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257 articles for “Drug”
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Study of the Effect of SLS Loading on the One-Pot Synthesis of Substituted Piperidines
Abstract: Piperidine derivatives represent a vital class of nitrogen-containing heterocycles with extensive pharmacological and industrial significance. Their synthesis has garnered considerable interest due to their presence in numerous bioactive molecules, including drugs with CNS activity, analgesic properties, and antimicrobial effects. Traditional multi-step synthetic pathways are often time-consuming and resource-intensive. To address this, one-pot multicomponent reactions (MCRs) have emerged as an efficient and eco-friendly alternative, allowing for the rapid construction of complex …
Published in International Journal of Green Chemistry · Vol. 12, Issue 1, 2026 · pp. 1–9 Read article
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A Case Study on Interstitial Lung Diseases (ILD)
Abstract: Interstitial lung diseases (ILDs) represent a diverse group of diffuse parenchymal lung disorders characterized by significant morbidity and mortality worldwide. Recent advances have led to the development of a new classification system for idiopathic interstitial pneumonias, dividing them into major, rare, and unclassified groups, with a novel approach based on disease behavior. Idiopathic pulmonary fibrosis (IPF) remains the most fatal ILD, demonstrating considerable clinical heterogeneity and poor prognosis. Early diagnosis …
Published in International Journal of Medical Surgical Nursing · Vol. 8, Issue 2, 2025 · pp. 13–20 Read article
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Economical ways to synthesize Nucleotides from Safe and Cheaper raw materials
Abstract: Cytosine is a fundamental nitrogenous base present in both DNA and RNA, playing a critical role inessential cellular processes such as replication, transcription, gene regulation, signal transduction, andDNA repair. Due to its central biological importance, the efficient and cost-effective synthesis of cytosinehas garnered significant interest across biochemical, pharmaceutical, and industrial sectors. However,most conventional synthetic methods rely on complex enzymatic transformations or require expensiveand structurally elaborate starting materials, thereby limiting their …
Published in International Journal of Chemical Synthesis and Chemical Reactions · Vol. 11, Issue 2, 2026 · pp. 1–7 Read article
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Economical ways to synthesize Nucleotides from Safe and Cheaper raw materials
Abstract: Cytosine is a fundamental nitrogenous base present in both DNA and RNA, playing a critical role inessential cellular processes such as replication, transcription, gene regulation, signal transduction, andDNA repair. Due to its central biological importance, the efficient and cost-effective synthesis of cytosinehas garnered significant interest across biochemical, pharmaceutical, and industrial sectors. However,most conventional synthetic methods rely on complex enzymatic transformations or require expensiveand structurally elaborate starting materials, thereby limiting their …
Published in International Journal of Chemical Synthesis and Chemical Reactions Read article
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Eco-Friendly Chemical Processes: The Role of Green Chemistry in Modern Industries
Abstract: Green chemistry focuses on the development of chemical products and processes that minimize or eliminate hazardous substances, promoting sustainability throughout the chemical life cycle. Unlike environmental chemistry, which studies pollutants, green chemistry proactively designs safer alternatives to prevent environmental damage. This field spans multiple disciplines, including organic, inorganic, analytical, and physical chemistry, with applications across pharmaceuticals, manufacturing, and materials science. The principles of green chemistry, first formulated by Paul Anastas …
Published in International Journal of Green Chemistry · Vol. 11, Issue 2, 2025 · pp. 14–28 Read article
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Recent Trends in Bio Ceramic and Polymer Compositesfor Biomedical and Dental Applications
Abstract: Advanced biomaterials with great promise for use in dental and biomedical applications are bio-ceramic and polymer composites. These composites combine the flexibility, biodegradability, and processability of polymers with the mechanical strength, bioactivity, and biocompatibility of bio-ceramics. Clinical success is often limited by the biological response and tissue compatibility of conventional materials such as metals and single-phase ceramics. Oste conductivity and bone-like characteristics are exhibited by bio-ceramic materials, such as hydroxyapatite …
Published in International Journal of Composite Materials and Matrices · Vol. 11, Issue 2, 2025 · pp. 1–5 Read article
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Nano-Sensors in Cancer care: A Study
