All articles
1733 articles
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Spermmediated gene transfer revisited: optimizing delivery, integration, and germline transmissionin large animal models
Abstract: Spermmediated gene transfer (SMGT) exploits the natural role of spermatozoa as DNA vectors to deliver exogenous genetic material to oocytes, potentially enabling economical production of transgenic large animals without complex embryo micromanipulation (1). Early proofofconcept studies established that mammalian sperm can bind, internalize, and protect exogenous DNA, leading to integration, expression, and germline transmission in various species, including pigs (24). Subsequent mechanistic work has challenged the traditional view of sperm …
Published in International Journal of Animal Biotechnology and Applications · Vol. 12, Issue 1, 2026 Read article
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Stem Cell and Cloning Technologies in Livestock Improvement: Advances, Applications, and Future Prospects for Sustainable Animal Production and Genetic Improvement
Abstract: Stem cell and cloning technologies have emerged as transformative tools for livestock improvement, enabling rapid genetic advancement, conservation of elite or endangered breeds, and development of animals with desirable production and health traits. Stem cells, including embryonic, adult, and induced pluripotent types, offer unparalleled potential due to their self-renewal, differentiation capacity, and versatility for genetic modification. Cloning technologies, particularly somatic cell nuclear transfer and embryo splitting, allow replication of superior …
Published in International Journal of Animal Biotechnology and Applications · Vol. 12, Issue 1, 2026 · pp. 44–53 Read article
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Animal Biotechnology: Finding a Balance Between New Ideas and Morality
Abstract: Animal biotechnology has become a revolutionary subject that combines genetics, farming, and medicine. It offers new ways to solve global problems like food security, disease management, and drug manufacturing. Scientists have used genetic engineering, cloning, transgenesis, and genome editing to make livestock more productive, generate animals that are immune to disease, and make useful scientific models. Transgenic animals are also being utilized more to make therapeutic proteins and help with …
Published in International Journal of Animal Biotechnology and Applications · Vol. 12, Issue 1, 2026 Read article
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Pediatric Nursing Interventions for Addressing Childhood Anxiety, Behavioral Disorders, and Emotional Well-Being
Abstract: Childhood anxiety, behavioral disorders, and emotional disturbances represent a growing global public health concern, significantly affecting children’s developmental trajectories, academic performance, and social functioning. These conditions, including anxiety disorders, attention-deficit/hyperactivity disorder (ADHD), oppositional defiant disorder (ODD), and mood-related disturbances, require early identification and multidisciplinary management. Pediatric nurses play a pivotal role in addressing these challenges through assessment, therapeutic interventions, family education, and psychosocial support. Their involvement spans across preventive, curative, …
Published in International Journal of Pediatric Nursing · Vol. 12, Issue 2, 2026 · pp. 23–34 Read article
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Sustainable Cementitious Composites withEpoxy–Alccofine Synergy
Abstract: This research examines the combined influence of epoxy resin and Alccofine when used as partial substitutes for cement in producing sustainable, high-performance concrete. The study aims to improve both strength and durability properties while simultaneously reducing cement usage and its environmental impact. Concrete mixes were prepared with epoxy resin contents of 0%, 5%, and 10% by weight of cement, along with Alccofine replacement levels of 5%, 10%, and 15%. The …
Published in International Journal of Concrete Technology · Vol. 12, Issue 2, 2026 · pp. 1–12 Read article
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Evaluation of Culvert design by FRP Rebars
Abstract: Abstract The increasing need for long-lasting and sustainable infrastructure has encouraged the use of innovative materials in civil engineering applications. This study examines the design of a culvert reinforced with Fiber Reinforced Polymer (FRP) bars as a substitute for conventional steel reinforcement. FRP bars provide notable benefits such as excellent resistance to corrosion, a high strength-to-weight ratio, and improved durability. These properties make them especially appropriate for structures exposed to …
Published in International Journal of Construction Engineering and Planning · Vol. 12, Issue 1, 2026 · pp. 30–35 Read article
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Establishment of a Sensitive LC-MS Method for Pharmacokinetic Evaluation of Decitabine and Cedazuridie in Rat Plasma
Abstract: Abstract A simple, rapid, and highly sensitive liquid chromatography–mass spectrometry (LC–MS) method was successfully developed and validated for the simultaneous determination of Decitabine and Cedazuridine in plasma matrices. The method demonstrated excellent linearity across the selected calibration range, with correlation coefficients (R²) consistently exceeding 0.999 for both analytes, indicating strong analytical performance. Method validation was carried out in accordance with ICH Q2(R2) and US FDA bioanalytical method validation guidelines, ensuring …
