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713 articles for “specificity”
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Advancement of Poly-(ADP – Ribose) Polymerase (PARP) Inhibitors in Cancer Progression and Treatment
Abstract: DNA repair mechanisms are the most common and potential targets in cancer treatment. PARP enzymes play a crucial role in detection of DNA damage and its repair and also in apoptosis. Detailed knowledge of these mechanisms leads to the development of poly-(ADP-Ribose) polymerase (PARP) inhibitors as vigorous anticancer drugs with specific action. PARP inhibitors can selectivity kill tumours with deficiencies in DNA repair proteins like BRCA1/2, exploiting synthetic lethality concept. …
Published in International Journal of Animal Biotechnology and Applications · Vol. 1, Issue 1, 2015 Read article
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Cost-Effective Procedure of Agarose Gel Recycling
Abstract: Agarose gel electrophoresis is a commonly used technique in various areas of biotechnology. This pretentious but specific analytical procedure is used in research, biomedical, and forensic laboratories. Agarose gel recycling is a realistic approach for molecular genetic studies. Reuse of agarose gel for daily routine experiments to save money due to limited financial resources for research. This practice satisfies a need to control expenses. Recycled agarose can be used for …
Published in International Journal of Animal Biotechnology and Applications · Vol. 1, Issue 2, 2015 Read article
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Gene Cloning
Abstract: Gene cloning (DNA cloning) is a technique used for the generation of precise (clones) of a specific quality or DNA sequence utilizing genetic engineering techniques. The DNA containing the target gene(s) is cut into sections utilizing restriction enzymes. These sections are then embedded into cloning vectors, for example, bacterial plasmids or bacteriophages, which exchange the recombinant DNA to reasonable host cells, for example, the bacterium E. coli. On the other …
Published in International Journal of Animal Biotechnology and Applications · Vol. 2, Issue 1, 2016 Read article
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Transgenic Animal: Their Production, Benefits and Concerned Ethical Issue
Abstract: Transgenic Animal is animals in which there has been a deliberate modification of its genome, the genetic makeup of a living being in charge of inherited characteristics. The nucleus of all cells in each living life form contains qualities made up of DNA. These qualities store data that directs how our bodies shape and capacity. Genes can be altered artificially, so that a few characteristics of an animal are changed. …
Published in International Journal of Animal Biotechnology and Applications · Vol. 2, Issue 2, 2016 · pp. 15–18 Read article
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Cryopreservation of Embryo
Abstract: Cryopreservation or cry conservation is a procedure where organelles, cells, tissues, extracellular matrix, organs or whatever other natural develops powerless to harm brought on by unregulated chemical kinetics are protected by cooling to low temperatures[1](typically - 80 °C utilizing strong carbon dioxide or - 196 °C utilizing fluid nitrogen). At sufficiently low temperatures, any enzymatic or chemical activities which may make harm the biological material being referred to be viably …
Published in International Journal of Animal Biotechnology and Applications · Vol. 2, Issue 2, 2016 · pp. 12–14 Read article
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An Overview of Stem Cells
Abstract: Immature microorganisms are a class of undifferentiated cells that can separate into specific cell types. Generally, immature microorganisms originate from two fundamental sources: • Embryos framed amid the blastocyst period of embryological advancement (embryonic immature microorganisms) and • Adult tissue (grown-up immature microorganisms). Both types are for the most part characterized by their strength, or potential to separate into various cell types, (for example, skin, muscle, bone, and so on.).
