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257 articles for “Drug”
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Malayalam Translation of Personal Drug Use Questionnaire (SOCRATES-8D): Process and Challenges
Abstract: Motivation to change and treatment participation is an important determinant of treatment outcome measurement among patients diagnosed with substance use disorders. SOCRATES is a widely used instrument assessing the motivation of patients with SUDs. In this study, the authors discuss the steps adopted and the challenges in translating SOCRATES 8D into Malayalam from its original English version.
Published in International journal of Nursing Science Practice and Research · Vol. 9, Issue 1, 2023 · pp. 1–4 Read article
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A Comparative Study of Intravenous Paracetamol and Intravenous Diclofenac for Post-operative Pain Relief
Abstract: Despite advancements reducing mortality rates, adverse effects such as pain, nausea, and vomiting remain prevalent and can hinder recovery. Pain is now considered the fifth vital sign, as defined by the International Association for the Study of Pain, and inadequate pain management can result in prolonged hospital stays, increased drug use, and delayed recovery. Effective postoperative pain control is crucial in preventing respiratory complications and facilitating early discharge and return …
Published in International Journal of Analytical and Applied Chemistry · Vol. 11, Issue 1, 2025 · pp. 50–56 Read article
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Review on Development of Ethosomal Formulation of Ginger
Abstract: Transdermal drug delivery, self-contained, discrete dosage forms which, when applied to the skin, deliver the drug, through the skin at controlled rate to the systemic circulation. Ethosomes, noninvasive delivery carriers that enable drugs to reach deep into the skin layers or the systemic circulation which is made up of phospholipids, ethanol and water. This review article summarizes structure, advantages, disadvantages, composition of ethosomes and mechanism of drug penetration, method of …
Published in International Journal of Industrial Biotechnology and Biomaterials · Vol. 6, Issue 1, 2020 · pp. 8–14 Read article
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Targeted Nanotherapy and Advanced Biosensing: A Novel Approach to Preventing and Treating Fibrodysplasia Ossificans Progressiva
Abstract: Fibrodysplasia ossificans progressiva (FOP) is an exceptionally rare and debilitating genetic disorder marked by the gradual transformation of soft tissues into bone, severely impairing movement and reducing lifespan. This review delves into the potential of cutting-edge nanotherapy and advanced biosensing technologies as novel strategies for both preventing and treating FOP. Nanotechnology could help make targeted drug delivery systems and real-time monitoring tools that can precisely target the mutant ACVR1 gene, …
Published in International journal of Nanobiotechnology · Vol. 10, Issue 2, 2024 · pp. 11–18 Read article
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Nanocapsules Applied in Pharmaceutical Delivery Systems
Abstract: Nanocapsules, which are minute vesicles composed of a parent material shielded by a polymer casing to encase the drug in the nucleus while regulating the drug’s dispensation and targeting capacity, represent a ground-breaking advancement in the realm of pharmaceuticals. The purpose behind the creation of nanocapsules is to enhance their efficiency and functionality by leveraging various methodologies like polymerization, solvent diffusion, dialysis, and supercritical fluid technology. These nanocapsules introduce a …
Published in International journal of Nanobiotechnology · Vol. 10, Issue 2, 2024 · pp. 1–10 Read article
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Nanomedicine—Present and Future of Disease Management
Abstract: Nanotechnology presently has many uses in practically every one of the fields. The introduction of nanomedicine has benefitted many research areas in pharmaceutical industries. The usage of nanoparticles in drugs has shown great results that the other drugs did not. In the development of novel medicine, nanotechnology is playing an important role. It is because few medications cannot be used due to complications such as its toxicity, this can be …
Published in International journal of Nanobiotechnology · Vol. 8, Issue 1, 2022 · pp. 20–25 Read article
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Nanosuspension-novel Technique for Solubility Enhancement
Abstract: In the treatment of many diseases, getting medicinal compounds to the desired location is a serious issue. Poor biodistribution, limited effectiveness, unfavorable side effects, and a lack of selectivity define traditional medication use. Different types of nanostructures are produced using various size reduction processes and technologies, each with its own set of physicochemical and biological features. These technologies make nanostructures a good material for biomedical applications, and they've gained a …
