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127 articles for “pharmaceuticals”
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Artificial Intelligence for the Art and Science of Separation: Optimizing Chemical Systems
Abstract: Chemical separation processes play a critical role across chemical manufacturing, energy production, pharmaceuticals, and environmental remediation, yet they remain among the most energy-intensive operations in modern industry. Recent advancements in artificial intelligence (AI) offer transformative opportunities to significantly improve the efficiency, selectivity, and sustainability of these systems by leveraging computational power and data-driven insight. This article reviews the emerging integration of machine learning, data-driven modeling, and advanced optimization algorithms with …
Published in International Journal of Chemical Separation Technology · Vol. 11, Issue 2, 2025 · pp. 1–7 Read article
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Investigation of the Physical and Chemical Properties of Different Species of Onion
Abstract: An investigation on the physical and chemical properties of white, red, and brown onions was carried out to assess the potential applications of the different species sampled in this study. The physical properties monitored include refractive index, viscosity, and density. For red onion, the refractive index, viscosity, and density were measured as 1.35322, 1.631 cSt, and 1.1140 g/cm³, respectively. Brown onion exhibited values of 1.3571, 3.045 cSt, and 1.1130 g/cm³, …
Published in International Journal of Chemical Synthesis and Chemical Reactions · Vol. 11, Issue 2, 2026 · pp. 1–15 Read article
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Investigation of the Physical and Chemical Properties of Different Species of Onion
Abstract: An investigation on the physical and chemical properties of white, red, and brown onions was carried out to assess the potential applications of the different species sampled in this study. The physical properties monitored include refractive index, viscosity, and density. For red onion, the refractive index, viscosity, and density were measured as 1.35322, 1.631 cSt, and 1.1140 g/cm³, respectively. Brown onion exhibited values of 1.3571, 3.045 cSt, and 1.1130 g/cm³, …
Published in International Journal of Chemical Synthesis and Chemical Reactions · Vol. 11, Issue 2, 2026 · pp. 1–15 Read article
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Aromaticity-Guided Synthesis and Reactivity of Heterocyclic Compounds: Structural Insights and Applications
Abstract: The concept of aromaticity serves as a fundamental framework for understanding the structural and electronic characteristics of heterocyclic compounds, which play a crucial role in modern synthetic chemistry. Aromatic compounds, characterized by cyclic planar systems with delocalized π-electrons, follow the Hückel rule, conferring significant stability to heterocyclic structures. The incorporation of heteroatoms, such as nitrogen, oxygen, and sulphur, within these rings profoundly influences electron distribution, molecular reactivity, and synthetic pathways. …
Published in International Journal of Chemical Synthesis and Chemical Reactions · Vol. 11, Issue 2, 2026 · pp. 1–7 Read article
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Investigation of Thermo-Acoustic Properties of Ethanol-Cyclohexane Binary Mixture
Abstract: The density, viscosity, and speed of sound for ethanol-cyclohexane binary mixtures were determined across mole fractions ranging from 0.1 to 0.9 using an Anton Paar DSA 5000 M within the temperature span of 288.15–318.15 K. From these experimental measurements, several thermodynamic and acoustic properties, such as isentropic compressibility, relative association, free volume, relaxation time, Gibbs free energy of activation, internal pressure, and solubility parameter, were derived. These parameters serve as …
Published in International journal of Thermodynamics and Chemical Kinetics · Vol. 11, Issue 2, 2025 · pp. 1–14 Read article
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Biocatalytic Synergy: Organic Chemistry Strategies for Sustainable Biochemical Transformation
Abstract: In the pursuit of greener and more sustainable chemical processes, biocatalysis has emerged as a pivotal field bridging organic chemistry with biochemical innovation. This paper explores how principles from organic chemistry are being integrated into biocatalytic systems to enable environmentally friendly biochemical transformations. Emphasis is placed on enzyme engineering, co-factor recycling, green solvent usage, and hybrid chemo-enzymatic methodologies that enhance selectivity, reduce toxicity, and minimize environmental impact. Recent advancements—including machine …
Published in International Journal of Industrial Biotechnology and Biomaterials · Vol. 11, Issue 2, 2025 · pp. 38–41 Read article
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Review Article: Butyl and Halo-Butyl Rubbers
Abstract: Butyl and halo butyl rubbers are key raw materials for various industries due to their exceptional properties, like permeability to gases, high chemical resistance, and durability. Butyl rubber (IIR) is composed of isobutylene with small amounts of isoprene, offering a low permeability to gases, making it ideal for applications in the automotive, medical, and consumer goods. Butyl Rubber is non-polar nature and possess excellent insulation properties which further enhance its …