Abstract: Cancer remains a leading cause of mortality worldwide, highlighting the urgent need forinnovative approaches to early detection, accurate diagnosis, and effective treatment. Traditionalmethods often fall short in identifying cancer at its nascent stages or lack the precision requiredfor personalized therapies. Emerging nanotechnology, particularly the development of nano-sensors, offers a promising solution to address these limitations, paving the way for a new era incancer care. This article explores the transformative potential …
Published in International journal of Nanobiotechnology · Vol. 11, Issue 2, 2025 Read article
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Synthesis, computational analysis and biological evaluation of novel thiazolidinone derivatives
Abstract: Through multicomponent methods including 2-chloroquinoline-3-carbaldehyde,(1- methylpiperidin-4-yl) methanamine and thioglycolic acid, the work focuses on creating and assessing the antibacterial characteristics of a new 4-thiazolidinone heterocyclic. Spectral testing was used to validate the molecules' structures. All the compounds were screened for their antibacterial and antifungal activity using Agar-well diffusion; compared to the reference drugs such as Ampicillin, Ciprofloxacin, and Griseofulvin, the examined compounds demonstrated moderate to good efficacy, with inhibition zone …
Published in International Journal of Analytical and Applied Chemistry · Vol. 11, Issue 2, 2025 · pp. 30–40 Read article
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Nano-Sensors in Cancer care: A Study
Abstract: Nano, Sensors, Cancer, Healthcare, Nanoscale, Nanoparticles. Abstract: Cancer remains a leading cause of mortality worldwide, highlighting the urgent need for innovative approaches to early detection, accurate diagnosis, and effective treatment. Traditional methods often fall short in identifying cancer at its nascent stages or lack the precision required for personalized therapies. Emerging nanotechnology, particularly the development of nano-sensors, offers a promising solution to address these limitations, paving the way for a …
Published in International journal of Nanobiotechnology · Vol. 11, Issue 2, 2025 Read article
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A Descriptive Study to Assess the Prevalence and Risk Factors Associated with Headache Among Students at Selected College,Coimbatore.
Abstract: One of the most prevalent neurological conditions is headache. According to estimates, about 50% of adults experienced a headache at least once in the previous 12 months. A headache has a significant impact on a person's life and interferes with social, professional, and recreational activities. The main aim of the study was to assess the prevalence and risk factors associated with headache among students at selected college, Coimbatore. A Quantitative, …
Published in International journal of Nursing Science Practice and Research · Vol. 11, Issue 2, 2025 · pp. 31–38 Read article
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Nanorobotics in Cancer Treatment: A Study
Abstract: Cancer, a complex and devastating disease, continues to plague humanity. There have been great advancements achieved in conventional treatments, such as chemotherapy and radiation; however, these treatments frequently come with serious adverse effects and limited efficacy against certain types of tumors. In the relentless pursuit of more targeted and effective therapies, nanorobotics has emerged as a promising frontier. This article explores the potential of nanorobots in revolutionizing cancer treatment, drawing …
Published in International Journal of Nanomaterials and Nanostructures · Vol. 11, Issue 1, 2025 · pp. 44–52 Read article
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Natural Polymers as Substitutes for Gelatine Capsules: A Comprehensive Overview
Abstract: Gelatine capsules are widely used in the pharmaceutical and nutraceutical industries for over a century due to their easy-to-swallow nature and their ability to release pharma active ingredients in a controlled manner. However, due to growing concerns over health, ethical issues, and environmental issues associated with the use of animal-derived products, there has been a significant interest towards developing natural, plant-based, and synthetic alternatives to gelatine. This article briefly explores …
Published in International Journal of Polymer Science and Engineering · Vol. 11, Issue 1, 2025 · pp. 9–13 Read article
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Synthesis of Brominated Poly (Isobutylene-co-Isoprene) Based Ionomers and Its Applications
Abstract: Reactive bromobutyl rubber and its modification have been studied in detail. These reactive bromobutyl rubber was converted to ammonium and phosphonium functionalized bromobutyl rubber using triphenyl phosphine (PPh3) and 4-Dimethylaminopyridine (4-DMAP). Mechanical properties of synthesized ionomers are found comparative with butyl rubber. Pharma stopper was made from synthesized phosphonium ionomer that may be useful for pharma industries due to its self-healing characteristics which can help to preserve the properties of …
Published in International Journal of Composite Materials and Matrices · Vol. 11, Issue 1, 2025 · pp. 47–55 Read article
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Postoperative Pain Management: Understanding the Role of NSAIDs and Analgesics