Published in International Journal of Nanomaterials and Nanostructures · Vol. 7, Issue 2, 2021 · pp. 18–24 Read article
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Microscopic Avengers: The Rise of Nanorobots in Biomedical Engineering
Abstract: Nanorobotics is an emerging field at the intersection of nanotechnology and robotics, offeringa promising new frontier in biomedical engineering. Nanorobots, at the scale of a fewhundred nanometres, are designed to perform a variety of tasks within the human body,ranging from targeted drug delivery to precise surgical procedures. This article explores theevolution, design, functionality, and applications of nanorobots in biomedical engineering,highlighting their potential to revolutionize healthcare.The evolution of nanorobots has seen …
Published in International Journal of Nanomaterials and Nanostructures · Vol. 9, Issue 2, 2023 · pp. 10–15 Read article
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Nanomaterials in Modern Medicine: Synthesis,Applications, and Future Prospects
Abstract: Nanomaterials have significantly transformed the biomedical landscape, offering novelsolutions for diagnosis, treatment, and disease prevention. Their distinct physicochemicalcharacteristics such as a high surface area-to-volume ratio, tunable surface chemistry, andimproved bioavailability enable precise interactions with biological systems at the molecularlevel. This review presents a comprehensive examination of the synthesis methods andcharacterisation techniques employed to develop biomedical-grade nanomaterials, highlightingtheir structural and functional optimisation for clinical applications. Key areas of applicationdiscussed include targeted …
Published in International Journal of Nanomaterials and Nanostructures · Vol. 11, Issue 2, 2025 Read article
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Polymer-Based Composites in Orthopedic Applications: A Study
Abstract: The pursuit of ideal biomaterials in the field of orthopaedics is an ongoing process that is drivenby the requirement for improved biocompatibility, mechanical congruence with natural tissues,and long-term stability in vivo. Polymer-based composites, also known as PBCs, have emergedas highly attractive options. These composites offer a one-of-a-kind combination of features thatcan be customised, which addresses many of the constraints that are associated with standardceramic and metallic implants. The purpose of …
Published in International Journal of Composite and Constituent Materials · Vol. 11, Issue 2, 2025 Read article
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Innovative Approaches to Organic and Inorganic Nanocomposite Synthesis: Chemical Reaction Pathways
Abstract: The integration of organic and inorganic nanomaterials has emerged as a prominent trend in various sectors, driven by the unique properties and functionalities that nanoscale materials offer. This study elucidates the current landscape of organic-based nanomaterials, highlighting their synthesis, characterization, and application potential across different fields. The miniaturization principle has catalyzed the development of nanocomposites that combine inorganic and organic constituents, enhancing the reactivity and performance of traditional materials through …
Published in International Journal of Chemical Synthesis and Chemical Reactions · Vol. 10, Issue 2, 2025 · pp. 1–9 Read article
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Nanotechnology in Healthcare Applications: A Study
Abstract: Nanotechnology has arisen as a transformative field with vast potential in healthcare applications, promising to revolutionize diagnostics, therapeutics, and overall patient management. Nanotechnology manipulates molecules and atoms, creating materials and devices with extraordinary properties. This study aims to sightsee the various solicitations of nanotechnology in healthcare, highlighting its benefits, challenges, and prospects. Targeted Medication Delivery: Nanotechnology enables the design of sophisticated drug delivery systems, precisely tailoring dosage and release for …
Published in International journal of Nanobiotechnology · Vol. 10, Issue 2, 2024 · pp. 49–59 Read article
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Virosomes: Understanding the Modern Concepts and Latest Applications
Abstract: A virosome is a cutting-edge hybrid drug delivery method that combines the benefits of viral and non-viral vectors. A virosome has been shown to transport a variety of physiologically active substances, including nucleic acids, peptides, proteins, and tiny chemical compounds, according to research. Surface changes of virosomes may be used to enable targeted medication delivery utilising virosome-based devices. There are presently a variety of virosome-based preventive and therapeutic medicines on …
Published in International Journal of Animal Biotechnology and Applications · Vol. 7, Issue 1, 2021 · pp. 20–31 Read article
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Current status on the preparation method and applications of iron oxide nanomaterials: A review
