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19 articles for “Metabolic Disorder”
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Nanostructures: Advancing Targeted Metabolic Engineering for Treating Metabolic Disorders.
Abstract: Nanostructures have emerged as powerful tools in the field of targeted metabolic engineering,offering precise control over metabolic pathways in specific cells or tissues. This technologyholds great promise for treating a wide range of metabolic disorders by modulating cellularmetabolism at the nanoscale.One of the key advantages of nanostructures in metabolic engineering is their ability to targetspecific cells or tissues with high precision. By encapsulating or delivering metabolicmodulators such as enzymes, cofactors, …
Published in International Journal of Nanomaterials and Nanostructures · Vol. 9, Issue 2, 2023 · pp. 16–21 Read article
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Enhancing Fertility in Dairy Cows: Integrating Nutritional, Hormonal, and Technological Approaches for Optimal Reproductive Health
Abstract: Enhancing fertility in dairy cows is crucial for improving reproductive efficiency, ensuring sustainable dairy production, and optimizing herd health. This study explores the integration of nutritional, hormonal, and technological approaches to achieve optimal reproductive outcomes. Nutritional interventions, including macro- and trace minerals, vitamins, protein supplements, and energy boosters, are critical in supporting the physiological demands of dairy cows, particularly during transition periods and lactation. Hormonal therapies such as progesterone, GnRH …
Published in International Journal of Animal Biotechnology and Applications · Vol. 12, Issue 1, 2026 Read article
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A Comprehensive Review on Fecal Microbiota Transplantation
Abstract: Fecal microbiota transplantation (FMT) has emerged as a groundbreaking therapeutic approach in restoring gut microbiome balance and treating various gastrointestinal disorders. This comprehensive review synthesizes current knowledge on FMT, examining its clinical applications, underlying mechanisms, safety profile, and future directions. Initially, FMT was primarily utilized for managing recurrent Clostridium difficile infection (CDI), demonstrating significant clinical efficacy and establishing its role in modern medicine. The review explores the evolving scope of …
Published in International Journal of Immunological Nursing · Vol. 10, Issue 2, 2024 Read article
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Cryogenic Electron Microscopy Reveals Conformational Dynamics and Catalytic Mechanisms of Human Fatty Acid Synthase in De Novo Lipid Biosynthesis
Abstract: Fatty acid synthase (FASN) is a multifunctional homodimeric enzyme central to de novo fatty acid synthesis in mammals. Recent cryogenic electron microscopy (cryo-EM) studies have illuminated the structural basis of FASN catalysis, revealing multiple conformational states throughout the synthesis cycle. These findings show that the acyl carrier protein (ACP) domain dynamically shuttles substrates between spatially separated active sites, while the condensing and modifying regions remain structurally stable. In contrast to …
Published in International Journal of Analytical and Applied Chemistry · Vol. 12, Issue 2, 2026 · pp. 8–25 Read article
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Isocoreopsin and Glycogen Phosphorylase – An in-silico Interaction Study: A New Way to Tackle Type 2 Diabetes (T2D)†
Abstract: The activity of glycogen phosphorylase (GP) plays a crucial role in regulating glycogen metabolism, and its excessive activity has been closely linked to the pathogenesis of metabolic disorders, such as type 2 diabetes (T2D). Therefore, targeting GP inhibition has emerged as a significant therapeutic strategy for managing this disease. Current research focuses on the discovery and development of novel small molecules capable of suppressing GP activity. Among these, flavonoids have …
Published in International Journal of Environmental Chemistry · Vol. 11, Issue 1, 2025 · pp. 76–80 Read article
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Operational Complexities in Commercial Dairy Farms: Insights into Feeding, Nutrition, Health, and Management Practices for Sustainable Dairy Development
Abstract: Commercial dairy farming faces diverse range of challenges that impact productivity, profitability, and sustainability. Feeding and nutrition remain critical, with fluctuating feed costs, inconsistent forage quality, and the need to balance dietary formulations for optimal milk yield and animal health. Nutritional deficiencies and imbalances can predispose dairy cows to metabolic disorders, compromising overall performance and longevity. Health challenges, including mastitis, lameness, and reproductive disorders, are exacerbated by inadequate management practices …
