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97 articles for “biological activity”
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One-Pot Multicomponent Reactions: A Versatile Approach for Heterocyclic Compound Synthesis
Abstract: Multicomponent reactions (MCRs) represent an efficient and versatile approach in organic synthesis, enabling the formation of complex molecules through a single, one-pot procedure. This methodology is particularly advantageous for the synthesis of heterocyclic compounds that are prevalent in numerous biologically active molecules and pharmaceuticals. The one-pot nature of MCRs allows for the simultaneous combination of three or more reactants, leading to high atom economy, reduced reaction times, and minimized purification …
Published in International Journal of Chemical Synthesis and Chemical Reactions · Vol. 10, Issue 1, 2025 · pp. 1–7 Read article
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Synthesis and Biological Evaluation of a Novel Schiff Base Ligand [(E)-2,4-Dichloro-6-(1-((4-Fluorophenyl) iminoethyl)phenol] and Its Metal Complexes
Abstract: The study involved the synthesis and characterization of a novel bidentate Schiff base ligand, [(E)-2,4-dichloro-6-(1-((4-fluorophenyl) iminoethyl) phenol)], derived from 1-(3,5-dichloro-2-hydroxyphenyl) ethanone and 4-fluoroaniline. Transition metal salts (Co (II), Cu (II), Fe (II), Zn (II), Ni (II), Mn (II), Ag (II), Cd (II), Hg (II), and Pd (II)) were used to synthesize metal complexes. The chemicals used were of analytical grade, and solvents were distilled before use. Characterization involved UV, IR, …
Published in International Journal of Analytical and Applied Chemistry · Vol. 10, Issue 1, 2024 · pp. 26–35 Read article
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Heterocyclic Oxadiazole Derivatives Through Various Spectroscopic Techniques as UV, IR.
Abstract: The study focuses on the synthesis, characterization, and analysis of heterocyclic oxadiazole derivatives using various spectroscopic techniques, including UV-visible (UV-Vis) spectroscopy and infrared (IR) spectroscopy. Oxadiazoles are a type of five-membered heterocyclic compounds with nitrogen and oxygen atoms. They are important in medical chemistry and materials research and show a wide range of biological activity. The synthesized oxadiazole derivatives were characterized through UV-Vis spectroscopy to investigate their electronic transitions and …
Published in International Journal of Analytical and Applied Chemistry · Vol. 10, Issue 1, 2024 · pp. 1–8 Read article
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Basics of anti-erosion protection of cultivated soils of mountain and Foothill areas of Azerbaijan
Abstract: Abstract : The article deals with the problem of protection of soil from erosion soil erosion Problems. There is an urgent task of national importance, a decision that deepens year by year. Admittedly, it is associated with both the knowledge of the outstanding role of the soil in the life of the biosphere, and recognizing that allowing 43.3% of the whole territory of Azerbaijan have experienced any type of erosion. …
Published in International Journal of Agrochemistry · Vol. 4, Issue 1, 2018 · pp. 15–22 Read article
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Quantification of Chemical Components and Phytochemical Screening of GaliumVerum by HPLC and LC-MS Analysis
Abstract: Galium verum L. – yellow "Lady's bedstraw" – contains polyphenols, flavonoids, phenyl- propanoids compounds, and iridoids in its golden yellow blossoms. The chemical makeup of the volatile fraction of Galiumverum L. was analysed.This plant is from the natural flora of Moldova (RediuIasi region, Romania) as a source of polyphenols and flavonoids.The purpose of this investigation is to investigate the composition of the herb methanol extract of Lady's bedstraw (Galium verum …
Published in International Journal of Agrochemistry · Vol. 9, Issue 1, 2023 · pp. 1–7 Read article
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Creating Awareness on Toxic Nature of Mercury
Abstract: In our day to day life, we come across in contact with hundreds of substances such as natural or synthetic which are toxic. A dangerous heavy metal that is widely present in nature is mercury. Most frequently affected by mercury toxicity includes systems like neurologic, renal organ system, and gastrointestinal system. Ingestion, injection or inhalation of any type of mercury, including skin absorption of mercury can all result in poisoning …
Published in International Journal of Green Chemistry · Vol. 8, Issue 2, 2022 · pp. 34–38 Read article
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Brief Introduction to Medicinal Chemistry
Abstract: Medicinal chemistry is an interdisciplinary scientific field of chemistry which combines the applied and basic sciences. In simple words, medicinal chemistry is an interwoven science that combines the basics of chemistry, pharmacy, and drug discovery and designing. It comprises the discovery, development, identification, and interpretation of the mode of action of biologically active molecules and compounds at molecular level.
