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257 articles for “Drug”
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A Review Paper on Novel Lipid Nanoparticles for Enhanced Bioavailability of Bioactive Compounds in Breast Cancer Cell Lines
Abstract: Most bioactive compounds from natural products are heavily relied on drug development due to their biological, chemical and pharmacological properties. Some compounds exhibiting anticancer properties have also been reported. However, they present a challenge in achieving the effective absorption and delivery in the body. This is due to minimal bioavailability, fluctuation of plasma drug concentration, low tolerance, first-pass effect which leads to less desired efficacy. Therefore, this calls for an …
Published in International Journal of Composite and Constituent Materials · Vol. 10, Issue 1, 2024 · pp. 1–9 Read article
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Clinical Evaluation of Mycobacterium Tuberculosis Culture and Multiplex PCR for the Characterization of Multiple Drug Resistance Tuberculosis in Dehradun, Uttarakhand, India
Abstract: Multiple drug resistance (MDR) tuberculosis timely diagnose is of utmost clinical relevance and needs to be diagnose at initial stages for the proper treatment. The current study was done to detect the multiple genes for MDR tuberculosis (TB) in clinical isolates by molecular tools. 186 clinical samples were considered out and subjected for AFB smear preparation, Nested PCR (IS6110) for Mycobacterium tuberculosis complex detection and MDR TB PCR targeting rpoB, …
Published in International Journal of Animal Biotechnology and Applications · Vol. 3, Issue 2, 2017 · pp. 26–31 Read article
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Development and Validation of a Reversed-Phase HPLC Method for the Simultaneous Determination of Telmisartan and Its Related Compound B (Positional Isomers) in the Bulk Drug
Abstract: A simple, selective, accurate, precise and linear RP-HPLC method was developed and validation for Simultaneous determination of Telmisartan and its related Compound B 4ʹ-[(1,7-Dimethyl-2'-propyl[2,5'-bi-1H-benzimidazol]-1'-yl)methyl][1,1'-biphenyl]-2-carboxylic acid; 4'-[(1,7'-dimethyl-2'-propyl-1H,1'H-2,5'-bibenzo[d]imidazol-1'-yl)methyl]biphenyl-2-carboxylic acid; was accomplished in the bulk drug and synthesis for drug and a tablet formulation using a Reversed Phase High Performance liquid chromatography method with UV detection separation was achieved on Inertsil ODS-3V column (150 × 4.6 mm, 5 μm) (GL Science) as stationary …
Published in International Journal of Analytical and Applied Chemistry · Vol. 1, Issue 2, 2015 · pp. 12–23 Read article
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Photon assisted Bio Nanopolymers for applications of drug delivery, diagnosis & would healing
Abstract: Biopolymers are valuable complex materials. They attract attentions of many scientists, engineers, and medical professionals’ for application research. The focus of this research is a base line assessment of valuable Nanosized biopolymers, Chitosan. As ordinary polymers, nano sized biopolymers are visualized as natural and synthetic polymers. Hence, systematic descriptions of nanosized biopolymers, the synthesis methods, characterization methods, and biomedical application will be presented. In this regard, the photon activated green …
Published in International Journal of Polymer Science and Engineering · Vol. 8, Issue 2, 2022 · pp. 25–36 Read article
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Knowledge of Staff Nurse on Selected Obstetric Drugs
Abstract: A study to assess the effectiveness of self-instructional module on selected common obstetric drugs in terms of knowledge among the staff nurses working in selected district hospitals of Gujarat state was conducted using questionnaire to collect the demographic variables and knowledge level of the staff nurse regarding the drug. Effectiveness of the self-instructional module is assessed using the same questionnaire. Sixty samples were selected for the study with non-probability convenient …
Published in International Journal of Obstetrics, Perinatal and Neonatal Nursing · Vol. 6, Issue 2, 2020 · pp. 40–45 Read article
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Emulsomes-based Formulations for Effective Delivery of Small Molecules: Recent Advances and Modern Applications Perspectives
Abstract: Oral administration is the simplest, most cost-effective, and most important form of medication delivery. As a result, scientists have faced difficulty in improving dosage formulations, particularly for the goal of extended-release. Vesicular drug delivery methods were created to address issues with medicines such as low bioavailability, protection from the hostile stomach environment, and protection against degrading gastric enzymes. Emulsomes were created as a new lipoidal vesicular system with an internal …
Published in International Journal of Industrial Biotechnology and Biomaterials · Vol. 7, Issue 1, 2021 · pp. 29–39 Read article
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Green synthesis of copper nanoparticles using methanol extract of Passiflora foetida and its drug delivery applications
Abstract: The present study outlines a green synthetic approach on copper nanoparticles by mixing the copper salt solution with a methanol extract of leaves of Passiflora foetida. The plant extract play as a reducing agent for copper ions in copper solution into copper nanoparticles providing a safer process. The plant extract contains numerous secondary metabolites involving in the reduction of copper ions into forming nanoparticles. The spectroscopic analysis of green synthesized …
Published in International Journal of Green Chemistry · Vol. 3, Issue 2, 2017 · pp. 31–52 Read article
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Refractometrically studies ofAtorvastatin drugs in various concentrationsof polar protic, aprotic and non-polar solvents at 303.150K.
