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23 articles for “solubility”
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A Review Paper on Novel Lipid Nanoparticles for Enhanced Bioavailability of Bioactive Compounds in Breast Cancer Cell Lines
Abstract: Most bioactive compounds from natural products are heavily relied on drug development due to their biological, chemical and pharmacological properties. Some compounds exhibiting anticancer properties have also been reported. However, they present a challenge in achieving the effective absorption and delivery in the body. This is due to minimal bioavailability, fluctuation of plasma drug concentration, low tolerance, first-pass effect which leads to less desired efficacy. Therefore, this calls for an …
Published in International Journal of Composite and Constituent Materials · Vol. 10, Issue 1, 2024 · pp. 1–9 Read article
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Investigation of Thermo-Acoustic Properties of Ethanol-Cyclohexane Binary Mixture
Abstract: The density, viscosity, and speed of sound for ethanol-cyclohexane binary mixtures were determined across mole fractions ranging from 0.1 to 0.9 using an Anton Paar DSA 5000 M within the temperature span of 288.15–318.15 K. From these experimental measurements, several thermodynamic and acoustic properties, such as isentropic compressibility, relative association, free volume, relaxation time, Gibbs free energy of activation, internal pressure, and solubility parameter, were derived. These parameters serve as …
Published in International journal of Thermodynamics and Chemical Kinetics · Vol. 11, Issue 2, 2025 · pp. 1–14 Read article
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Investigation of the Compatibility of Binary and Ternary Polymer Systems
Abstract: We have obtained mechanical strength of materials as a result not by synthesizing new polymers, but by using industrial polymers. We have developed a technology for obtaining new composite materials based on industrial multi-tonnage polymers of high-strength polyethylene (HSPE), polyvinyl chloride (PVC), polyurethane thermoplastic elastomer (DUTEP), butyl rubber (BR), chlorocarboxylate polyethylene (CCPE), ethylene propylene rubber (EPR). To obtain a composition from these polymers, their mixture compatibility was first determined using …
Published in International Journal of Metallurgy and Alloys · Vol. 12, Issue 1, 2026 · pp. 44–56 Read article
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Major Analytical Problems in Current Pharmaceutical Drug Products
Abstract: Substances of pharmaceutical drug products go through thorough analyses to check the safety, efficacy as well as the quality of the final product. There are a number of shortcomings even though much has been done in the analytical methods used in recalls. Such challenges are those concerning method validation, sensitivity, specificity, reproducibility, and regulation. This article on major analytical problems in current pharmaceutical drug products outlines major limitations in the …
Published in International Journal of Analytical and Applied Chemistry · Vol. 11, Issue 1, 2025 · pp. 29–39 Read article
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Nanoelectronics, Nanoparticles and Nanotechnology in Treatment of Psychological Disorders
Abstract: Despite significant advancements in neuroscience, our understanding of brain functionality is far from complete, and ongoing research and testing are crucial for expanding our knowledge. With its billions of neurons and sophisticated neural networks, the brain is incredibly complicated, and scientists are always trying to find solutions for these problems. Here are a few reasons why continued research in the field of brain functionality is essential: The human brain is …
Published in International Journal of Environmental Chemistry · Vol. 10, Issue 1, 2024 · pp. 1–18 Read article
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General and Organic Chemistry Laboratory Experiments for Science , Pre-medical, and Pharmacy studentsChapter IV: Identification and Purification of Organic Compounds
Abstract: In order to identify an organic compound, a chemist needs to apply the suitable technique, depending on the compound state. Accordingly, melting point identification is applied for solids, boiling point for liquids, and sublimation for some compounds which have the tendency to sublime. On the other hand, When an organic compound is isolated from its natural source such as plants, it can be contaminated with some other undesirable compounds, called …
Published in International Journal of Analytical and Applied Chemistry · Vol. 12, Issue 1, 2026 · pp. 43–59 Read article
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Originative Approaches in Powder Formulation for Enhanced Therapeutic Efficacy
