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58 articles for “drug targets”
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Originative Approaches in Powder Formulation for Enhanced Therapeutic Efficacy
Abstract: Powder formulation is a cornerstone in the pharmaceutical industry, playing a vital role in improving drug efficacy and ensuring optimal therapeutic outcomes. However, traditional formulation methods often face significant challenges, such as poor solubility and low bioavailability, which can limit the effectiveness of many drugs. To address these issues, innovative strategies have emerged, including amorphous solid dispersions (ASDs), nanotechnology, and advanced manufacturing techniques like spray drying and hot melt etrusion. …
Published in International journal of Nanobiotechnology · Vol. 11, Issue 1, 2025 · pp. 1–10 Read article
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Nanotechnology in Healthcare Applications: A Study
Abstract: Nanotechnology has arisen as a transformative field with vast potential in healthcare applications, promising to revolutionize diagnostics, therapeutics, and overall patient management. Nanotechnology manipulates molecules and atoms, creating materials and devices with extraordinary properties. This study aims to sightsee the various solicitations of nanotechnology in healthcare, highlighting its benefits, challenges, and prospects. Targeted Medication Delivery: Nanotechnology enables the design of sophisticated drug delivery systems, precisely tailoring dosage and release for …
Published in International journal of Nanobiotechnology · Vol. 10, Issue 2, 2024 · pp. 49–59 Read article
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Clinical Evaluation of Mycobacterium Tuberculosis Culture and Multiplex PCR for the Characterization of Multiple Drug Resistance Tuberculosis in Dehradun, Uttarakhand, India
Abstract: Multiple drug resistance (MDR) tuberculosis timely diagnose is of utmost clinical relevance and needs to be diagnose at initial stages for the proper treatment. The current study was done to detect the multiple genes for MDR tuberculosis (TB) in clinical isolates by molecular tools. 186 clinical samples were considered out and subjected for AFB smear preparation, Nested PCR (IS6110) for Mycobacterium tuberculosis complex detection and MDR TB PCR targeting rpoB, …
Published in International Journal of Animal Biotechnology and Applications · Vol. 3, Issue 2, 2017 · pp. 26–31 Read article
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Nano Surgery and Current Era of Nanomedicine
Abstract: Nanotechnology is one of the developing fields whole ways across the world. As the word proposes, nanotechnology is the innovation that deals with the molecule size of 10^-9 m. Nanomedicine is the use of nanotechnology in medication. It is safeguarding also, and improving human wellbeing. Today, nanomedicine takes advantage of synthesized nanoparticles like dendrimers, fullerenes, carbon nanotubes, and many others to target specific tissues and organs that cannot be transported …
Published in International journal of Nanobiotechnology · Vol. 8, Issue 1, 2022 · pp. 26–31 Read article
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Nanocarrier Technologies of the Lemon Essential Oils: Brief Review
Abstract: This review article delves into integrating nanoparticles with essential oils, focusing on lemon essential oil (LEO) and recent advancements in nanocarrier technologies and their biotechnological applications. It systematically outlines the methodologies for synthesizing various nanostructured systems, including liposomes, solid lipid nanoparticles (SLNs), and nanoemulsions, emphasizing their critical role in enhancing the bioactivity of LEO. Moreover, the review provides a comprehensive analysis of the advantages and limitations of each nanocarrier type, …
Published in International Journal of Environmental Chemistry · Vol. 11, Issue 1, 2025 · pp. 20–33 Read article
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Molecular Docking of Catharanthus Roseus Bioactive Compounds of Targetinging Bovine Leukaemia Virus
Abstract: Therapeutic potential of Catharanthus roseus bioactive compounds as the 4PHO protein inhibitors, a pathogenetic determinative factor of BLV. This work describes the use of computational drug discovery approaches in estimating the interactions conducted between 40 phytocompounds of Catharanthus roseus and the 4PHO protein. Our work has determined the presence of Pamoic acid and Vindolinine hydrochloride as the optimal choice here. Pharmacokinetic screening exhibited drug-like properties to both the highly absorbed …
