicity and favourable tolerability render it a strong contender for extended
therapeutic application. Even with widespread traditional use and increasing scientific support,
additional rigorously designed clinical trials are necessary to determine standardized dosages, safety
profiles, and mechanisms of action. In general, it is a significant medicinal plant with substantial
potential for creating new herbal formulations and additional therapeutic agents.
Keywords: Withania somnifera, withanolides, adaptogen, diabetic, inflammatory
Citation:
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