5 publications
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Isocoreopsin and Glycogen Phosphorylase – An in-silico Interaction Study: A New Way to Tackle Type 2 Diabetes (T2D)†By Rakshana Manikandan, M. Mala, G. Manikandan, Prakash Vaithyanathan
Abstract: The activity of glycogen phosphorylase (GP) plays a crucial role in regulating glycogen metabolism, and its excessive activity has been closely linked to the pathogenesis of metabolic disorders, such as type 2 diabetes (T2D). Therefore, targeting GP inhibition has emerged as a significant therapeutic strategy for managing this disease. Current research focuses on the discovery and development of novel small molecules capable of suppressing GP activity. Among these, flavonoids have …
Published in International Journal of Environmental Chemistry · Vol. 11, Issue 1, 2025 · pp. 76–80 Read article →
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Effect of the class of activating agent (inorganic vs. organic) on the structure of activated carbon materials from biomass †By Indra Neel Pulidindi, Prakash Vaithyanathan, Varadarajan Thirukallam Kanthadai, Viswanathan Balasubramanian
Abstract: The impact of the class of the activating agent (inorganic Vs organic) on the structure and the crystallographic parameters of the activated carbon materials (ACMs) from biomass was studied. The stems of the waste land weed native of India, namely, Calotropis gigantea were used as a representative example for the biomass based sustainable raw material. Likewise, carbonate (K 2 CO 3 ) and oxalate (Na 2 C 2 O 4 …
Published in International Journal of Chemical Synthesis and Chemical Reactions · Vol. 11, Issue 1, 2026 · pp. 27–35 Read article →
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Xanthommatin as Agonist for Plant’s Abscisic Acid Receptor PYL10: OCTOPUS SKIN PIGMENT TO HELP PLANTS STOP SWEATING - An in-Silico EvaluationBy Prakash Vaithyanathan
Abstract: As the world moves from global warming to the global boiling stage, drought conditions will lead to tremendous loss in the realm of agriculture. Abscisic acid, a plant hormone, controls many physiological and developmental processes in plants, such as how they respond to biotic and abiotic conditions. Researchers have synthesized agonists of ABA receptors to get around the problems with natural ABA. The need of the hour is to design …
Published in International Journal of Agrochemistry · Vol. 11, Issue 1, 2025 · pp. 1–11 Read article →
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First Ever Experimental Evidence of Nanoyeast Fermenting GlucoseBy Prakash Vaithyanathan
Abstract: In one of the earliest attempts, nanoyeast (Saccharomyces cerevisiae) particles were supported on an exotic and novel support[CD1] , namely, silica gel. The presence of nanoparticles of yeast with size as small as 161 nm was reported. Nanoyeast buds of very small size namely 41 nm were also observed in the HR SEM. Analogous to the nanoparticles in the chemical world, size reduction of microorganisms with commercial relevance like, yeast, …
Published in International Journal of Energetic Materials · Vol. 10, Issue 2, 2024 · pp. 1–6 Read article →
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Transparent Sodium Silicate Encapsulated Cellulose NanospheresBy Prakash Vaithyanathan
Abstract: Transparent cellulose is a research hotspot in current science. Transparent nanocellulose finds applications in energy, environment, defense, catalysis, and medicine. Sodium silicate-modified cellulose fibers were reported to be transparent. There have been various other strategies, like generating sulfate groups on nanocellulose surfaces for inducing transparency in cellulose-based materials. However, the synthesis of transparent nanospheres of cellulose with encapsu-lated sodium silicate has never been reported in the literature. Here in, for …
Published in International Journal of Agrochemistry · Vol. 10, Issue 2, 2024 · pp. 13–20 Read article →