Published in International Journal of Analytical and Applied Chemistry · Vol. 2, Issue 2, 2016 · pp. 38–39 Read article
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Use of electrolytic hydrogen bubbles for the concentration of unicellular algae
Abstract: The most of the existing unicellular algae are used for the creation of oxygen in the locked ecosystems. The concentrate of unicellular algae contains not only living cells, but also complete spectrum of the water-soluble metabolites of unicellular algae that are contained in the cultural medium. The concentrate of unicellular algae can be easily included in any existing systems of watering and feeding of animals, and also with the production …
Published in International Journal of Analytical and Applied Chemistry · Vol. 4, Issue 1, 2018 · pp. 42–49 Read article
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PARABENS AS FUTURE POTENTIAL DRUG
Abstract: Parabens are class of chemicals widely used as preservatives in the cosmetic and pharmaceutical industries. They are effective preservatives in many types of formulas. These compounds and their salts are used primarily for their bacterial and fungicidal properties. They are also used as food additives. Their analogues viz. ethers and hybrid / fused molecules also possess various biological activities which prompted us to synthesize few more analogues for their future …
Published in International Journal of Chemical Synthesis and Chemical Reactions · Vol. 4, Issue 1, 2018 · pp. 21–33 Read article
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Review on Chalcone (Preparation ,Reactions, Medical and Bio Applications)
Abstract: This survey provides information on( methods of synthesis , reactions , applications in the medical and biological activities , its uses and its source as (whether natural or synthetic) . Chalcones are chemical compounds or natural molecules have a broad spectrum of bio- activities, which are of great interest in many fields. The chemistry of chalcones appeared information about its preparation methods as a starting material in many reactions like …
Published in International Journal of Chemical Synthesis and Chemical Reactions · Vol. 5, Issue 1, 2019 · pp. 16–27 Read article
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Synthesis of Different types of Heterocycles are used by Claisen rearrangement reaction
Abstract: The Claisen rearrangement is a powerful tool for carbon-carbon bond-forming reaction which was discovered by Rainer Ludwig Claisen. The discovery of the Claisen rearrangement nearly a century ago accessible a potentially useful synthetic tool to the organic chemist. Utility of this rearrangement over the decades has been realized and the reaction has drawn the consideration of numerous research groups, which has been showed in the number of publication on the …
Published in International Journal of Chemical Synthesis and Chemical Reactions · Vol. 6, Issue 1, 2020 · pp. 44–48 Read article
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SYNTHESIS AND IR-SPECTROSCOPIC STUDY OF MIXED LIGAND COMPLEX COMPOUNDS OF COPPER (II) FORMAT WITH SOME AMIDES
Abstract: Complex compounds of metals with amides, having biological activity are widely used in agriculture. Complex compounds of copper with organic ligands are physiologically active, participating in the vital processes of living organisms; the formiats have bactericidal and fungicidal properties. For the first time, mixed ligand complex compounds of copper (II) formate with formamide, thiocarbamide, acetamide and carbamide in an aqueous solution were synthesized. Using the methods of IR spectroscopy and …
Published in International Journal of Chemical Synthesis and Chemical Reactions · Vol. 6, Issue 2, 2020 · pp. 31–38 Read article
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Advance in the Synthesis of Oxadiazole Based Heterocyclic Compound
Abstract: The five members of the heterocyclic ring 1,3,4-oxadiazole are necessary for the production of strong bioactive molecules. Numerous pharmacological effects, including anti-inflammatory, antibacterial, anticancer, antitubercular, anticonvulsant, anti-HIV, hypoglycemic, and antioxidant qualities, are exhibited by this intriguing class of chemicals. We have created four novel 1,3,4-oxadiazole compounds in the continuing study, which are sourced from the NSAID Ibuprofen. Melting point analysis and TLC were used to verify the compounds' purity. Open …
Published in International Journal of Chemical Synthesis and Chemical Reactions · Vol. 9, Issue 2, 2023 · pp. 10–15 Read article
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Nanotechnology Based Drug Delivery System in Tuberculosis: Review
Abstract: From near the beginning centuries to present life Tuberculosis remains the world-wide disease without any limitations. In the other hand, in some cases in the infected individuals the disease remains in a dormant state. In this stage the treatment is hard as the lipid mycobacterial wall is thick & the delivery of drug inside the bacterial cell is difficult. Due to this new face of TB it becomes the major …