Abstract: Iron oxide nanoparticles are now gaining interests in the field of nanobiotech and pharmaceuticals for their important applications. The target oriented drug delivery of Fe3O4 has gained more attention for various advantages of it. Iron oxide magnetic nanoparticles focus on offering local drug delivery, reduced side effects and controlled drug release for prolonged period of time addressing problems of health tissue damage and drug waste. In this review, we discuss …
Published in International Journal of Analytical and Applied Chemistry · Vol. 4, Issue 2, 2018 · pp. 1–12 Read article
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Molecular Docking of Catharanthus Roseus Bioactive Compounds of Targetinging Bovine Leukaemia Virus
Abstract: Therapeutic potential of Catharanthus roseus bioactive compounds as the 4PHO protein inhibitors, a pathogenetic determinative factor of BLV. This work describes the use of computational drug discovery approaches in estimating the interactions conducted between 40 phytocompounds of Catharanthus roseus and the 4PHO protein. Our work has determined the presence of Pamoic acid and Vindolinine hydrochloride as the optimal choice here. Pharmacokinetic screening exhibited drug-like properties to both the highly absorbed …
Published in International Journal of Animal Biotechnology and Applications · Vol. 11, Issue 2, 2025 · pp. 19–31 Read article
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Originative Approaches in Powder Formulation for Enhanced Therapeutic Efficacy
Abstract: Powder formulation is a cornerstone in the pharmaceutical industry, playing a vital role in improving drug efficacy and ensuring optimal therapeutic outcomes. However, traditional formulation methods often face significant challenges, such as poor solubility and low bioavailability, which can limit the effectiveness of many drugs. To address these issues, innovative strategies have emerged, including amorphous solid dispersions (ASDs), nanotechnology, and advanced manufacturing techniques like spray drying and hot melt etrusion. …
Published in International journal of Nanobiotechnology · Vol. 11, Issue 1, 2025 · pp. 1–10 Read article
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Nanocarrier Technologies of the Lemon Essential Oils: Brief Review
Abstract: This review article delves into integrating nanoparticles with essential oils, focusing on lemon essential oil (LEO) and recent advancements in nanocarrier technologies and their biotechnological applications. It systematically outlines the methodologies for synthesizing various nanostructured systems, including liposomes, solid lipid nanoparticles (SLNs), and nanoemulsions, emphasizing their critical role in enhancing the bioactivity of LEO. Moreover, the review provides a comprehensive analysis of the advantages and limitations of each nanocarrier type, …
Published in International Journal of Environmental Chemistry · Vol. 11, Issue 1, 2025 · pp. 20–33 Read article
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Different Method for the Production of OxadiazoleCompounds
Abstract: The creation of procedures for the environmentally friendly synthesis of materials and chemicals isreferred to as "green synthetic protocol." The synthesis of different biologically active compounds isdone through energy-efficient and environmentally safe processes like microwave irradiationtechnology, ultrasound-mediated synthesis, photo-catalysis (ultraviolet, visible, and infraredirradiation), molecular sieving, grinding, and milling techniques, etc. These procedures are regardedas sustainable technology and have gained value as green protocols for the synthesis of novelmedicinal compounds because …
Published in International Journal of Chemical Engineering and Processing · Vol. 10, Issue 1, 2024 · pp. 20–26 Read article
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Advancement of Poly-(ADP – Ribose) Polymerase (PARP) Inhibitors in Cancer Progression and Treatment
Abstract: DNA repair mechanisms are the most common and potential targets in cancer treatment. PARP enzymes play a crucial role in detection of DNA damage and its repair and also in apoptosis. Detailed knowledge of these mechanisms leads to the development of poly-(ADP-Ribose) polymerase (PARP) inhibitors as vigorous anticancer drugs with specific action. PARP inhibitors can selectivity kill tumours with deficiencies in DNA repair proteins like BRCA1/2, exploiting synthetic lethality concept. …
Published in International Journal of Animal Biotechnology and Applications · Vol. 1, Issue 1, 2015 Read article
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RECENT TRENDS IN APPLICATIONS OF NANOTECHNOLOGY
Abstract: The field of pharmaceutical and nanotechnology has been growing rapidly.This review will provide the recent advancement that in the field of nanotechnology .It will focus on the development of multifunctional particles for drug delivery. The current nanotechnology studies have been growing in chemistry and medicine because of applications of nanomaterials mainly in Chemical Engineering, Biochemistry, Genetics and Molecular Biology.
Published in International Journal of Applied Nanotechnology · Vol. 1, Issue 1-2, 2015 Read article