Published in International Journal of Polymer Science and Engineering · Vol. 11, Issue 2, 2025 Read article
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Thermo-Acoustic Investigation of Molecular Interactions in Aqueous Solutions of L-Histidine at Different Temperatures
Abstract: The present study investigates the acoustic and thermodynamic behavior of aqueous solutions of L-Histidine across a concentration range of 0.01 m to 0.1 m and temperatures varying from 293.15 K to 318.15 K in 5 K intervals. Ultrasonic velocity (μ), density (ρ), and viscosity (η) measurements wereconducted with high precision to understand the solution behavior under different thermal conditions.Temperature constancy during measurements was ensured using a refrigerated circulatory bath withwater …
Published in International journal of Thermodynamics and Chemical Kinetics · Vol. 11, Issue 2, 2025 · pp. 9–17 Read article
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Greener ways of synthesizing Styrene oxide
Abstract: Styrene oxide is a key intermediate used in the fragrance, flavour, polymer and pharmaceutical industries, basically synthesized through processes such as epoxidation followed by distillation. These methods generate effluents that give rise to significant environmental challenges and rendering large-scale commercial production non-viable. The urgency for a greener and more economically viable synthesis routes has given rise to the exploration of alternative methods that produces lesser effluent generation. Enzymatic synthesis offers …
Published in International Journal of Green Chemistry · Vol. 11, Issue 2, 2025 · pp. 14–20 Read article
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Industrial Biotechnology and Circular Economy: A Pathway to Sustainable Bio-Manufacturing
Abstract: Industrial biotechnology, also known as white biotechnology, represents the application of biological systems and organisms in industrial processes, focusing on the production of bio-based products, including biofuels, chemicals, and materials. With the pressing need for sustainable manufacturing practices to address environmental degradation, resource depletion, and climate change, integrating industrial biotechnology with the principles of the circular economy offers an innovative pathway to ensure sustainability. The circular economy, which focuses on …
Published in International Journal of Industrial Biotechnology and Biomaterials · Vol. 11, Issue 1, 2025 · pp. 17–21 Read article
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Green Solvent Extraction: Sustainable Approaches for Chemical Separation
Abstract: Solvent extraction techniques have advanced significantly as a result of the increased focus on sustainability and environmental responsibility. Traditional organic solvents, while effective in chemical separation processes, often contribute to environmental pollution and pose health risks. In response, researchers have explored greener alternatives that minimize these adverse effects. Compared to traditional procedures, green solvent extraction offers safer and more environmentally friendly solutions by using bio-based solvents, ionic liquids, and deep …
Published in International Journal of Chemical Separation Technology · Vol. 11, Issue 1, 2025 Read article
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Liquid-Liquid Extraction Strategies for the Isolation of Bioactive Heterocyclic Compounds
Abstract: Liquid-liquid extraction (LLE) is a widely employed technique for the isolation of bioactive heterocyclic compounds from natural products, fermentation broths, and synthetic mixtures. The efficiency of LLE depends on several factors, including solvent selection, pH manipulation, salting-out effects, and temperature control. Conventional solvent systems, such as water-organic solvent pairs, are commonly used, while advanced strategies, including ionic liquids (ILs), deep eutectic solvents (DESs), ultrasound-assisted extraction (UAE), and microwave-assisted extraction (MAE), …
Published in International Journal of Chemical Separation Technology · Vol. 11, Issue 1, 2025 Read article
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Role of Human Carboxylesterase’s in Xenobiotics Metabolism
Abstract: According to one definition, xenobiotics are alien compounds that interfere with an organism's natural metabolism. Many xenobiotics can have a number of harmful effects if they don't have metabolism. There are several phase 1 metabolizing enzymes of xenobiotics which have capability to detoxify the toxic compounds. Several important metabolic detoxication enzymes are presented, including the mammalian microsomal cytochrome Carboxylesterases. Mammalian carboxyleterases are key enzymes from the serine hydrolase enzyme. Carboxylesterases …
Published in International Journal of Chemical Engineering and Processing · Vol. 11, Issue 1, 2025 · pp. 13–22 Read article
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Originative Approaches in Powder Formulation for Enhanced Therapeutic Efficacy