Abstract: Powder formulation is a cornerstone in the pharmaceutical industry, playing a vital role in improving drug efficacy and ensuring optimal therapeutic outcomes. However, traditional formulation methods often face significant challenges, such as poor solubility and low bioavailability, which can limit the effectiveness of many drugs. To address these issues, innovative strategies have emerged, including amorphous solid dispersions (ASDs), nanotechnology, and advanced manufacturing techniques like spray drying and hot melt etrusion. …
Published in International journal of Nanobiotechnology · Vol. 11, Issue 1, 2025 · pp. 1–10 Read article
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Microstructure and Mechanical Behavior of Microalloyed Forging Steels
Abstract: The microalloyed (MA) forging steels have been developed over the past several decades and they are gradually employed in the high-performance applications in many structural, automotive, and numerous engineering applications. The principle of microalloying contents in the Fe–C alloy system, thereby preferably combined with different mechanical, heat treatment, and microalloying solubility control the precipitation behaviors that lead to enormous opportunities to develop a new generation of high strength low alloy …
Published in International Journal of Metallurgy and Alloys · Vol. 11, Issue 2, 2025 · pp. 1–14 Read article
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Exploring the Boundless Applications of Chitosan: From Biomedical Marvel to Environmental Saviour
Abstract: Chitosan has attracted much interest because of its versatile properties and possible numerous usages in diversified industrial applications. Chitosan is having poor solubility in neutral and basic media and this is limiting its use. Chitosan is not a single polymer and do not have a defined structure. Chitosan is family of molecules with different composition, size & monomer units’ distribution and these characteristics have effect on the biological & technological …
Published in International Journal of Analytical and Applied Chemistry · Vol. 10, Issue 1, 2024 · pp. 1–9 Read article
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Recent Trends in Production, Characterization, and Utilization of Fungal Chitosan
Abstract: Chitosan is the second most abundant biopolymer in nature after cellulose that can be extracted from marine sources, as well as from agricultural waste products such as mushrooms or other fungal sources following chitin deacetylation. The consistent production of these glycans by fungi is unaffected by seasonal changes, allowing for precise process control. This results in a more consistent quality of the final product. Currently, crustacean shells and other marine …
Published in International Journal of Industrial Biotechnology and Biomaterials · Vol. 10, Issue 1, 2024 · pp. 23–31 Read article
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General and Organic Chemistry Laboratory Experiments for Science, Pre-medical, and Pharmacy Students – Chapter V: Organic Synthesis
Abstract: Organic synthesis can be classified into many types, including simple one-step synthesis, multi-step, one-pot, microwave, or green synthesis. Each type of synthesis takes place through a specific pathway depending on reactants involved, the reaction conditions, the catalyst, the protection group, and the duration of the reaction. In some cases, the required compound can be prepared by more than one procedure, and an expert chemist prefers the procedure by which the …
Published in International Journal of Analytical and Applied Chemistry · Vol. 12, Issue 2, 2026 · pp. 8–16 Read article
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Soil Fertility Assessment of Selected Villages in Bhuban Block, Dhenkanal, Odisha, India
Abstract: Using the Global Positioning System (GPS), the soil fertility condition of the Bhuban Block in the Dhenkanal district of Odisha was prepared. In 5 villages in the Bhuban Block of the Dhenkanal district, located in the central mid-tableland Agroclimatic region of Odisha, India, a study on the status of soil fertility was conducted. It is evident that the Bhuban Block’s several villages have varying textural classes, from loam to sand. …
Published in International Journal of Agrochemistry · Vol. 12, Issue 1, 2026 · pp. 7–10 Read article
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A review - Inhancing the Performance of Self-Curing Concrete Using Polyethylene Glycol as an Internal Curing Agent
Abstract: Abstract—This study examines the use of Polyethylene Glycol (PEG-400) as an internal curing agent in concrete, offering a sustainable alternative to traditional water-curing methods. The research addresses the challenge of water scarcity in the construction industry by introducing a self-curing system capable of retaining internal moisture to support prolonged cement hydration. PEG-400, a water-soluble polymer, was added to concrete mixes at different dosages to assess its influence on hydration, shrinkage …
Published in International Journal of Concrete Technology · Vol. 12, Issue 1, 2026 · pp. 1–6 Read article
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Effect of Plant Growth Regulator on Flowering and Yield Attributes of Litchi
