All articles
28 articles
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Animal Biotechnology: Finding a Balance Between New Ideas and Morality
Abstract: Animal biotechnology has become a revolutionary subject that combines genetics,farming, and medicine. It offers new ways to solve global problems like food security,disease management, and drug manufacture. Scientists have used geneticengineering, cloning, transgenesis, and genome editing to make livestock moreproductive, generate animals that are immune to disease, and make useful scientificmodels. Transgenic animals are also being utilised more and more to maketherapeutic proteins and help with research on organ transplants.Animal …
Published in International Journal of Animal Biotechnology and Applications · Vol. 12, Issue 1, 2026 Read article
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Spermmediated gene transfer revisited: optimizing delivery, integration, and germline transmissionin large animal models
Abstract: Spermmediated gene transfer (SMGT) exploits the natural role of spermatozoa as DNA vectors to deliver exogenous genetic material to oocytes, potentially enabling economical production of transgenic large animals without complex embryo micromanipulation (1). Early proofofconcept studies established that mammalian sperm can bind, internalize, and protect exogenous DNA, leading to integration, expression, and germline transmission in various species, including pigs (24). Subsequent mechanistic work has challenged the traditional view of sperm …
Published in International Journal of Animal Biotechnology and Applications · Vol. 12, Issue 1, 2026 Read article
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Stem Cell and Cloning Technologies in Livestock Improvement: Advances, Applications, and Future Prospects for Sustainable Animal Production and Genetic Improvement
Abstract: Stem cell and cloning technologies have emerged as transformative tools for livestock improvement, enabling rapid genetic advancement, conservation of elite or endangered breeds, and development of animals with desirable production and health traits. Stem cells, including embryonic, adult, and induced pluripotent types, offer unparalleled potential due to their self-renewal, differentiation capacity, and versatility for genetic modification. Cloning technologies, particularly somatic cell nuclear transfer and embryo splitting, allow replication of superior …
Published in International Journal of Animal Biotechnology and Applications · Vol. 12, Issue 1, 2026 · pp. 44–53 Read article
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Animal Biotechnology: Finding a Balance Between New Ideas and Morality
Abstract: Animal biotechnology has become a revolutionary subject that combines genetics, farming, and medicine. It offers new ways to solve global problems like food security, disease management, and drug manufacturing. Scientists have used genetic engineering, cloning, transgenesis, and genome editing to make livestock more productive, generate animals that are immune to disease, and make useful scientific models. Transgenic animals are also being utilized more to make therapeutic proteins and help with …
Published in International Journal of Animal Biotechnology and Applications · Vol. 12, Issue 1, 2026 Read article
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Barriers to Advanced Reproductive Technologies in the Subsistence Dairy Farming Systems: Key Constraints andthe Way Forward
Abstract: The adoption of advanced reproductive technologies (ARTs) in subsistence dairy farming remainslimited despite their potential to enhance genetic improvement, fertility rates, and overall productivity.This study explores the key constraints hindering the integration of ARTs, including artificialinsemination, embryo transfer, and ovulation synchronization, within small-scale dairy productionsystems. Financial constraints, lack of awareness, inadequate veterinary support, and socio-culturalresistance are identified as primary barriers. Limited access to affordable credit, high costs ofreproductive inputs, and …
Published in International Journal of Animal Biotechnology and Applications · Vol. 12, Issue 1, 2026 Read article
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Barriers to Advanced Reproductive Technologies in the Subsistence Dairy Farming Systems: Key Constraints and the Way Forward
Abstract: The adoption of advanced reproductive technologies (ARTs) in subsistence dairy farming remains limited despite their potential to enhance genetic improvement, fertility rates, and overall productivity. This study explores the key constraints hindering the integration of ARTs, including artificial insemination, embryo transfer, and ovulation synchronization, within small-scale dairy production systems. Financial constraints, lack of awareness, inadequate veterinary support, and socio-cultural resistance are identified as primary barriers. Limited access to affordable credit, …
Published in International Journal of Animal Biotechnology and Applications · Vol. 12, Issue 1, 2026 Read article
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Enhancing Fertility in Dairy Cows: Integrating Nutritional, Hormonal, and Technological Approaches for Optimal Reproductive Health