Published in International journal of Nanobiotechnology · Vol. 3, Issue 2, 2017 · pp. 14–24 Read article
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Assessment of Polymer Nanocomposite for Packaging Uses and Concerns about Environmental and Health Effects
Abstract: A nanocomposite material is composed of several phases with at least one, two, or three dimensions in the nanoscale range. When material dimensions are lowered to the nanoscale, phase interfaces are created, and they are essential for enhancing the material's characteristics. The surface area to volume ratio of the reinforced material used to create nanocomposites has a direct bearing on how structure and property relate to one another. Due to …
Published in International Journal of Composite and Constituent Materials · Vol. 9, Issue 2, 2023 · pp. 10–36 Read article
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Effect of Bacillus Subtilis on Corrosion of Steel in Reinforced Cement Concrete
Abstract: Abstract Concrete is one of the most used building materials due to its cost- effectiveness, ease of availability, and versatility. It is the backbone of modern construction, being widely applied in infrastructure, residential, and commercial projects. However, it is particularly vulnerable to crack formation, which significantly reduces its service life. These cracks compromise structural integrity by allowing water ingress, which leads to the corrosion of reinforcing steel, eventually making the …
Published in International Journal of Concrete Technology · Vol. 11, Issue 1, 2025 · pp. 6–14 Read article
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TO INCREASE THE EFFICIENCY OF INDOOR PLANTS TO REMOVE VOC'S/HCHO IN INDOOR ENVIRONMENT
Abstract: Indoor Air Pollution is the term used to describe the number of contaminants in the air inside a building from sources such as cigarette smoking, fuel combustion for heating or cooking, certain wallboards, carpets, or insulation as well as the geology of the area (radon in soil or rocks beneath the structure).With the onset of the energy crisis, changes in the building's design owing to energy-efficient strategy, a confined space …
Published in International Journal of Plant Biotechnology · Vol. 9, Issue 1, 2023 · pp. 95–109 Read article
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Synthesis, Spectral Study, SEM Analysis and Antibacterial Study of New Indole Azo Ligand and Complexes
Abstract: Azo ligands have developed significantly in recent decades due to their fundamental role in the coordination chemistry of transition elements. Their rapid response to coordination bonding in ligand and complex chemistry, particularly with divalent ions, is a key factor. The azo-bridged bond has played a well-established role in the formation of cobalt, nickel, and copper complexes. In this study, we prepared a novel ligand, an indole derivative bonded to an …
Published in International Journal of Chemical Synthesis and Chemical Reactions · Vol. 12, Issue 1, 2026 · pp. 1–10 Read article
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Recent Advances in Fused Heterocyclic Pyridine Compounds for Bioactive Anti-Inflammatory Drug Discovery
Abstract: Heterocyclic compounds, particularly those fused with pyridine rings, have emerged as promising candidates in the search for novel bioactive agents with anti-inflammatory properties. This review highlights recent advances in the discovery and development of fused heterocyclic pyridine compounds as potential anti-inflammatory drugs. The unique structural properties of fused heterocycles contribute to their ability to modulate key inflammatory pathways. By targeting specific molecular targets involved in inflammation, such as cytokines, enzymes, …
Published in International Journal of Chemical Separation Technology · Vol. 10, Issue 1, 2024 · pp. 1–7 Read article
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A Comprehensive Study of ZnxFe2–xO3 Nanocomposite for the Applications of Medical, Photocatalytic, and Solar Cells
Abstract: ZnxFe2–xO3 nanoparticles and composites are a focus area of research in nanotechnology, biotechnology, and material engineering. The functional properties of these nanomaterials depend on the scientific method of synthesizing and characterizing procedure. In this study, greater attention is invested on biological synthesis of ZnxFe2–xO3 nanoparticles and nanocomposite. For in vivo or in vitro study, properties, such as biocompatibility, reactivity, bio sensitivity, photosensitivity, and biodegradability are considered. Besides, the Ferrofluid and …
Published in International Journal of Composite and Constituent Materials · Vol. 10, Issue 2, 2024 · pp. 44–51 Read article