Abstract: Powder formulation is a cornerstone in the pharmaceutical industry, playing a vital role in improving drug efficacy and ensuring optimal therapeutic outcomes. However, traditional formulation methods often face significant challenges, such as poor solubility and low bioavailability, which can limit the effectiveness of many drugs. To address these issues, innovative strategies have emerged, including amorphous solid dispersions (ASDs), nanotechnology, and advanced manufacturing techniques like spray drying and hot melt etrusion. …
Published in International journal of Nanobiotechnology · Vol. 11, Issue 1, 2025 · pp. 1–10 Read article
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Eco-Friendly Chemical Processes: The Role of Green Chemistry in Modern Industries
Abstract: Green chemistry focuses on the development of chemical products and processes that minimize or eliminate hazardous substances, promoting sustainability throughout the chemical life cycle. Unlike environmental chemistry, which studies pollutants, green chemistry proactively designs safer alternatives to prevent environmental damage. This field spans multiple disciplines, including organic, inorganic, analytical, and physical chemistry, with applications across pharmaceuticals, manufacturing, and materials science. Key Principles of Green Chemistry Green chemistry is guided by …
Published in International Journal of Green Chemistry · Vol. 11, Issue 2, 2025 Read article
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Synthesis of Brominated Poly (Isobutylene-co-Isoprene) Based Ionomers and Its Applications
Abstract: Reactive bromobutyl rubber and its modification have been studied in detail. These reactive bromobutyl rubber was converted to ammonium and phosphonium functionalized bromobutyl rubber using triphenyl phosphine (PPh3) and 4-Dimethylaminopyridine (4-DMAP). Mechanical properties of synthesized ionomers are found comparative with butyl rubber. Pharma stopper was made from synthesized phosphonium ionomer that may be useful for pharma industries due to its self-healing characteristics which can help to preserve the properties of …
Published in International Journal of Composite Materials and Matrices · Vol. 11, Issue 1, 2025 · pp. 47–55 Read article
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Innovative Approaches to Molecular Synthesis for Drug Development
Abstract: The rapidly evolving field of drug development continually seeks innovative methodologies to enhance the efficiency, specificity, and scalability of molecular synthesis. This paper explores recent advancements in synthetic chemistry, focusing on techniques that have shown significant promise in addressing the challenges faced in drug discovery and development. Automated Synthesis: The advent of machine learning and artificial intelligence (AI) in synthetic chemistry has led to the development of automated synthesis platforms. …
Published in International Journal of Chemical Engineering and Processing · Vol. 10, Issue 2, 2024 · pp. 9–14 Read article
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Royal Jelly: A Brief Review of Nano and Micro Carriers and Potential Applications
Abstract: Royal Jelly, a bioactive substance known for its rich composition of proteins, lipids, and minerals, possesses significant antioxidant, antimicrobial, and anti-inflammatory properties. However, its instability in the presence of light, heat, and oxygen limits its practical applications. Recent advancements in nanotechnology, mainly using nanoparticles combined with microencapsulation techniques, have shown promise in enhancing royal jelly’s stability, bioavailability, and controlled release. This brief review explores encapsulated royal jelly’s biological effects and …
Published in International Journal of Environmental Chemistry · Vol. 11, Issue 1, 2025 · pp. 34–48 Read article
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Nanomaterials via Green Synthesis: Insights into Biocompatibility and Biotechnological Applications
Abstract: This review critically examines recent advances in the green synthesis of nanomaterials (NMs) and their diverse biological applications, with a focus on antimicrobial, antioxidant, anticancer, and anti-inflammatory properties. The reviewed studies evaluated key characteristics of green-synthesized NMs, including their size, shape, and concentrations, as assessed in both in vitro and in vivo biological models. Compared to traditional chemical methods, green synthesis demonstrated superior efficacy, enhanced biocompatibility, and reduced toxicity. For …
Published in International Journal of Green Chemistry · Vol. 11, Issue 1, 2025 · pp. 1–16 Read article
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Cell Culture Technologies in Animal Biotechnology: Innovations and Applications
Abstract: Cell culture technologies have become integral to animal biotechnology, enabling the in vitro study of cellular behaviors, disease mechanisms, and the development of therapeutic solutions. These technologies are foundational for advancements in drug discovery, gene therapy, regenerative medicine, and vaccine production. Over recent decades, innovations in culture media, bioreactor systems, and three-dimensional (3D) cell culture models have significantly enhanced the efficiency and reproducibility of cell-based research. Serum-free and chemically defined …
Published in International Journal of Animal Biotechnology and Applications · Vol. 10, Issue 2, 2024 · pp. 25–29 Read article