Published in International Journal of Animal Biotechnology and Applications · Vol. 2, Issue 2, 2016 · pp. 7–11 Read article
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Monosex Male Tilapia Production
Abstract: Monosex male Tilapia production prior to nutrient supplements to poor and medium class people and enhance the optimum use of the water resources and increase the GDP of nation from fisheries sector. There are most of the technique for the cultivation like Inter-specific hybridization technique, manual separation, sex reversal and non-steroidal aromatase inhibitor etc. Use of this technique, farmer can harvest the fish two times in a year and an …
Published in International Journal of Animal Biotechnology and Applications · Vol. 4, Issue 2, 2018 · pp. 18–23 Read article
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Chemotactic Behavior of Caenorhabditis elegans in Different Chemical Gradients
Abstract: The nematode Caenorhabditis elegans (C. elegans) has been extensively used as a model organism for studying various behavioral aspects in small organisms. Chemotaxis has, by far, been one of the most important studies to help us understand the fundamental search and avoid behavior of C. elegans. A typical chemotaxis assay involves the use of anesthetics to paralyze the worms near the center of a chemoattractant gradient that enables us to …
Published in International Journal of Animal Biotechnology and Applications · Vol. 5, Issue 1-2, 2019 · pp. 25–37 Read article
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Efficiency and Reliability of DNA Extraction Methods for Ixodid Ticks (Acari: Ixodidae): A Comparative Tour
Abstract: ABSTRACTIt is well understood that DNA extraction is the primary as well as the crucial step while studying ticks at molecular level. The DNA extraction methods should be straightforward, and enough efficient as well as reliable in terms of DNA quality and quantity. In the present study, two non-commercial methods named phenol chloroform isoamyl alcohol (PCI) and cetyl-trimethyl ammonium bromide (CTAB) and one commercial DNeasy tissue kit were compared based …
Published in International Journal of Animal Biotechnology and Applications · Vol. 5, Issue 1-2, 2019 · pp. 1–9 Read article
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An Evaluation of Lactate Dehydrogenase in the Lindane Exposed Fresh Water Fish, Channa punctatus
Abstract: The objective of this study was to investigate the changes in lactate dehydrogenase (LDH) activity and its isozyme profile in the lindane exposed fish, Channa punctatus, after 96h treatment with three subacute concentrations (0.025, 0.05, 0.1mg/l)). The results showed decreased activity of LDH in different organs of the fish; the values recorded were in following order: gills>brain>liver>muscle>heart>kidney. The maximum decrease was found in liver (22.53%) and minimum in muscle (12.74%). …
Published in International Journal of Animal Biotechnology and Applications · Vol. 7, Issue 1, 2021 · pp. 9–19 Read article
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Bioluminescence in Fishes and It’s Significance
Abstract: Living world is beautiful, Bioluminescence in fishes shows great adaptation in deep sea. Light producing organs are also called “ Luminous organs”. These organ are adaptive modifications of skin which serve to emit light in the waters, where the sunlight ceases to penetrate. It is present in deep sea fishes which occupy the region of 300-800 ft depth. It occurs in mid water and bottom dwelling deep sea fishes. Luminescent …
Published in International Journal of Animal Biotechnology and Applications · Vol. 9, Issue 2, 2023 · pp. 20–26 Read article
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Advancements in the Large-Scale Production of Monoclonal Antibodies (mAbs)
Abstract: The monoclonal antibodies (mAb) are the antibodies derived from single clone and are specific for an epitope, which are being commonly used in biomedical research, diagnosis and treatment of diseases. mAbs are formed by the B lymphocytes of the immune system in response to the antigens and can be produced at small as well as large scale. This review consists of the benefits, production procedures and advancements being made in …
Published in International Journal of Industrial Biotechnology and Biomaterials · Vol. 1, Issue 1, 2015 Read article
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High-Performance Thin-Layer Chirography Detection of Ethambutol
Abstract: Ethambutol belongs to the class of organic compounds known as 1, 2 amino alcohols. Being a medication, it is primarily used to treat tuberculosis. Its route of administration is oral. It is readily absorbed by gastrointestinal tract and 50% excreted unchanged by urine. Capacity of protein binding is 20–30%. It is antitubercular agent i.e. inhibiting the synthesis of spermidine in myobacteria also inhibits the transfer of mycolic acids into cell …
Published in International Journal of Industrial Biotechnology and Biomaterials · Vol. 4, Issue 1, 2018 · pp. 31–33 Read article
