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257 articles for “Drug”
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Major Analytical Problems in Current Pharmaceutical Drug Products
Abstract: Substances of pharmaceutical drug products go through thorough analyses to check the safety, efficacy as well as the quality of the final product. There are a number of shortcomings even though much has been done in the analytical methods used in recalls. Such challenges are those concerning method validation, sensitivity, specificity, reproducibility, and regulation. This article on major analytical problems in current pharmaceutical drug products outlines major limitations in the …
Published in International Journal of Analytical and Applied Chemistry · Vol. 11, Issue 1, 2025 · pp. 29–39 Read article
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Solubility Enhancement of Theophylline Drug Using Mixed Solvency Approach
Abstract: “Solubility enhancement” is one of the difficult tasks that have become a great challenge in formulation development of orally administered drugs having poor aqueous solubility. Poor aqueous solubility of drugs creates significant problems in producing formulations of sufficiently high bioavailability, thereby preventing the effective usage of these drugs. With the introduction of the concept of “mixed-solvency,” it is feasible to increase the solubility of poorly water-soluble drugs in aqueous solutions …
Published in International Journal of Chemical Separation Technology · Vol. 1, Issue 2, 2015 · pp. 1–4 Read article
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A Review on Applications of Bionanotechnology in Nanomedicine: A Theoretical Analysis of Drug Delivery System
Abstract: Nanotechnology is one of the most recent innovative disciplines in engineering with substantial benefits especially in nanomedicine. It holds a great potential with its application to create materials and devices within the range of the “nano” metric system. The creation of these vast materials can be applicable in diverse fields of science such as biology bionanotechnology, nanoelectronics, and nanomedicine. This field seeks to combine both engineering and medicine to solve …
Published in International journal of Nanobiotechnology · Vol. 6, Issue 1, 2020 · pp. 20–27 Read article
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Recent Advances in Aquasomes Carrier Nanotechnology for Drug Delivery
Abstract: Aquasomes are a nanobiopharmaceutical carrier device with nanocrystalline calcium phosphate or ceramic diamond particle center and a polyhydroxyl oligomeric film covering them. Aquasomes are spherical 60–300 nm objects that are used to deliver drugs and antigens. It was an effective carrier mechanism for bioactive molecules such as peptides, proteins, hormones, antigens, and genes to particular locations because of properties such as defense and preservation of fragile biological molecules, conformational integrity, …
Published in International journal of Nanobiotechnology · Vol. 7, Issue 1, 2021 · pp. 35–44 Read article
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Exploring the Current Practices of Nurses, Preparing and Administering Chemotherapeutic Drugs to Children
Abstract: Introduction: Emergence of chemotherapeutic drugs has immensely benefitted current prognosis of childhood cancers but unintentional exposure to harmful agents may endanger life of health care workers who repeatedly get exposed to cytotoxic drugs. Nurses’ safety can be ensured with evidence based standard protocols related to chemotherapeutic drug preparation and administration, use of PPE, proper handling of hazardous waste, spill management etc. Objective: To explore ongoing practices, casual daily routine activities, …
Published in International Journal of Nursing Critical Care · Vol. 6, Issue 2, 2020 · pp. 52–59 Read article
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Innovative Approaches to Molecular Synthesis for Drug Development
Abstract: The rapidly evolving field of drug development continually seeks innovative methodologies to enhance the efficiency, specificity, and scalability of molecular synthesis. This paper explores recent advancements in synthetic chemistry, focusing on techniques that have shown significant promise in addressing the challenges faced in drug discovery and development. Automated Synthesis: The advent of machine learning and artificial intelligence (AI) in synthetic chemistry has led to the development of automated synthesis platforms. …
Published in International Journal of Chemical Engineering and Processing · Vol. 10, Issue 2, 2024 · pp. 9–14 Read article
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Microneedle platform: An innovative way for transdermal drug delivery system.