Abstract: By using the refractometer to investigating the density and refractive index, molar refraction (Rm) and molar polarizability constant (a) at various concentration Atorvastatin heterocyclic drugs have been studied in ethanol, DMF and dioxane solvent at 303.150K.The magnitude of molar refraction (Rm) and molar polarizability constant (a) of Atorvastatindrug is observed to be higher in polar protic solvents like ethanol than polar aprotic solvents like DMF and non-polar solvents as like …
Published in International Journal of Analytical and Applied Chemistry · Vol. 9, Issue 2, 2023 · pp. 26–30 Read article
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Material and Energy Balances in the Process of Anti-Bacterial Drugs from Erythromycin
Abstract: Erythromycin is a crucial material for production of active pharmaceutical ingredient with several different applications to treat diseases. Demand for erythromycin derivatives has been accumulated within the last twenty years and drastically in last 2 years as a key raw material for COVID-19. Clarithromycin is one amongst the derivatives of erythromycin that has higher anti-bacterial properties. This paper involves manufacture of Clarithromycin, an anti-bacterial drug, from Erythromycin. Selective methylation of …
Published in International Journal of Chemical Engineering and Processing · Vol. 7, Issue 2, 2021 · pp. 21–36 Read article
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Nano suspensions: A Potential Approach for Drug Delivery System
Abstract: Nanotechnology is likely to revolutionize our lives, in general, and health milieu, in particular. It is emerging discipline that comprises an aggrandizing sophisticated ability to manipulate matter at the nanoscale (0.1–1000 nm) resulting in new material, product and device that demonstrate new and unusual behavior. This paper garners information regarding the intriguing feature of nanosuspension and its properties. Nanosuspension have many advantageous since it has an efficient solubility when compared …
Published in International journal of Nanobiotechnology · Vol. 4, Issue 1, 2018 · pp. 5–8 Read article
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Distribution of Drug on Bed: An Effort to Reduce the Crowd in Sawai Man Singh Hospital, Jaipur, Rajasthan (India)
Abstract: Sawai Man Singh Hospital, Jaipur, Rajasthan, one of the largest hospitals of the country, is staffed with 700 doctors and 1770 nurses with 2282 beds in 72 wards. It has many specialty and super-specialty departments with many intensive care units, semi-intensive care units and operation theatres. It is the most populated hospital of the country with 575 average patients in in-patient department, 7780 average patients in out-patient department and 854 …
Published in International journal of Nursing Science Practice and Research · Vol. 5, Issue 1, 2019 · pp. 6–11 Read article
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Biopolymers in Medical Application: A Study
Abstract: Biopolymers – naturally derived macromolecules, such as polysaccharides, proteins, and polyhydroxyalkanoates – have emerged as a versatile toolbox for next-generation medical technologies. Their intrinsic biocompatibility, tunable degradation kinetics, and capacity for molecular functionalization enable the design of devices that communicate with living tissue rather than merely coexist with it. This review synthesizes recent advances across four inter-related fronts: (i) drug-delivery carriers, where chitosan-based nanoparticles and hyaluronic-acid hydrogels provide stimulus-responsive release …
Published in International Journal of Polymer Science and Engineering · Vol. 11, Issue 2, 2025 · pp. 1–15 Read article
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A Descriptive Study To Assess The Prevalence Of Diabetes Mellitus And Hypertension And Compliance To Drug Regimens Among The Adult Population Of The Selected Rural Community, Coimbatore, Tamilnadu, India
Abstract: The present study entitled This descriptive study aimed to assess the prevalence of diabetes mellitus and hypertension, as well as medication adherence, among the adult population of a selected rural community in Coimbatore. The objectives were to determine the prevalence of diabetes and hypertension, measure medication adherence for both conditions, and explore the relationship between adherence levels and selected demographic variables. A non-experimental descriptive research design was used for the …
Published in International Journal of Cardiovascular Nursing · Vol. 11, Issue 1, 2025 Read article
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A Descriptive Study To Assess The Prevalence Of Diabetes Mellitus And Hypertension And Compliance To Drug Regimens Among The Adult Population Of The Selected Rural Community, Coimbatore, Tamilnadu, India
