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30 articles for “bioavailability”
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Studies on Extraction, Modelling and Purification of Quercetin from Peel of Allium cepa
Abstract: ABSTRACT Quercetin is an anti-oxidant, which very efficiently scavenges highly reactive biological species such as peroxynitrite and hydroxyl radical. Quercetin belongs to the flavonoid’s family. The present studies on optimization of physico-chemical parameters like effects of different solvents, different solvent percentages, particle size, pH and extraction time for the extraction of quercetin was studied. The highest quercetin concentration for optimized conditions was 38 µg/ml. In the soxhlet extraction process, the …
Published in International Journal of Plant Biotechnology · Vol. 4, Issue 1, 2018 · pp. 3–11 Read article
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Sourdough in Bread-Making: An Ancient Technology to Solve Modern Issues
Abstract: The production of sourdough can be traced back to ancient times. It is a mixture of flour and water, fermented with lactic acid bacteria. Use of sourdough to improve texture and palatability of cereal products is gaining importance. In addition to providing structure, texture and aroma to rye and wheat breads, sourdough also improves the nutritional quality and provides health benefits. It can retard starch digestibility leading to lower glycemic …
Published in International Journal of Industrial Biotechnology and Biomaterials · Vol. 1, Issue 1, 2015 Read article
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Phosphate Solubilizing Microbes: Sustainable Approach for Managing Phosphorus Deficiency in Agricultural Soils
Abstract: As compared to many other major nutrients, phosphorus is by far the least mobile and accessible to plants in almost all type of soil conditions. Phosphorus occurs in abundant quantity in soils in both organic and inorganic forms; still it is frequently a prime limiting factor for plant growth. The bioavailability of inorganic phosphorus in the soil rhizosphere varies with factors that include: type of plant species, nutritional status of …
Published in International Journal of Agrochemistry · Vol. 2, Issue 1, 2016 · pp. 1–8 Read article
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Solubility Enhancement of Theophylline Drug Using Mixed Solvency Approach
Abstract: “Solubility enhancement” is one of the difficult tasks that have become a great challenge in formulation development of orally administered drugs having poor aqueous solubility. Poor aqueous solubility of drugs creates significant problems in producing formulations of sufficiently high bioavailability, thereby preventing the effective usage of these drugs. With the introduction of the concept of “mixed-solvency,” it is feasible to increase the solubility of poorly water-soluble drugs in aqueous solutions …
Published in International Journal of Chemical Separation Technology · Vol. 1, Issue 2, 2015 · pp. 1–4 Read article
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Schemes of Trace Selenium Nanoparticles on Earth
Abstract: This article is written about resources of selenium compatible with dosage-wise recovery from nature. Selenium (Se) above trace is toxic to human beings. The plant is the source of Se based on differential stages in botanical ethics from various parts of plants. Selenium found in nature as selenite, selenite, selenides, and seleno-proteins in plants. Se nanospheres related to a size considered as of importance in industry and biology acts. Antimicrobial …
Published in International Journal of Chemical Separation Technology · Vol. 7, Issue 1, 2021 Read article
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Potential of Novel Carriers for Effective Management of Acetaminophen Induced Hepatotoxicity
Abstract: Liver is a vital organ of the human body. It plays an important role in the human body. Acetaminophen when taken in therapeutic doses, it is used in the treatment of various conditions. Hepatotoxicity is the prime factor responsible for drug withdrawal from the market. There is no doubt that hepatotoxicity requires considerable attention and that every viable measure be taken towards an efficient mechanism for hepatoprotection. The overdose of …
Published in International Journal of Applied Nanotechnology · Vol. 1, Issue 1-2, 2015 Read article
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Formulation and Characterization of Polyhydroxyalkanoates Copolymer Nanoparticles for Controlled Drug Release
Abstract: The present study was focused on the formulation of polyhydroxyalkanoates copolymer nanoparticles (PHANPs) for in vitro controlled release of the drugs, viz. levofloxacin and amoxicillin. The PHANPs were synthesized by a triple emulsion method and conjugated with amoxicillin and levofloxacin to improve its remedial bioavailability. The PHANPs and drug conjugatedPHANPs were analysed using Scanning Electron Microscopy (SEM), Fourier Transform Infrared (FTIR) spectroscopy and X-Ray Diffraction (XRD). The cell viability % …
Published in International journal of Nanobiotechnology · Vol. 6, Issue 2, 2020 · pp. 1–11 Read article
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An Overall Review on Vesicular Drug Delivery System for Improved Skin Permeation
Abstract: The main objective of a vesicular drug delivery system is to enhance medication bioavailability in systemic circulations. The non-steroidal anti-inflammatory drugs, anti-psoriatic drugs and for the topical drugs vesicular drug delivery system is considered as most effective approach to attain local effect as well as systemic effect. The significance and applicability of vesicular drug delivery systems were examined in depth in this article.
Published in International journal of Nanobiotechnology · Vol. 7, Issue 2, 2021 · pp. 31–38 Read article
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Nanosuspension-novel Technique for Solubility Enhancement
Abstract: In the treatment of many diseases, getting medicinal compounds to the desired location is a serious issue. Poor biodistribution, limited effectiveness, unfavorable side effects, and a lack of selectivity define traditional medication use. Different types of nanostructures are produced using various size reduction processes and technologies, each with its own set of physicochemical and biological features. These technologies make nanostructures a good material for biomedical applications, and they've gained a …
Published in International Journal of Nanomaterials and Nanostructures · Vol. 7, Issue 2, 2021 · pp. 18–24 Read article
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Nanostructures: Advancing Targeted Metabolic Engineering for Treating Metabolic Disorders.
Abstract: Nanostructures have emerged as powerful tools in the field of targeted metabolic engineering,offering precise control over metabolic pathways in specific cells or tissues. This technologyholds great promise for treating a wide range of metabolic disorders by modulating cellularmetabolism at the nanoscale.One of the key advantages of nanostructures in metabolic engineering is their ability to targetspecific cells or tissues with high precision. By encapsulating or delivering metabolicmodulators such as enzymes, cofactors, …
Published in International Journal of Nanomaterials and Nanostructures · Vol. 9, Issue 2, 2023 · pp. 16–21 Read article