Published in International Journal of Green Chemistry · Vol. 12, Issue 1, 2026 · pp. 34–42 Read article
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Establishment of a Sensitive LC-MS Method for Pharmacokinetic Evaluation of Decitabine and Cedazuridie in Rat Plasma
Abstract: A simple, rapid, and highly sensitive liquid chromatography–mass spectrometry (LC–MS) method was successfully developed and validated for the simultaneous determination of Decitabine and Cedazuridine in plasma matrices. The method demonstrated excellent linearity across the selected calibration range, with correlation coefficients (R²) consistently exceeding 0.999 for both analytes, indicating strong analytical performance. Method validation was carried out in accordance with ICH Q2(R2) and US FDA bioanalytical method validation guidelines, ensuring compliance …
Published in International Journal of Green Chemistry · Vol. 12, Issue 1, 2026 · pp. 34–42 Read article
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A Comprehensive Review of Classical Thermodynamics:Principles, Laws, and Applications
Abstract: Classical thermodynamics, a fundamental branch of physics and engineering, provides a macroscopicframework for understanding energy, work, and heat interactions in physical systems. This reviewcomprehensively examines the principles, laws, and practical applications of classicalthermodynamics, emphasizing its enduring relevance in modern science and engineering. Beginningwith the foundational concepts of system, surroundings, state, and equilibrium, the study explores theformulation and significance of the four laws of thermodynamics. The Zeroth Law establishes the basisfor …
Published in International journal of Thermodynamics and Chemical Kinetics · Vol. 12, Issue 1, 2026 · pp. 19–26 Read article
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Smart Hospital Bed System for the Prevention and Management of Bedsores and Pressure Ulcers
Abstract: Pressure ulcers, also known as bed sores, represent a critical challenge in modern healthcare, particularly among immobilized and critically ill patients, leading to increased morbidity, prolonged hospital stays, and higher healthcare costs. Recent advancements in smart healthcare technologies have enabled the development of smart hospital bed systems that integrate sensors, automation, and artificial intelligence to prevent and manage pressure ulcers effectively. These systems incorporate features such as pressure redistribution, automatic …
Published in International Journal of Nursing Critical Care · Vol. 12, Issue 1, 2026 · pp. 1–8 Read article
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SMART SAFETY DRIVER DEVICE
Abstract: Road accidents caused by driver drowsiness, alcohol consumption, and vehicle fire hazardsremain a major concern in transportation safety. This paper presents a Smart Safety DriverDevice designed to enhance vehicle safety through real-time monitoring and automated alertmechanisms. The system integrates an eye blink sensor to detect driver fatigue, an alcoholsensor to identify alcohol presence, and a flame sensor for early fire detection. An Arduino-based controller continuously processes sensor data and activates …
Published in International Journal of Embedded Systems and Emerging Technologies · Vol. 12, Issue 1, 2026 Read article
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AI-Enabled IV Infusion Monitoring Device for Real-Time Nursing Care Optimization
Abstract: Intravenous (IV) infusion therapy is an essential component of modern healthcare, widely used for administering fluids, medications, and nutrients in clinical settings. However, traditional infusion monitoring methods rely heavily on manual observation by nursing staff, which increases the risk of human error, delayed interventions, and excessive workload. The integration of Artificial Intelligence (AI) into IV infusion systems has introduced a transformative approach to real-time monitoring, predictive analytics, and automated alert …
Published in International Journal of Nursing Critical Care · Vol. 12, Issue 1, 2026 · pp. 10–18 Read article
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Engineering Behaviour of Expansive Clay Modified with Lime, Cement, and Fly Ash for Geotechnical Applications
Abstract: Abstract Soils exhibiting high swelling and shrinkage characteristics present a persistent challenge in geotechnical engineering, particularly in regions dominated by clay-rich deposits. These materials undergo significant volumetric changes due to moisture fluctuations, often resulting in structural distress, pavement failure, and increased maintenance demands. The present study investigates the modification of expansive soil behavior through the application of chemical stabilization techniques using lime, cement, and fly ash. A structured experimental program …
Published in International Journal of Geological and Geotechnical Engineering · Vol. 12, Issue 1, 2026 Read article
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Triple Slot Patch Antenna Employing Electromagnetic Band Gap Structures