Abstract: The present study entitled This descriptive study aimed to assess the prevalence of diabetes mellitus and hypertension, as well as medication adherence, among the adult population of a selected rural community in Coimbatore. The objectives were to determine the prevalence of diabetes and hypertension, measure medication adherence for both conditions, and explore the relationship between adherence levels and selected demographic variables. A non-experimental descriptive research design was used for the …
Published in International Journal of Cardiovascular Nursing · Vol. 11, Issue 1, 2025 Read article
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The Role of Intravenous Drug Agents in Postoperative Analgesia: A Chemical Evaluation
Abstract: This study evaluates the efficacy of two commonly used injectable pain-relieving agents in post- operative care, aiming to optimize pain management protocols and enhance patient recovery. One hundred ASA I and II patients undergoing general and gynecological procedures were randomly divided into two groups of 50, each receiving a different analgesic treatment. Vital parameters, including heart rate, respiratory rate, oxygen saturation (SpO₂), blood pressure, sedation levels, pain scores (VAS), side …
Published in International Journal of Analytical and Applied Chemistry · Vol. 11, Issue 2, 2025 Read article
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Possible drugs for Huntington’s disease from Capsicum annuum developed using molecular docking against Huntington protein
Abstract: Objective: To evaluate the efficacy of Capsicum annuum as a suitable plant for the treatment of Huntington’s disease using Pyrx. Huntington’s disease results in the damage of the nervous system over a period of time. For this study, we take into consideration Capsaicin, a compound obtained from the fruit of Capsicum annuum (bell pepper) responsible for giving the fruit it’s pungent odor. Studies show that Capsaicin plays a crucial role …
Published in International Journal of Animal Biotechnology and Applications · Vol. 9, Issue 2, 2023 · pp. 27–29 Read article
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PARABENS AS FUTURE POTENTIAL DRUG
Abstract: Parabens are class of chemicals widely used as preservatives in the cosmetic and pharmaceutical industries. They are effective preservatives in many types of formulas. These compounds and their salts are used primarily for their bacterial and fungicidal properties. They are also used as food additives. Their analogues viz. ethers and hybrid / fused molecules also possess various biological activities which prompted us to synthesize few more analogues for their future …
Published in International Journal of Chemical Synthesis and Chemical Reactions · Vol. 4, Issue 1, 2018 · pp. 21–33 Read article
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Drugs Used for the Treatment of Heart Diseases
Abstract: The heart is the body's primary pump for the development of blood. It circulates essential blood, oxygen, and supplements all through your body. Coronary illness happens when the veins of the heart are harmed or unhealthy. Coronary illness can have numerous genuine outcomes. It can prompt to a heart attack (myocardial dead tissue), congestive heart Failure, or arrhythmias, all of which can bring about death.
Published in International Journal of Cardiovascular Nursing · Vol. 2, Issue 2, 2016 · pp. 1–3 Read article
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Immunosuppressant Drugs and Their Side Effects
Abstract: Immunosuppressive medications or immunosuppressive specialists or antirejection prescriptions are medications that restrain or avoid movement of the insusceptible framework. They are utilized as a part of immunosuppressive treatment to: Keep the dismissal of transplanted organs and tissues (e.g., bone marrow, heart, kidney, liver) Treat immune system infections or ailments that are no doubt of immune system root (e.g., rheumatoid joint inflammation, different sclerosis, myasthenia gravis, psoriasis, vitiligo, systemic lupus erythematosus, …
Published in International Journal of Nursing Critical Care · Vol. 2, Issue 2, 2016 · pp. 15–18 Read article
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Non-Drug Management of Restless Legs Syndrome or Willis–Ekbom Disease
Abstract: Restless legs syndrome (RLS) is a condition which causes an uncontrollable urge to move legs because of an uncomfortable sensation. It begins or worsens during periods of rest or inactivity, is partially or totally relieved by movements, and is exacerbated or occurs at night and in the evening. RLS sufferers represent 2%–3% of the population in the western countries. RLS, also known as Willis–Ekbom disease, can begin at any age …
Published in International journal of Nursing Science Practice and Research · Vol. 6, Issue 2, 2020 · pp. 62–66 Read article