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7 articles for “Cryo-EM”
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Cryogenic Electron Microscopy Reveals Conformational Dynamics and Catalytic Mechanisms of Human Fatty Acid Synthase in De Novo Lipid Biosynthesis
Abstract: Fatty acid synthase (FASN) is a multifunctional homodimeric enzyme central to de novo fatty acid synthesis in mammals. Recent cryogenic electron microscopy (cryo-EM) studies have illuminated the structural basis of FASN catalysis, revealing multiple conformational states throughout the synthesis cycle. These findings show that the acyl carrier protein (ACP) domain dynamically shuttles substrates between spatially separated active sites, while the condensing and modifying regions remain structurally stable. In contrast to …
Published in International Journal of Analytical and Applied Chemistry · Vol. 12, Issue 2, 2026 · pp. 8–25 Read article
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Advances in Reproductive Biotechnology: Innovations in Artificial Insemination and IVF Techniques
Abstract: Reproductive biotechnology has transformed infertility management and animal breeding, with artificial insemination (AI) and in vitro fertilization (IVF) playing pivotal roles. Historically, these technologies have evolved from experimental concepts to essential tools in reproductive medicine and agriculture. AI, introduced in the early 20th century, became instrumental in optimizing breeding programs by allowing selective fertilization without physical mating, thus improving genetic diversity and disease control in livestock. Meanwhile, IVF, developed in …
Published in International Journal of Animal Biotechnology and Applications · Vol. 10, Issue 2, 2024 · pp. 11–15 Read article
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Thermal Dynamics and Kinetic Modelling of Cryogenic Fuels in Aerospace and IndustrialApplications
Abstract: Cryogenic fuels are critical for high-speed aerospace and industrial applications, where efficient handling, storage, and usage are paramount for performance and safety. This study explores the thermal dynamics and kinetic modeling of cryogenic fuels, focusing on liquid handling systems and propellant technologies. Utilizing computational fluid dynamics (CFD) analysis, the research evaluates the behavior of cryogenic liquids within insulated vessels under extreme temperature conditions, identifying key parameters that influence thermal stability …
Published in International journal of Thermodynamics and Chemical Kinetics · Vol. 10, Issue 2, 2024 Read article
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Impact of Cryogenic Temperatures on the Mechanical and Thermal Properties of Polymers and Composites
Abstract: The development of lightweight, high-performance materials for use in cryogenic environments is crucial for advanced applications in aerospace, energy storage, and industrial sectors. This study explores the thermodynamic and mechanical behavior of fiber-reinforced polymers and composite materials under extremely low-temperature conditions. The cryogenic performance of these materials, including their thermal stress resistance and impact properties, was assessed with a focus on polymer fragility and the durability of composites at temperatures …
Published in International journal of Thermodynamics and Chemical Kinetics · Vol. 10, Issue 1, 2024 · pp. 7–12 Read article
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Functional Rubber Particles and Their Applications- A Review
Abstract: Functional rubber powders (FRPs) are emerging as a potential class of materials derived primarily from end-of-life tires (ELTs) and other rubber scraps through mechanical, cryogenic, or de-vulcanization methods. These powders act as high-performance additives or reinforcing fillers in various engineering applications due to their low cost, improved surface properties, customizable particle sizes, and ability to undergo further chemical reactions. This review provides an overview of the production technologies, focusing on …
Published in International Journal of Chemical Separation Technology · Vol. 11, Issue 2, 2025 · pp. 8–16 Read article
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An Extensive Analysis of QC's Difficulties & Restrictions
Abstract: QC constitutes a fundamental shift in computational paradigms by exploiting quantum mechanical phenomena namely superposition, entanglement, and interference to achieve computational advantages over classical systems for specific problem domains. Despite significant theoretical progress, the realization of large-scale, fault-tolerant quantum computers remains impeded by a range of intrinsic and technological constraints. This paper offers a thorough & critical analysis of the principal challenges associated with QC, with a focus on de- …
Published in International Journal of Analog Integrated Circuits · Vol. 12, Issue 2, 2026 Read article
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Microstructure and Mechanical Behavior of Microalloyed Forging Steels
Abstract: The microalloyed (MA) forging steels have been developed over the past several decades and they are gradually employed in the high-performance applications in many structural, automotive, and numerous engineering applications. The principle of microalloying contents in the Fe–C alloy system, thereby preferably combined with different mechanical, heat treatment, and microalloying solubility control the precipitation behaviors that lead to enormous opportunities to develop a new generation of high strength low alloy …
Published in International Journal of Metallurgy and Alloys · Vol. 11, Issue 2, 2025 · pp. 1–14 Read article