Published in International Journal of Animal Biotechnology and Applications · Vol. 11, Issue 2, 2025 · pp. 19–31 Read article
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Virosomes: Understanding the Modern Concepts and Latest Applications
Abstract: A virosome is a cutting-edge hybrid drug delivery method that combines the benefits of viral and non-viral vectors. A virosome has been shown to transport a variety of physiologically active substances, including nucleic acids, peptides, proteins, and tiny chemical compounds, according to research. Surface changes of virosomes may be used to enable targeted medication delivery utilising virosome-based devices. There are presently a variety of virosome-based preventive and therapeutic medicines on …
Published in International Journal of Animal Biotechnology and Applications · Vol. 7, Issue 1, 2021 · pp. 20–31 Read article
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A Comparative Study of Intravenous Paracetamol and Intravenous Diclofenac for Post-operative Pain Relief
Abstract: Despite advancements reducing mortality rates, adverse effects such as pain, nausea, and vomiting remain prevalent and can hinder recovery. Pain is now considered the fifth vital sign, as defined by the International Association for the Study of Pain, and inadequate pain management can result in prolonged hospital stays, increased drug use, and delayed recovery. Effective postoperative pain control is crucial in preventing respiratory complications and facilitating early discharge and return …
Published in International Journal of Analytical and Applied Chemistry · Vol. 11, Issue 1, 2025 · pp. 50–56 Read article
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Recent Advances in Aquasomes Carrier Nanotechnology for Drug Delivery
Abstract: Aquasomes are a nanobiopharmaceutical carrier device with nanocrystalline calcium phosphate or ceramic diamond particle center and a polyhydroxyl oligomeric film covering them. Aquasomes are spherical 60–300 nm objects that are used to deliver drugs and antigens. It was an effective carrier mechanism for bioactive molecules such as peptides, proteins, hormones, antigens, and genes to particular locations because of properties such as defense and preservation of fragile biological molecules, conformational integrity, …
Published in International journal of Nanobiotechnology · Vol. 7, Issue 1, 2021 · pp. 35–44 Read article
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Advancements of Carbon Quantum Dot and their use in Biomedical
Abstract: Carbon quantum dots (CQDs) have gained significant attention in the biomedical field due to their unique physicochemical properties and potential biomedical applications. In this review, we provide a comprehensive overview of recent advancements in CQD synthesis, functionalization, and their use in biomedical applications. Firstly, we discuss various synthetic methods used to produce CQDs, including microwave-assisted synthesis, hydrothermal synthesis, and electrochemical synthesis. Next, we delve into the functionalization of CQDs, which …
Published in International Journal of Nanomaterials and Nanostructures · Vol. 8, Issue 2, 2022 · pp. 28–33 Read article
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Potential of Novel Carriers for Effective Management of Acetaminophen Induced Hepatotoxicity
Abstract: Liver is a vital organ of the human body. It plays an important role in the human body. Acetaminophen when taken in therapeutic doses, it is used in the treatment of various conditions. Hepatotoxicity is the prime factor responsible for drug withdrawal from the market. There is no doubt that hepatotoxicity requires considerable attention and that every viable measure be taken towards an efficient mechanism for hepatoprotection. The overdose of …
Published in International Journal of Applied Nanotechnology · Vol. 1, Issue 1-2, 2015 Read article
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Advancement of Poly-(ADP – Ribose) Polymerase (PARP) Inhibitors in Cancer Progression and Treatment
Abstract: DNA repair mechanisms are the most common and potential targets in cancer treatment. PARP enzymes play a crucial role in detection of DNA damage and its repair and also in apoptosis. Detailed knowledge of these mechanisms leads to the development of poly-(ADP-Ribose) polymerase (PARP) inhibitors as vigorous anticancer drugs with specific action. PARP inhibitors can selectivity kill tumours with deficiencies in DNA repair proteins like BRCA1/2, exploiting synthetic lethality concept. …
Published in International Journal of Animal Biotechnology and Applications · Vol. 1, Issue 1, 2015 Read article