Published in International Journal of Animal Biotechnology and Applications · Vol. 11, Issue 1, 2025 · pp. 37–50 Read article
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Exploring Fecal Microbiota Transplantation: A Comprehensive Overview
Abstract: Fecal Microbiota Transplantation (FMT) has become a revolutionary treatment for rebalancing the gut microbiome, especially in patients with recurrent Clostridioides difficile infection (CDI). This comprehensive review delves into the evolution, methodologies, clinical applications, and future directions of FMT. Initially developed as a solution to combat severe gastrointestinal dysbiosis, FMT has demonstrated significant efficacy in treating CDI, with cure rates surpassing 80% in numerous studies. The review examines various FMT delivery …
Published in International Journal of Immunological Nursing · Vol. 10, Issue 2, 2024 · pp. 19–24 Read article
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Biosensors Powered by Nanotechnology forContinuous Insulin Delivery and GlucoseMonitoring in Diabetes Management
Abstract: Diabetes mellitus is a chronic metabolic disorder that necessitates continuous glucose monitoring and precise insulin delivery for effective management. Traditional methods often fall short in maintaining the necessary levels of accuracy and convenience, thereby posing challenges in achieving optimal glycemic control. Nanotechnology-enabled biosensors have revolutionized this field by leveraging the unique properties of nanomaterials, offering significant improvements in sensitivity, selectivity, and biocompatibility. This article delves deeply into the transformative role …
Published in International Journal of Applied Nanotechnology · Vol. 10, Issue 1, 2024 · pp. 13–24 Read article
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Cow’s milk trigger for type 1 diabetes
Abstract: Diabetes is an autoimmune, metabolic disorder that occurs when the pancreas stops producing insulin hormones. Type 1 diabetes or juvenile diabetes may occur genetically due to viral infection, vitamin D deficiency and environmental factors. Cow’s milk protein is one of the causes for type 1 diabetes. Casein protein which is found in the cow’s milk is responsible for production of antibodies bovine β–lacto globulin. Such antibodies destroy the β cell …
Published in International Journal of Animal Biotechnology and Applications · Vol. 9, Issue 1, 2023 · pp. 33–49 Read article
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A Simplified High-Performance Liquid Chromatographic Method For Determination of Vitamin D3 in Human Serum
Abstract: Diabetes is a metabolic disorder caused by defective insulin secretion, insulin action or both. The two major factors for the development of diabetes are pancreatic beta cell dysfunction and insulin resistance. In type 2 diabetes mellitus, production and release of insulin is unobstructed but due to factors like ageing or obesity, the produced insulin cannot compensate for the increased demand. Measurement of the serum level of 25-hydroxyvitamin D3 is the …
Published in International Journal of Analytical and Applied Chemistry · Vol. 3, Issue 1, 2017 · pp. 9–13 Read article
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Buerger-Allen Exercise on Foot Perfusion among Patients with Diabetes Mellitus
Abstract: Background of the study: Diabetes Mellitus (DM) is a metabolic disorder which is characterized withincreased glucose level in the blood, resulting from defect in the insulin secretion, insulin action, orboth. In advance stage of the disease, foot perfusion of patients is decreased. It can be assessed byAnkle Brachial Index (ABI), Capillary Refill Time (CRT) and Peripheral pulse rate. Buerger-Allenexercise is an effective intervention for improving the foot perfusion of diabetes …
Published in International Journal of Geriatric Nursing · Vol. 4, Issue 2, 2021 · pp. 27–33 Read article
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Depression in Diabetes Mellitus: A Review
Abstract: One of the major public health problems in 21st century is diabetes mellitus. In developed as well as developing countries the prevalence of diabetes is increasing day by day. Diabetes is considered as one of the most common causes of death and disabilities by WHO and IDF. It is a serious long-term metabolic disorder with a major impact on the lives and well-being of individuals, families, and societies worldwide. The …
Published in International journal of Nursing Science Practice and Research · Vol. 8, Issue 1, 2022 · pp. 1–8 Read article
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Advancing Early Detection of Menkes Disease Through Image Analysis and Biosensor Integration