Abstract: Postoperative pain management is a critical aspect of clinical care, with a significant impact on patient recovery and quality of life. Among the pharmacological options available, Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) and acetaminophen (paracetamol) are widely utilized due to their distinct chemical properties and mechanisms of action. This study aims to evaluate and compare the efficacy of intravenous paracetamol (C₈H₉NO₂) and diclofenac (C₁₄H₁₁Cl₂NO₂) in postoperative analgesia, focusing on their pharmacokinetic profiles, …
Published in International Journal of Chemical Synthesis and Chemical Reactions · Vol. 11, Issue 1, 2026 · pp. 36–42 Read article
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Role of Cloud Computing in Chemistry
Abstract: Cloud computing has emerged as a transformative technology in the field of chemistry, offering unprecedented computational power, data storage, collaborative capabilities, and enhancing the performance of spectroscopic techniques. The integration of cloud-based platforms in chemical research facilitates complex molecular simulations, big data analysis, and real-time collaboration among researchers worldwide. By leveraging cloud infrastructure, chemists can perform high-throughput virtual screenings, predict molecular behaviors, and model chemical reactions with greater efficiency and …
Published in International Journal of Chemical Engineering and Processing · Vol. 10, Issue 2, 2024 · pp. 1–15 Read article
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Trending Aspects of Green Synthesis of Silver Nanoparticles and Their Biomedical Applications: A Review
Abstract: For the past few decades, researchers have been fascinated by nanotechnology and nanoparticles due to their unique physico-chemical characteristics, such as increased surface area, reduced size, and improved reactivity, making them useful for various industrial, scientific, and medicinal applications. Silver nanoparticles are widely used, particularly in the biomedical sciences, since they are less toxic than other metal nanoparticles, meaning that they do not harm healthy human or host cells. They …
Published in International Journal of Green Chemistry · Vol. 11, Issue 1, 2025 · pp. 1–27 Read article
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Advances in Copolymer Synthesis and Their Industrial Applications
Abstract: Copolymers, composed of two or more distinct monomers, have seen tremendous growth due to their adaptability in creating materials with enhanced properties for diverse applications. Recent advances in synthesis techniques, such as controlled radical polymerization (CRP), ring-opening polymerization (ROP), and living polymerization have enabled precise control over copolymer architectures, offering tailored properties, such as improved thermal stability, flexibility, and biodegradability. These advancements have had a transformative impact across various industrial …
Published in International Journal of Industrial Biotechnology and Biomaterials · Vol. 10, Issue 2, 2024 · pp. 51–56 Read article
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A Study to analyze compliance to timing of thrombolytic loading dose among patient with acute myocardial infarction and its impact on patient outcomes
Abstract: Thrombolytic medications work by breaking down large blood clots, allowing blood to flow back to the heart and reducing the risk of heart muscle damage. These agents can help prevent a heart attack from progressing to a myocardial infarction, which can be life-threatening. Fibrinolytic drugs are the preferred treatment for STEMI, as they promote reperfusion and restore blood flow when given within 12 hours of symptom onset. A 12- hour …
Published in International Journal of Nursing Critical Care · Vol. 10, Issue 2, 2024 · pp. 1–11 Read article
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Harnessing the Power of CRISPR in Animal Biotechnology
Abstract: CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) technology has revolutionized genetic engineering, ushering in a new era of advancements in biotechnology. Derived from the adaptive immune system of bacteria, the CRISPR-Cas9 system offers unparalleled precision and efficiency in genome editing. Its applications in animal biotechnology are extensive, encompassing livestock improvement, disease resistance, and biopharmaceutical production, as well as environmental conservation. In livestock, CRISPR has enabled the enhancement of desirable traits, …
Published in International Journal of Animal Biotechnology and Applications · Vol. 10, Issue 2, 2024 · pp. 6–10 Read article
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Analyses of Polymer Nanocomposites Development in Biomedical Applications
Abstract: Polymer nanocomposites (PNCs) are known for being an effective method to impart materials with exceptional properties that cannot be achieved by the individual components on their own. Utilizing the interfaces between the two phases of nanoscale compounds with high specific surface areas is advantageous for creating composites that incorporate nanofillers. The primary difficulty with nanocomposites lies in managing the interfacial interactions between the two phases. Polymer nanocomposites have gained significant …
Published in International Journal of Applied Nanotechnology · Vol. 10, Issue 2, 2024 · pp. 23–38 Read article