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257 articles for “Drug”
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Future Outlook of Green Chemistry
Abstract: Chemistry brought about medical revolution till about the middle of 20th century in which drugs and antibiotics were discovered. The world’s food supply also increased immensely due to the innovation of hybrid varieties, enhanced methods of agriculture, better seeds, and use of herbicides, fertilizers, pesticides and insecticides. The quality of life on earth became much better due to the discovery of dyes, plastics, cosmetics and other materials. Soon, the ill …
Published in International Journal of Green Chemistry · Vol. 3, Issue 1, 2017 · pp. 27–32 Read article
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MULBERRY, MORUS ALBA (L): THE GLOBAL MEDICINAL HERITAGE
Abstract: Mulberry, Morus alba (L) is a fast-growing, small to medium-sized mulberry tree which grows to 10–20 m tall. It is generally a short-lived tree with a lifespan comparable to that of humans, although there are some specimens known to be over 250 years old The species is native to northern China, and is widely cultivated and naturalized elsewhere (United States, Mexico, Australia, Kyrgyzstan, Argentina, Turkey, Iran, etc.). Hypolipidemic and antioxidant …
Published in International Journal of Green Chemistry · Vol. 4, Issue 2, 2018 · pp. 37–60 Read article
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Brief Introduction to Medicinal Chemistry
Abstract: Medicinal chemistry is an interdisciplinary scientific field of chemistry which combines the applied and basic sciences. In simple words, medicinal chemistry is an interwoven science that combines the basics of chemistry, pharmacy, and drug discovery and designing. It comprises the discovery, development, identification, and interpretation of the mode of action of biologically active molecules and compounds at molecular level.
Published in International Journal of Analytical and Applied Chemistry · Vol. 2, Issue 2, 2016 · pp. 38–39 Read article
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A Sensitive Spectrophotometric Method for the Determination of Diazepam with MBTH
Abstract: A sensitive, specific spectrophotometric method for the determination of diazepam in bulk drug and formulations has been developed. The diazepam is hydrolyzed to yield 2-Methylamino-5- chlorobenzophenone which is coupled with 3-Methyl benzthiazolinone-2-hydrazone, in the presence of ceric ammonium sulphate as an oxidizing agent, to yield a blue colored solution having an absorbance maximum at 585 nm. It obeys Beer’s law in the concentration range of 0 – 4 µg / …
Published in International Journal of Analytical and Applied Chemistry · Vol. 3, Issue 2, 2017 · pp. 1–8 Read article
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Review on Preparation and Application Fields of Triazole &Tetrazole Derivatives
Abstract: This review described triazole and tetrazole (five-ring), these are heterocyclic aromatic five-ring compounds consisting of (two carbon atoms and three nitrogen atoms in triazole) while (four nitrogen atoms with one carbon atom in terazole), and they exist in three different formulas with different locations of heterogeneous atoms in the ring. These compounds were distinguished by a high efficiency towards microorganisms and microbes and have wide importance in the field of …
Published in International Journal of Analytical and Applied Chemistry · Vol. 6, Issue 1, 2020 · pp. 35–45 Read article
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Ayurveda as an alternative Medicine for SARS-CoV
Abstract: The goal of this study was to look at the clinical evidence for complementary and alternative medicine treatments for major depressive disorder. The phrase depressive disorder was combined with St John’s wort, S-adenosylmethionine (SAM-e), exercise, acupuncture, omega-3 fatty acids, and folate in a PubMed search from January 1966 to February 2010. Only relevant human trials were selected. COVID-19, the current global health emergency, is not the first-time coronaviruses have posed …
Published in International Journal of Analytical and Applied Chemistry · Vol. 7, Issue 2, 2021 · pp. 28–36 Read article
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Purification of Plasmodium Recombinant Protein
Abstract: Malaria is a protozoan disease, caused by parasite plasmodium. There are several species of plasmodium like as P. vivax, P. Ovule, P. Falciparum. It is globally spreaded disease. In 2017, there were an estimated 219 million cases of malaria in 87 countries & deaths stood at 435 000 (WHO.Which protein we purified, we only knew the sequence. So if we could know the function of the protein then we can …
Published in International Journal of Analytical and Applied Chemistry · Vol. 8, Issue 1, 2022 · pp. 7–20 Read article
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Extraction of Bioflavonoid from Peel of Citrus sinensis