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A Descriptive Study to Assess the Knowledge Level of Selected Character Defect among Adolescents in a Selected Village at Kanyakumari District
Abstract: The present study was undertaken to assess the knowledge level of selected character defect among adolescents in a selected village at Kanyakumari district. The aim of the study is to assess the knowledge regarding selected character defect among adolescents. To find out the association between knowledge regarding selected character defect and socio-demographic variables. Research approach: Quantitative research approach was used. Research design: A descriptive design was selected for this study. …
Published in International Journal of Obstetrics, Perinatal and Neonatal Nursing · Vol. 5, Issue 1, 2019 · pp. 14–19 Read article
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Future Aspects of Nanotechnology-Scope & Applications in India
Abstract: Nanotechnology - the science of the miniature and the technology of the future - is one of the most exciting and wide area of research which may lead to the greatest technological advances of the 21st century. It is a global phenomenon and an emerging field that finds its way into a myriad of industrial applications spanning across all areas of science and technology. Even though the field is popular …
Published in International journal of Nanobiotechnology · Vol. 1, Issue 1-2, 2015 · pp. 8–13 Read article
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SYNTHESIS OF NICOTINE CORE UNIT OF 2-NITRO-3-PHENYLPROPAN-1-OL FROM BAYLIS-HILLMAN ADDUCTS DERIVED FROM NITRO OLEFINS.
Abstract: The Baylis-Hillman adducts derived from nitroolefins have been conveniently transformed into 2- nitro-3-phenylpropan-1-ol via simple reaction condition. These compounds have been demonstrated for the synthesis of reduction olefin is highly biological reactive compounds. This novel nitro derivative of the BH adduct was simply treated with mole percentage of iron and acetic acid in reactive condition. Hence this novel nicotine core unit compounds were very intrusting and new opportunities for the …
Published in International Journal of Chemical Synthesis and Chemical Reactions · Vol. 7, Issue 2, 2021 · pp. 26–30 Read article
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Harnessing the Power of CRISPR in Animal Biotechnology
Abstract: CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) technology has revolutionized genetic engineering, ushering in a new era of advancements in biotechnology. Derived from the adaptive immune system of bacteria, the CRISPR-Cas9 system offers unparalleled precision and efficiency in genome editing. Its applications in animal biotechnology are extensive, encompassing livestock improvement, disease resistance, and biopharmaceutical production, as well as environmental conservation. In livestock, CRISPR has enabled the enhancement of desirable traits, …
Published in International Journal of Animal Biotechnology and Applications · Vol. 10, Issue 2, 2024 · pp. 6–10 Read article
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Possible drugs for Huntington’s disease from Capsicum annuum developed using molecular docking against Huntington protein
Abstract: Objective: To evaluate the efficacy of Capsicum annuum as a suitable plant for the treatment of Huntington’s disease using Pyrx. Huntington’s disease results in the damage of the nervous system over a period of time. For this study, we take into consideration Capsaicin, a compound obtained from the fruit of Capsicum annuum (bell pepper) responsible for giving the fruit it’s pungent odor. Studies show that Capsaicin plays a crucial role …
Published in International Journal of Animal Biotechnology and Applications · Vol. 9, Issue 2, 2023 · pp. 27–29 Read article
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A Technical Overview of Nanorobots Using Nanotechnology
Abstract: Nanorobots are tiny machines that can interact with biological structures and environment with previously unheard-of accuracy thanks to nanotechnology, the deception of matter on the atomic and molecular scale. The design, operation, and use of nanorobots in materials research, environmental remediation, and medicine are examined in this work. Nanorobots are designed to carry out tasks including targeted medicine delivery, microsurgical treatments, and pollution neutralization by combining concepts from materials engineering, …
Published in International Journal of Nanomaterials and Nanostructures · Vol. 12, Issue 1, 2026 · pp. 31–38 Read article