Abstract: A triple-slot patch antenna integrated with Electromagnetic Band Gap (Mushroom Electromagnetic Band Gap, Electrical Electromagnetic Band Gap) structures is designed to enhance wireless communication performance for IoT applications. It combines a compact triple-slot patch design with periodic EBG unit cells that suppress surface waves and improve gain and directivity. The antenna design is simulated at 5.5 GHz using ANSYS Electronic Desktop to evaluate its overall performance. ANSYS Electronic Desktop is …
Published in International Journal of Microwave Engineering and Technology · Vol. 12, Issue 1, 2026 · pp. 40–52 Read article
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Mitigation Measures and Disaster Preparedness: Kapkese Landslides in Kokwet Sub-Location, Kericho County, Kenya
Abstract: Abstract: The Kapkese landslide disaster struck again in December 2015, precipitated by intense, prolonged heavy rainfall from El Niño rainstorms that devastated much of Kenya. Located in the remote Kokwet Location within Kipkelion West Constituency, Kenya, this rural village has endured recurrent geohazards, most notably a deadly May 2003 event that buried a homestead, resulting in the tragic loss of a mother and her three young daughters. These incidents have …
Published in International Journal of Geological and Geotechnical Engineering · Vol. 12, Issue 1, 2026 Read article
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Total Petroleum Hydrocarbon Degradation with the Action of Bio-stimulant using NPK Fertilizer
Abstract: The total petroleum hydrocarbon degradation with the action of bio-stimulant using NPK fertilizer was monitored with respect to different concentration of dosages. The nature of the curve in relationship to the establishment of the equation of the line as well as the square root of the best of each line or curve was considered. The application of this concept enhanced the determination of the kinetic values of each bioreactor process, …
Published in International Journal of Green Chemistry · Vol. 12, Issue 1, 2026 · pp. 26–33 Read article
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A Machine Learning-Based Framework for Urban Traffic Congestion Prediction and Control Using Intelligent Transportation Systems
Abstract: Abstract Traffic congestion remains a critical challenge in rapidly expanding urban areas, causing increased travel delays, excessive fuel consumption, environmental degradation, and economic inefficiencies. Traditional traffic management approaches are often insufficient, as they lack the ability to respond dynamically to continuously changing traffic conditions. This study proposes a novel data-driven framework for the prediction and management of traffic congestion using Intelligent Transportation Systems (ITS). The methodology integrates real-time and historical …
Published in International Journal of Transportation Engineering and Traffic System · Vol. 12, Issue 1, 2026 Read article
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A Machine Learning-Based Framework for Urban Traffic Congestion Prediction and Control Using Intelligent Transportation Systems
Abstract: Abstract Traffic congestion remains a critical challenge in rapidly expanding urban areas, causing increased travel delays, excessive fuel consumption, environmental degradation, and economic inefficiencies. Traditional traffic management approaches are often insufficient, as they lack the ability to respond dynamically to continuously changing traffic conditions. This study proposes a novel data-driven framework for the prediction and management of traffic congestion using Intelligent Transportation Systems (ITS). The methodology integrates real-time and historical …
Published in International Journal of Transportation Engineering and Traffic System · Vol. 12, Issue 1, 2026 · pp. 12–17 Read article
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A Study on Knowledge of Heart Smart Diet Before and After Administration of Information Guide Sheet Among Hypertensive Clients in Selected Urban Area of Sangareddy District
Abstract: A heart-smart diet plan is a physician-recommended diet plan for hypertensive patients which includes high-fiber foods, lean proteins, low-fat and fat-free dairy products, and heart-healthy fats. It discourages the intake of saturated fat, sodium, and foods high in sugar. The present study was conducted on “a study on knowledge of heart-smart diet before and after administration of information guide sheet among hypertensive clients in selected urban areas.” Modified Pender’s health …
Published in International Journal of Cardiovascular Nursing · Vol. 12, Issue 1, 2026 · pp. 6–26 Read article
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Classification of Fetal ECG Arrhythmia by Using Advance Hybrid Deep Learning Technique CNN-LSTM
Abstract: Fetal heart abnormalities, particularly fetal heart arrhythmias, are becoming an increasing concern in maternal healthcare. Early and accurate detection remains challenging due to limitations in conventional diagnostic techniques and inadequate signal processing methods. Existing studies have applied various machine learning and deep learning approaches; however, capturing the complex characteristics of fetal electrocardiogram (ECG) signals remains a significant gap. This study proposes an advanced deep learning-based approach for detecting fetal heart …
Published in International Journal of Cardiovascular Nursing · Vol. 12, Issue 1, 2026 · pp. 27–36 Read article