Abstract: Enhancing fertility in dairy cows is crucial for improving reproductive efficiency, ensuring sustainable dairy production, and optimizing herd health. This study explores the integration of nutritional, hormonal, and technological approaches to achieve optimal reproductive outcomes. Nutritional interventions, including macro- and trace minerals, vitamins, protein supplements, and energy boosters, are critical in supporting the physiological demands of dairy cows, particularly during transition periods and lactation. Hormonal therapies such as progesterone, GnRH …
Published in International Journal of Animal Biotechnology and Applications · Vol. 12, Issue 1, 2026 Read article
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Molecular Docking of Catharanthus Roseus Bioactive Compounds of Targetinging Bovine Leukaemia Virus
Abstract: Therapeutic potential of Catharanthus roseus bioactive compounds as the 4PHO protein inhibitors, a pathogenetic determinative factor of BLV. This work describes the use of computational drug discovery approaches in estimating the interactions conducted between 40 phytocompounds of Catharanthus roseus and the 4PHO protein. Our work has determined the presence of Pamoic acid and Vindolinine hydrochloride as the optimal choice here. Pharmacokinetic screening exhibited drug-like properties to both the highly absorbed …
Published in International Journal of Animal Biotechnology and Applications · Vol. 11, Issue 2, 2025 · pp. 19–31 Read article
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African Swine Fever: The Silent Pandemic Affecting Global Swine Industry
Abstract: Background: African Swine Fever (ASF) is a highly contagious and fatal viral disease caused by the ASF virus (ASFV) of the Asfarviridae family, affecting domestic pigs and wild boars. First identified in Kenya in 1921, ASF has spread globally, severely impacting the pork industry and causing significant financial losses. The virus transmits rapidly through direct or indirect contact, with arthropod vectors, wildlife reservoirs, and contaminated animal products playing key roles …
Published in International Journal of Animal Biotechnology and Applications · Vol. 11, Issue 2, 2025 · pp. 6–18 Read article
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Slow-Release Nutrients in Ruminant Nutrition:Optimizing Efficiency for Sustainable Livestock Production
Abstract: The use of slow-release nutrients in ruminant nutrition has emerged as a promising strategy to enhance efficiency and promote sustainability in livestock production systems. Unlike conventional nutrient sources that are rapidly degraded in the rumen, slow-release formulations provide a controlled, steady release of essential nutrients, such as nitrogen, amino acids, minerals, and vitamins. This steady supply supports optimal rumen microbial activity, improves nutrient utilization, and minimizes metabolic disturbances, leading to …
Published in International Journal of Animal Biotechnology and Applications · Vol. 11, Issue 2, 2025 · pp. 51–63 Read article
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Comparison Analysis of Lumpy Skin Disease Detection System Using X-Ray Images of Animals with the Help of Deep Learning
Abstract: Lumpy Skin Disease (LSD), caused by the Capripoxvirus, is a highly contagious viral infection impacting cattle and other livestock, resulting in significant economic losses due to decreased productivity and mortality. Early detection is critical to mitigate its spread and reduce its impact on agriculture and dairy sectors. This study investigates the efficacy of deep learning methodologies for detecting LSD through X-ray images, offering a non-invasive diagnostic approach to identify internal …
Published in International Journal of Animal Biotechnology and Applications · Vol. 11, Issue 2, 2025 · pp. 1–5 Read article
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Egg Size Dynamics in Laying Hens: Implications for Physiological, Nutritional, and Managemental Interventions
Abstract: This review explores the factors influencing egg size variability in laying hens, emphasizing the intricate interplay between physiological, nutritional, and management aspects. Egg size is a crucial trait affecting both production efficiency and market value in poultry farming. The review discusses how genetic predispositions and physiological traits, such as the age of the hen and body condition, contribute to egg size. Additionally, nutritional factors, including protein content, energy levels, and …
Published in International Journal of Animal Biotechnology and Applications · Vol. 11, Issue 2, 2025 · pp. 1–19 Read article
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In-vitro Fertilization: Revolutionizing Livestock Breeding Efficiency
Abstract: In-vitro fertilization (IVF) has emerged as a transformative technology in animal breeding, particularly in the livestock industry. VF, or in vitro fertilization, is a process where an egg is fertilized by sperm outside the body, in a lab. After the egg is fertilized and begins to develop into an embryo, it is then placed into the uterus of the woman who will carry the pregnancy. This technique has significantly enhanced …
Published in International Journal of Animal Biotechnology and Applications · Vol. 11, Issue 1, 2025 · pp. 1–5 Read article
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Biotechnological Advancements in Animal Organ Transplantation and Xenotransplantation