Abstract: Citrus sinensis is belongs to the Rutaceae family. This is also known as orange fruit and it contains several phytochemicals like phenolic compounds, phenolic acids, bioflavonoids (quercetin, rutin and kaempferol), saponins, carotenoids, citric acid and vitamin C (ascorbic acid). It shows various pharmacological activities like antioxidant activity, anti-inflammatory activity, anti-diabetic activity, anti-cancer activity, wound healing activity etc. This plant control the various disorders in the society. Bioflavonoids also assist in …
Published in International Journal of Chemical Separation Technology · Vol. 7, Issue 1, 2021 · pp. 1–5 Read article
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Nanofiltration a chemical separation technique
Abstract: Nanofiltration innovation has made considerable progress since its first commencement in the last part of the 1980s. The essential diaries detailing articles on nanofiltration are the Journal of Membrane Science, Desalination and Separation and Purification Technology. There has been a clear development in the space of natural dissolvable nanofiltration, drug, and organic applications, plan and financial aspects of nanofiltration cycles, and survey articles.Nanofiltration (NF) with benefits of high productivity and …
Published in International Journal of Chemical Separation Technology · Vol. 7, Issue 2, 2021 · pp. 34–38 Read article
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Synthetic Studies on Fused Benzodiazepines: A Class of Medicinally Privileged Heterocycles
Abstract: 1,4-Benzodiazepine is an important nitrogen heterocyclic scaffold because of its presence in various natural products, drugs and biologically active molecules. Henceforth, it is also known as privileged heterocycle in the field of medicinal to synthetic organic chemistry. Reactions towards the synthesis of five- and six- membered heterocycles are very easy and facile. On the other hand, synthesis of medium ring heterocycles is more difficult because of the thermodynamic limitations. Thus …
Published in International Journal of Chemical Synthesis and Chemical Reactions · Vol. 4, Issue 2, 2018 · pp. 44–59 Read article
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Applications of Separation of Materials
Abstract: The main aim in our work deals with the preparation of series of new bio compounds that have interesting in bio and biomedical fields, pharmaceutical drugs, medicinal biochemistry and in other fields also. All compounds have wide applications and the prepared bio compounds were prepared through many steps with various conditions like azetidine, imidazole, thiazine, oxazepine , diazepine , tetrazole. The structure of the newly synthesized compounds were monitored by …
Published in International Journal of Chemical Synthesis and Chemical Reactions · Vol. 5, Issue 2, 2019 · pp. 20–24 Read article
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REVIEW ON PREPARATION & APPLICATIONS OF THIADIAZOLE DERIVATIVES
Abstract: This review has touched on thiadiazole derivatives as it is a basis for the synthesis of many drugs, industrial compounds, chemical dyes, pharmaceuticals and life substances, and as a link to many cyclic reactions and is produced in vitro methods for the hydrolysis of the amine-thiol compounds such as thiosemicarbazide and hydrazo-thion, among others. On the different methods of preparation for thiadiazole derivatives, its reactions and its various biological applications., …
Published in International Journal of Chemical Synthesis and Chemical Reactions · Vol. 6, Issue 1, 2020 · pp. 19–30 Read article
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REVIEW ON PREPARATION METHODS & APPLICATION FIELDS OF OXADIAZOLE
Abstract: This review displays oxadiazole (five-ring) that is of great importance in the fields of pharmacy, medicine, and field of coordinated chemistry and as reagents to estimate the small quantities of trace elements and minerals. Oxadiazole is a primary role and as a basic substance for many pharmacokinetic compounds such as antimalarial drugs, anti- bacterial, and cancerous tumors. This survey described several approach for preparation methods of oxadizole with their applications …
Published in International Journal of Chemical Synthesis and Chemical Reactions · Vol. 6, Issue 1, 2020 · pp. 49–60 Read article
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Aerogel from Ceramic Composite
Abstract: This article is written from conferred articulated forms of aerogel. Sol-gel is a usual method toprepare aerogel. Compromise of inherent fragile mater under extensive moisture absorption tendencyof silica network has mitigated after inclusive of polyhedral oligomeric silsesquioxane (POSS)molecule. Long term applicability of silica aerogel has cited to confer superhydrophobic and flexibleconfigure based on synthesis by the catalysed sol-gel process; in accord of usual two-step method ofacid activation followed by basic …
Published in International Journal of Chemical Synthesis and Chemical Reactions · Vol. 7, Issue 1, 2021 · pp. 1–12 Read article
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SYNTHESIS OF NICOTINE CORE UNIT OF 2-NITRO-3-PHENYLPROPAN-1-OL FROM BAYLIS-HILLMAN ADDUCTS DERIVED FROM NITRO OLEFINS.
