Review  in Dapsone  and Sulpha Derivatives with their Applications in (Fertilizer, Agrochemical, Industrial, Biochemical) Fields 

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Volume: 12 | Issue: 1 | Year 2026 | Subscription
International Journal of Agrochemistry
Received Date: 02/23/2026
Acceptance Date: 02/27/2026
Published On: 2026-03-10
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By: Nagham Mahmood Aljamali, Noor Saad Jafar, and Thanaa Abed Alameer Helal.

1Professor, Organic Chemistry, Synthetic Chemistry Field, Department of Chemistry, Iraq.
2Assist. Lecturer, Department of Chemistry, College of Education for Girls, University of Kufa, Iraq.
3Assist. Professor, Department of Chemistry, College of Education for Girls, University of Kufa, Iraq.

Abstract

Dapsone structure exposed in the premature twentieth century, German researcher Paul Ehrlich was acquiring notions of discriminating harmfulness established fundamentally on the talent of individual rinses to destroy microorganisms. Gerhard Dumac  is subsequent secured a Nobel Prize intended for his attempts, accomplished a breakthrough in 1932 with the detection of the antiseptic ingredient Prontosil enflamed (actinodin sulfonamide). Additional enquiry of the elements complicated unfastened the technique for a sulfa structure and sulfone rehabilitation, original with the sighting of sulfanilamide, the energetic mediator of Prontosil, with Daniel Buffett besides his squad at the Pasteur Organization (1935), formerly with the detection of dapsone autonomously by Ernest Forteau in France besides Gladwin Battle trendy the United Kingdom. Sulfonamides entertainment as inexpensive decreasing of the enzyme dihydropteroate synthetase and reduce the creation of tetrahydrofolate in microbial chambers. Tetrahydrofolate is important in both human and bacterial cells as an enzyme coenzyme that provides one-carbon units for the synthesis of pyrimidines, which are essential for DNA synthesis. If DNA and pyrimidine synthesis are inhibited, the cell cannot grow and divide. The discovery of the chemical structure of sulfa drugs had a great impact on the development of pharmaceutical sciences, Photo-biochemistry, especially in the field of skin ointments used to treat skin rashes, eczema, psoriasis, and other purulent inflammatory diseases. Medicinal corporations construct (SO2) and DAP concluded accurate photo-industrial practices, confirming soaring excellence and integrity. These APIs exist then secondhand in the expression of different antibiotic effects, like pills, cases, and interruptions, which are commended by health care specialists to discuss microbial diseases. In overall, sulfonamides and DAP are regard as bio-structure sub-content that performance a fundamental responsibility in preventing bacterial poisons, supporting affected role with actual and directed antibiotic behaviors.

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How to cite this article: Nagham Mahmood Aljamali, Noor Saad Jafar, and Thanaa Abed Alameer Helal Review  in Dapsone  and Sulpha Derivatives with their Applications in (Fertilizer, Agrochemical, Industrial, Biochemical) Fields . International Journal of Agrochemistry. 2026; 12(1): -p.

How to cite this URL: Nagham Mahmood Aljamali, Noor Saad Jafar, and Thanaa Abed Alameer Helal, Review  in Dapsone  and Sulpha Derivatives with their Applications in (Fertilizer, Agrochemical, Industrial, Biochemical) Fields . International Journal of Agrochemistry. 2026; 12(1): -p. Available from:https://journalspub.com/publication/ija/article=24325

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