Abstract: The transdermal route is employed as an alternate method in many therapeutic applications to get over the important drawbacks of oral medication delivery. Transdermal microneedle arrays have been used for drug administration via the skin for a very long time. Microneedles are devices with a reputation for being highly efficacious and flexible. Microneedles are devices with a reputation for being highly effective and flexible. Intellectual and industrial groups are interested …
Published in International journal of Nanobiotechnology · Vol. 10, Issue 1, 2024 Read article
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In silico evaluation for the repurposing of antiviral drugs towards multiple targets of monkey pox viral disease
Abstract: Objective: Monkeypox is a growing public health problem. The disease is caused by the monkeypox virus. The latest epidemic has been linked to previously unknown mutations and variations. Tecovirimat is a poxvirus medication that has been licenced by the US Food and Drug Administration (FDA). Otherwise, there is little pharmacopoeia and scientific interest inmonkeypox. Computational screening and molecular interactions were used in this work to investigate the possible repurposing of …
Published in International Journal of Animal Biotechnology and Applications · Vol. 9, Issue 1, 2023 · pp. 22–32 Read article
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In-Vitro Evaluation of Control Release of Drug with Carbon Based Nanomaterials
Abstract: Nanomaterials have been introduced as a novel & interesting materials due to their advance properties & their use in nanotechnology applications like nano-sensors, nano-chips, control & targeted drug delivery, diagnosis, gene therapy. These all possibilities are due to their physico-chemical & multifunctional biological characteristics. In medicine, control release of drug is a factor to reduce dosage form in revert reduce side effects. In this work, nanomaterials are using as a …
Published in International journal of Nanobiotechnology · Vol. 1, Issue 1-2, 2015 · pp. 14–18 Read article
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Preparation of Diclofenac Sodium Loaded Invasomes - A Novel Carrier for Drug Delivery
Abstract: Background: Diclofenac sodium is capable of providing benefit to patients suffering from: rheumatoid arthritis, osteoarthritis, and gout. Diclofenac sodium is a medicine that reduces inflammation and pain. It is also used to treat aches and pains, as well as problems with joints, muscles, and bones. The aim of the present work is to prepare diclofenac sodium invasomes by thin film hydration technique. Methodology: In the present study, for the preparation …
Published in International journal of Nanobiotechnology · Vol. 7, Issue 1, 2021 · pp. 45–50 Read article
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A DESCRIPTIVE STUDY TO ASSESS THE DRUG COMPLIANCE AMONG PATIENTS ATTENDING PSYCHIATRIC OUTPATIENT DEPARTMENTS IN SELECTED HOSPITAL OF DISTRICT FARIDKOT
Abstract: Non compliance to medication regimen is a serious problem. It is estimated that non compliance rates among mentally ill seems ranging from 20 to 80% with an average rate of 50%. There are numerous psychosocial factors which are affecting drug compliance. So a descriptive study was conducted to assess drug compliance among patients attending psychiatric outpatient department of selected hospitals of district Faridkot Punjab.The objectives of study were to assess …
Published in International Journal of Neurological Nursing · Vol. 8, Issue 1, 2022 · pp. 1–6 Read article
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Drug Delivery Systems
Abstract: Drug delivery is the strategy or procedure of overseeing a pharmaceutical compound to accomplish a restorative impact in human or animals. For the treatment of human illnesses, nasal and pneumonic routes of drug delivery are increasing expanding significance. These routes give promising contrasting options to parenteral drug delivery especially for peptide and protein therapeutics. For this reason, a few drug delivery frameworks have been figured and are being explored for …
Published in International Journal of Industrial Biotechnology and Biomaterials · Vol. 2, Issue 2, 2016 · pp. 6–10 Read article
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Statistical and Artificial Neural Network for the Determination of Thermo-Physical Properties of Fomoditine Drug Using Mixed Hydrotropy
Abstract: The experimental determination of thermo-physical properties of fomoditine drug–mixed hydrotrope concentration mixture is very time consuming as well as tedious process. Any tool helpful in estimation of these properties without experimentation can be of immense utility. In present work, other tools of determination of properties of fomoditine drug–mixed hydrotrope concentration blends were tried. A traditional statistical technique of linear regression (principle of least squares) was used to estimate the specific …
Published in International Journal of Chemical Engineering and Processing · Vol. 1, Issue 2, 2015 · pp. 1–6 Read article
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Synthesis and characterization of Calcium Alginate Nanoparticle for Drug Delivery Application