Abstract: The Baylis-Hillman adducts derived from nitroolefins have been conveniently transformed into 2- nitro-3-phenylpropan-1-ol via simple reaction condition. These compounds have been demonstrated for the synthesis of reduction olefin is highly biological reactive compounds. This novel nitro derivative of the BH adduct was simply treated with mole percentage of iron and acetic acid in reactive condition. Hence this novel nicotine core unit compounds were very intrusting and new opportunities for the …
Published in International Journal of Chemical Synthesis and Chemical Reactions · Vol. 7, Issue 2, 2021 · pp. 26–30 Read article
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Exploring Thermodynamic Heterocyclic Compounds: A Comprehensive Analysis
Abstract: Heterocyclic compounds constitute a significant class of organic molecules with diverse applications in various fields including pharmaceuticals, materials science, and agrochemicals. Understanding their thermodynamic properties is crucial for elucidating their behavior in different environments and optimizing their applications. This comprehensive analysis delves into the thermodynamic aspects of heterocyclic compounds, encompassing their synthesis, structural characteristics, and energetics. The review begins by outlining the fundamental principles governing the thermodynamics of heterocyclic compounds, …
Published in International journal of Thermodynamics and Chemical Kinetics · Vol. 9, Issue 1, 2023 · pp. 40–46 Read article
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A Realtime Coronavirus Notifier
Abstract: Fresh corona virus deadly disease has not clinically confirmed vaccine or medicines. Its tolerant are improving through the help of antibiotic drug, anti-viral treatments, over and above vitamin C supplementation. It is currently apparent that the world necessities an expedient and speedier answer for contain and tackle the further spread of COVID-19 across the world with the guide of non-clinical advance for instance data mining schemes, improved aptitude furthermore extra …
Published in International Journal of Distributed Computing and Technology · Vol. 7, Issue 1, 2021 · pp. 22–25 Read article
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Synthesis of Zinc Oxide Nanoparticles by Simple Hydrothermal Process
Abstract: Rapid synthesis of zinc oxide nanoparticles through economically feasible hydrothermal approach is highly desirable. In this study, we have developed a method to synthesize zinc oxide nanoparticles by using simple hydrothermal process in aqueous zinc salt solution (ZnCl2) without need of any surfactant or external energy. This experimentation produced physiologically stable, bio-compatible ZnONPs which may be used for targeted drug delivery that offers enhanced therapeutic efficacy and minimal side effects. …
Published in International Journal of Applied Nanotechnology · Vol. 2, Issue 1, 2016 · pp. 8–16 Read article
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Potential of Novel Carriers for Effective Management of Acetaminophen Induced Hepatotoxicity
Abstract: Liver is a vital organ of the human body. It plays an important role in the human body. Acetaminophen when taken in therapeutic doses, it is used in the treatment of various conditions. Hepatotoxicity is the prime factor responsible for drug withdrawal from the market. There is no doubt that hepatotoxicity requires considerable attention and that every viable measure be taken towards an efficient mechanism for hepatoprotection. The overdose of …
Published in International Journal of Applied Nanotechnology · Vol. 1, Issue 1-2, 2015 Read article
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Porous Silicon and its Nanoparticles: A Theoretical Study
Abstract: It is very simple and cost consuming technique of fabrication of porous silicon film over silicon substrate and synthesizing the porous silicon and silicon nanoparticles. The etch reactions in RIVPSE process forms the porous structures without need of complex and expensive equipments. The luminescent porous film can be fabricated using this sample technique with any cost effecting methods such as extra energy excitation like plasma or ultraviolet photon and additional …
Published in International Journal of Applied Nanotechnology · Vol. 5, Issue 1, 2019 · pp. 14–18 Read article