Abstract: The study was carried out at the Horticulture Research Centre (HRC) Fruit Orchard, Regional Agricultural Research Station (RARS), Jamalpur, Bangladesh, during 2024–2025 to assess the influence of Plant Growth Regulator (PGR) (GA3) on flowering and yield attributes of litchi. The age of Litchi plants were 14–15 years old. The treatments are T1 = GA3 @ 50 mg/L on panicle before flower opening, T2 = GA3 @ 50 mg/L at 15 …
Published in International Journal of Plant Biotechnology · Vol. 12, Issue 1, 2026 · pp. 1–10 Read article
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Sulfur-Based Copolymers: Current Status and NewOpportunities in Synthesis and Product Applications
Abstract: Sulfur-based copolymers are fascinating materials with a wide range of applications. This reviewarticle delves into the synthetic aspects of sulfur copolymers, their characteristics, and theirapplications. Sulfur is a byproduct of refineries, produced in large quantities worldwide. Varioussulfur-based copolymers have been synthesized through inverse vulcanization, catalyst-induced low temperature inverse vulcanization, and polycondensation reactions. Researchers have studied a varietyof monomers, including benzoxazine moieties and sulfur-based systems with allylic or vinylicfunctionalities. The article …
Published in International Journal of Polymer Science and Engineering · Vol. 11, Issue 1, 2025 · pp. 10–36 Read article
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Effect of Soil pH on the Germination and Growth of Triticum aestivum (Wheat) and Zea mays (Maize)
Abstract: Because of its effects on nutrient availability, microbial activity, and the solubility of hazardous elements, all of which can have a substantial impact on crop productivity, soil pH is a crucial factor determining plant growth and development. Understanding how different pH levels affect the vegetative growth of crops is crucial for optimizing agricultural practices. This study examines the impact of soil pH – acidic, neutral, and alkaline – on the …
Published in International Journal of Agrochemistry · Vol. 11, Issue 2, 2025 · pp. 1–8 Read article
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Isocoreopsin and Glycogen Phosphorylase – An in-silico Interaction Study: A New Way to Tackle Type 2 Diabetes (T2D)†
Abstract: The activity of glycogen phosphorylase (GP) plays a crucial role in regulating glycogen metabolism, and its excessive activity has been closely linked to the pathogenesis of metabolic disorders, such as type 2 diabetes (T2D). Therefore, targeting GP inhibition has emerged as a significant therapeutic strategy for managing this disease. Current research focuses on the discovery and development of novel small molecules capable of suppressing GP activity. Among these, flavonoids have …
Published in International Journal of Environmental Chemistry · Vol. 11, Issue 1, 2025 · pp. 76–80 Read article
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Study of Corrosion of Ferrous and Non-Ferrous Metals in Aqueous Medium
Abstract: Metals, like ferrous and non-ferrous, interact on their interface to develop corrosion cells. The aqueous medium produces a hostile environment due to the availability of dissolved oxygen, acids, bases, salts, bio-waste, and effluents. The solubility of acidic gases oxide of carbon, oxide of nitrogen, and oxide of sculpture create an acidic medium for metal. These unfriendly environments accelerate corrosion reactions and metals exhibit uniform, galvanic, pitting, crevice, stress, and lynching …
Published in International Journal of Metallurgy and Alloys · Vol. 11, Issue 1, 2025 · pp. 44–50 Read article
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A Comparative Study of Intravenous Paracetamol and Intravenous Diclofenac for Post-operative Pain Relief
Abstract: Despite advancements reducing mortality rates, adverse effects such as pain, nausea, and vomiting remain prevalent and can hinder recovery. Pain is now considered the fifth vital sign, as defined by the International Association for the Study of Pain, and inadequate pain management can result in prolonged hospital stays, increased drug use, and delayed recovery. Effective postoperative pain control is crucial in preventing respiratory complications and facilitating early discharge and return …
Published in International Journal of Analytical and Applied Chemistry · Vol. 11, Issue 1, 2025 · pp. 50–56 Read article
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Assessing trends in Speciation of First-Row Transition Metals in Children's Playgrounds of Owerri, Nigeria
Abstract: Chemical species of metals affect toxicity but trends of these metals species in soils are less studied. This study examined the trends and variability of species of metals in soils from playgrounds within Owerri. Eighty-one composite soil samples from nine playgrounds were collected in dry and rainy season to reflect spatio-seasonal variability. Samples were characterized by standard methods in triplicates and then extracted sequentially. Concentrations of metal species were determined …
Published in International Journal of Green Chemistry · Vol. 11, Issue 1, 2025 · pp. 28–45 Read article