Abstract: The polymeric nanoparticles (PNPs) are prepared from biocompatible and biodegradable polymers such as chitosan, gelatin, sodium alginate and albumin in size between 10-1000 nm where the drug is dissolved, entrapped, encapsulated or attached to a nanoparticle matrix. Their nanometer-size promotes effective permeation through cell membranes and stability in the blood stream. These smart PNPs are widely used as carriers in the pharmaceutical sector for controlled release in drug delivery. In …
Published in International journal of Nanobiotechnology · Vol. 4, Issue 2, 2018 · pp. 35–41 Read article
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A study to assess the effectiveness of self instructional module (SIM) on knowledge regarding adverse effects of selected antipsychotic drugs among interns in selected nursing school’s of Belgaum
Abstract: A study to assess the effectiveness of self instructional module (SIM) on knowledge regarding adverse effects of selected antipsychotic drugs among interns in selected nursing school’s of Belgaum, was carried out for partial fulfillment of the requirement for the award of Master of the Degree of Nursing at KLE University Institute of Nursing Science Belgaum. The objectives of the study were, to assess the level of the knowledge regarding adverse …
Published in International journal of Nursing Science Practice and Research · Vol. 2, Issue 2, 2016 · pp. 29–32 Read article
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Effect of PTP on Knowledge of Staff Nurses for Safe Drug Administration in Pediatric Tuberculosis
Abstract: It is known that safe drug administration plays a very important role in the management of pediatric tuberculosis. The staff nurses being the core member of health team needs to be made aware of all the aspects of pediatric tuberculosis management especially drugs. The current study was conducted to assess the effect of a planned teaching programme (PTP) on knowledge of staff nurses regarding safe drug administration in pediatric tuberculosis. …
Published in International Journal of Pediatric Nursing · Vol. 3, Issue 2, 2017 · pp. 11–16 Read article
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Recent Advances in Fused Heterocyclic Pyridine Compounds for Bioactive Anti-Inflammatory Drug Discovery
Abstract: Heterocyclic compounds, particularly those fused with pyridine rings, have emerged as promising candidates in the search for novel bioactive agents with anti-inflammatory properties. This review highlights recent advances in the discovery and development of fused heterocyclic pyridine compounds as potential anti-inflammatory drugs. The unique structural properties of fused heterocycles contribute to their ability to modulate key inflammatory pathways. By targeting specific molecular targets involved in inflammation, such as cytokines, enzymes, …
Published in International Journal of Chemical Separation Technology · Vol. 10, Issue 1, 2024 · pp. 1–7 Read article
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Insights into the Recent Advancements in the Vibrant Area of Cubosomes Nanoparticles based Drug Delivery
Abstract: Cubosomes are square or rounded nanoparticles with internal cubic lattices that can be used. Cubosomes are a one-of-a-kind invention that spans the fields of food science, differential geometry, biological membranes, and digestion. Self-assembled cubosomes are effective drug delivery devices that have grown in popularity as a result of their discovery and nomination. Cubosomes have a honeycomb-like structure of bicontinuous water and lipid domains and are thermodynamically stable. Within the surfactant, …
Published in International journal of Nanobiotechnology · Vol. 7, Issue 1, 2021 · pp. 24–34 Read article
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Isolation and Characterization of Tamarind Seed Polysaccharides Being Used as a Biopolymer in Modern Drug Delivery System
Abstract: Tamarind seed polysaccharide (TSP) obtained from the seed of Tamarindus indica tree. It possesses different properties like high viscosity, broad pH tolerance, biocompatibility, mucoadhesive nature. It is used as thickener, stabilizer, gelling agent in food and pharmaceutical industries and Gums are widely used natural materials for conventional and novel dosage forms. The objective of present investigation was to search for a cheap and effective natural polymer that can be used …
Published in International Journal of Polymer Science and Engineering · Vol. 2, Issue 1, 2016 · pp. 1–6 Read article
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A STUDY TO EVALUATE THE EFFECTIVENESS OF INSTRUCTIONAL PROGRAMME ON KNOWLEDGE REGARDING MULTI DRUG RESISTANCE TUBERCULOSIS AMONG STAFF NURSES AT TERTIARY LEVEL TEACHING HOSPITAL DHARWAD”
Abstract: Research design: A quantitative research approach with pre-experimental one group pre-test, post-test design was adopted in this study.Objective: to evaluate the effectiveness of instructional programme on knowledge regarding multi drug resistance tuberculosis among staff nurses at tertiary level teaching hospital, Dharwad. Sample and sampling technique: A total of 30 staff nurses were selected by non – probability purposive sampling technique.Data Collection: The tool used for data collection was structured knowledge …
Published in International Journal of Nursing Critical Care · Vol. 8, Issue 1, 2022 · pp. 1–4 Read article