Abstract: Menkes disease, a rare X-linked recessive disorder of copper metabolism, poses significant challenges in early diagnosis due to its nonspecific initial symptoms. This paper presents a comprehensive approach to enhance the early detection of Menkes disease by leveraging image processing techniques, pattern recognition algorithms, and innovative biosensor technologies. A novel framework is proposed that combines analysis of hair microscopy images, facial feature recognition, and copper-sensitive biosensors to create a multi-modal …
Published in International Journal of Image Processing and Pattern Recognition · Vol. 10, Issue 2, 2024 · pp. 24–34 Read article
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Therapeutic Massage useful for Diabetes Mellitus Patients
Abstract: Diabetes is a chronic condition that mainly occurs when the pancreas does not produce enough insulin or the body cannot effectively use the insulin it produced by hyperglycemia and other related disorders in the body’s metabolism can lead to serious damage to many of the body systems especially nerves and blood vessels. Diabetic complications are classified in to two major categories like acute and chronic. Diabetes patients use therapeutic massage …
Published in International Journal of Immunological Nursing · Vol. 3, Issue 1, 2017 · pp. 38–41 Read article
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Studies on Phytochemical analysis of Areca Palm Leaves
Abstract: Areca palm plant is commonly known as Palm trees and belongs to the family Arecaceae. Probablyone of the best and frequently grown plant families is the palm family. Palm trees are cultivating in South America, South Pacific area, Southern Asia, and Arabic countries etc. The greatest number of palm species may exist in Colombia. Palms are used to make a wide variety of everyday goods and cuisines. This palm plant …
Published in International Journal of Chemical Separation Technology · Vol. 8, Issue 1, 2022 · pp. 1–11 Read article
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Exploring the Connection Between Diabetes and Vision Loss in Older Adults
Abstract: Diabetes is a significant public health concern, particularly among older adults, where its prevalence is rising rapidly. One of the most serious complications of diabetes is its detrimental impact on eye health, leading to conditions, such as diabetic retinopathy, cataracts, and glaucoma. This review seeks to clarify the intricate connection between diabetes and vision loss in the elderly population. Diabetic retinopathy, which involves damage to the retina caused by prolonged …
Published in International Journal of Geriatric Nursing · Vol. 7, Issue 2, 2024 · pp. 1–4 Read article
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Managing Rabson–Mendenhall Syndrome: A Case Report
Abstract: Rabson–Mendenhall syndrome is an uncommon genetic disorder that presents with a range of distinct characteristics. These include stunted growth, abnormal physical features, such as coarse facial features and crowded teeth, and a lack of subcutaneous fat. Additionally, individuals with Rabson–Mendenhall syndrome may experience enlarged genitalia, excessive hair growth (hirsutism), and abnormal glucose regulation. Pineal hyperplasia, a condition characterized by the enlargement of the pineal gland. In this case report, two …
Published in International journal of Nursing Science Practice and Research · Vol. 10, Issue 2, 2024 · pp. 38–43 Read article
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Useful Medicinal Operative: Innovative Formulation of Zoloft
Abstract: A highly effective antidepressant is active metabolite hydrochloride. Zoloft is one of those drugs with one or even more asymmetrical centres where the biological effects of the isomers vary significantly from one another. Depression, dependence, and other anxiety-related illnesses are all treated with sertraline hydrochloride, which selectively blocks serotonine reuptake. The preferred configurations should typically be created as early as feasible in the biosynthesis of sertraline, which has two asymmetric …
Published in International Journal of Composite Materials and Matrices · Vol. 8, Issue 1, 2022 · pp. 19–22 Read article
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Ayurveda as an alternative Medicine for SARS-CoV
Abstract: The goal of this study was to look at the clinical evidence for complementary and alternative medicine treatments for major depressive disorder. The phrase depressive disorder was combined with St John’s wort, S-adenosylmethionine (SAM-e), exercise, acupuncture, omega-3 fatty acids, and folate in a PubMed search from January 1966 to February 2010. Only relevant human trials were selected. COVID-19, the current global health emergency, is not the first-time coronaviruses have posed …
Published in International Journal of Analytical and Applied Chemistry · Vol. 7, Issue 2, 2021 · pp. 28–36 Read article