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A Review on the Toxicity and Effects of Heavy Metals on Environment and Health
Abstract: Heavy metals are those metals which have a specific density greater than 5g/〖cm〗^3. They are found naturally as well as manufactured artficially. The heavy metals have an adverse action on environment and on the human beings. This review is going to describe the effects of heavy metals on the humans and environment. The toxicity of some heavy metals that are abundant in our environment has also been described. This review …
Published in International Journal of Industrial Biotechnology and Biomaterials · Vol. 5, Issue 1, 2019 · pp. 17–28 Read article
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Review on Types of Automatic Sterilization Systems in Hospitals
Abstract: The current review deals with sterilization systems in hospitals, Sterilization is the comprehensive extermination of germs and disposal of their remains, and the process of removing or killing life manifestations of microorganisms; Surface bacteria and viruses include the surface of human skin or surgical device surfaces with medications or sterile fluids (or by radiation in the case of surgical devices). The World Health Organization has defined it as a term …
Published in International Journal of Industrial Biotechnology and Biomaterials · Vol. 6, Issue 1, 2020 · pp. 15–21 Read article
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Biodiesel production using waste cooking oil: influence of catalysts on reaction parameters
Abstract: Over a century ago, Rudolf Diesel tested the used of vegetable oil as fuel for his automotive engine, several years later, bio-based diesel obtain from trans-esterification of animal fats or vegetable oils in presence of catalyst have been used as alternative automotive fuels to safe guard the environment and avoid global warming. Cost of production process has limited the diversification and generalizes usage of biodiesel, thus exploring avenues for cost …
Published in International Journal of Industrial Biotechnology and Biomaterials · Vol. 7, Issue 1, 2021 · pp. 1–8 Read article
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Review on Preventive Instructions for Controlling Infectious Diseases
Abstract: The pathogens of infection are transmitted in health care centers in various ways and from a variety of sources such as air, water, food, insects, and rodents and possibly animals such as cats, patients themselves, medical personnel, visitors, cleaners, surfaces, tools and devices. Tools and surfaces are a major source of infection transmission, and a recent study showed that a large percentage of the phones of health sector workers showed …
Published in International Journal of Industrial Biotechnology and Biomaterials · Vol. 7, Issue 1, 2021 · pp. 22–28 Read article
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Optimization Strategies for Controlling Plant Growth
Abstract: Plant growth regulators (PGR’s) are chemicals used on a wide range of floricultural crops. These plant regulators modulate the plant growth in their own specific way. However, for achieving best results, it is important to understand the various other parameters that increases or decreases the effectiveness of PGR usage. This short review combines together the different environmental and cultural parameters that together with PGRs can affect plant growth. Keywords: drought …
Published in International Journal of Agrochemistry · Vol. 2, Issue 1, 2016 · pp. 22–24 Read article
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Comparative Study of Fatty Acid Profile of Fresh and Canned Tuna
Abstract: Marine fish provides important constituents for the human diet, such as lipid-soluble vitamins, microelements and polyunsaturated fatty acids (PUFA). Omega-3-PUFA are essential for normal human growth and development, and may play an important role in the prevention and treatment of cardiovascular and cerebrovascular diseases, hypertension, arthritis as well as other inflammatory and autoimmune disorders, and cancer. Fatty acid composition of fish depends on the species, individual, the catching season and …
Published in International Journal of Agrochemistry · Vol. 3, Issue 1, 2017 · pp. 10–13 Read article
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Chemical formulation technology for Agrochemical use and its benefits
Abstract: Since 1940’s, chemical industries have been trying to satisfy the demands of farmers and cultivars, to increase crop yield, quality and productivity. Chemical formulations have been developed to fulfill these needs. Pesticides comprises wide range of chemicals that are mixed together under specific conditions to yield a product that can be effectively applied at lower rates, and exhibit properties such as non-toxicity, non-target species, and is more environment-friendly [1]. The …
Published in International Journal of Agrochemistry · Vol. 3, Issue 1, 2017 · pp. 14–17 Read article