Abstract: Biotechnological advancements in the fields of animal organ transplantation and xenotransplantation have made significant strides over the past few decades. These advancements offer promising solutions to the worldwide shortage of organs needed for transplants. Xenotransplantation – transplanting organs or tissues from animals to humans – shows great potential in tackling this problem. Recent breakthroughs in biotechnology, such as genetic engineering, immune suppression techniques, and improved organ preservation methods, have brought …
Published in International Journal of Animal Biotechnology and Applications · Vol. 11, Issue 1, 2025 · pp. 6–10 Read article
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Medical Research and Animal Experimentation: A Clash Between Ethics and Necessity
Abstract: Animal testing has played a crucial role in medical research, leading to major advancements like vaccines, treatments, and diagnostic methods. However, this remains a contentious issue due to ethical concerns regarding animal welfare, rights, and suffering. The growing awareness of animal sentience and the potential for pain and distress have intensified ethical debate, prompting efforts to refine regulatory frameworks and research practices. While principles, such as the “Three Rs” (Reduction, …
Published in International Journal of Animal Biotechnology and Applications · Vol. 11, Issue 1, 2025 · pp. 29–36 Read article
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Operational Complexities in Commercial Dairy Farms: Insights into Feeding, Nutrition, Health, and Management Practices for Sustainable Dairy Development
Abstract: Commercial dairy farming faces diverse range of challenges that impact productivity, profitability, and sustainability. Feeding and nutrition remain critical, with fluctuating feed costs, inconsistent forage quality, and the need to balance dietary formulations for optimal milk yield and animal health. Nutritional deficiencies and imbalances can predispose dairy cows to metabolic disorders, compromising overall performance and longevity. Health challenges, including mastitis, lameness, and reproductive disorders, are exacerbated by inadequate management practices …
Published in International Journal of Animal Biotechnology and Applications · Vol. 11, Issue 1, 2025 · pp. 37–50 Read article
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Integrating Trees, Shrubs, and Perennial Biomass Crops into Livestock Systems: A Pathway to Sustainable Tropical Farming Systems
Abstract: Livestock production in the tropics faces increasing challenges due to climate change, land degradation, feed shortages, and environmental concerns. Integrating trees, shrubs, and perennial biomass crops into livestock farming systems offers a sustainable approach to addressing these challenges. This study explores the potentials of agroforestry-based livestock systems in enhancing feed availability, improving animal nutrition, promoting soil health, and mitigating the environmental footprint of livestock farming. Trees and shrubs provide high-protein …
Published in International Journal of Animal Biotechnology and Applications · Vol. 11, Issue 1, 2025 · pp. 11–28 Read article
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Cell Culture Technologies in Animal Biotechnology: Innovations and Applications
Abstract: Cell culture technologies have become integral to animal biotechnology, enabling the in vitro study of cellular behaviors, disease mechanisms, and the development of therapeutic solutions. These technologies are foundational for advancements in drug discovery, gene therapy, regenerative medicine, and vaccine production. Over recent decades, innovations in culture media, bioreactor systems, and three-dimensional (3D) cell culture models have significantly enhanced the efficiency and reproducibility of cell-based research. Serum-free and chemically defined …
Published in International Journal of Animal Biotechnology and Applications · Vol. 10, Issue 2, 2024 · pp. 25–29 Read article
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Mirror to Review of Lumpy Skin Disease
Abstract: Lumpy Skin Disease (LSD) is a disorder which is affecting most of the animals and thus is spreading to nations worldwide and is becoming as an epidemic in current times and serves as a platform to turn attention towards its rising disorder. It is a carrier spread disease transmitted by different arthropods. This article provides detailed information about the LSD, LSDV, and diagnosis (not by regular blood tests but using …
Published in International Journal of Animal Biotechnology and Applications · Vol. 10, Issue 2, 2024 · pp. 16–24 Read article
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Animal Genetics: Impact of Crossbreeding on Dairy Cattle Health and Productivity and Exploring the Role of Stem Cells in Veterinary Regenerative Medicine
Abstract: The rapid growth in global demand for animal products, especially dairy, has driven the need for innovative approaches in animal breeding and veterinary care to meet these challenges. Among the most promising developments are crossbreeding strategies in dairy cattle and the application of stem cell technology in veterinary regenerative medicine. Crossbreeding in dairy cattle involves the mating of different breeds to enhance genetic diversity and improve key traits, such as …
Published in International Journal of Animal Biotechnology and Applications · Vol. 10, Issue 2, 2024 · pp. 1–5 Read article